This article presents BCAM-Net, a bidirectional cross-attention multimodal framework for robust IoT spectrum sensing under generalized Gaussian impulsive noise....
This review examines aerodynamic drag reduction strategies for road vehicles, integrating insights from both experimental investigations and numerical simulations...
This study experimentally investigates a novel jacketed shell-and-tube heat exchanger integrating phase change cold storage and condensation heat transfer. Using...
Tech Science Press is pleased to announce that two additional journals have been selected for inclusion in CAB Abstracts, a leading database produced by CAB International (CABI). This milestone...
Gratitude, Growth, and Global Engagement The Canadian Journal of Urology (CJU) is pleased to share its 2025 annual highlights. Over the past year, the journal has maintained steady growth,...
This study aims to mitigate crosswind-induced performance degradation in Natural Draft Dry Cooling Towers used in power plants by developing and assessing...
Fluid flow through fractured rock masses is a key process controlling the safety and performance of deep geoengineering systems, shaped by the complex...
Aerodynamic research on road cars was reviewed in this work under the thread of reducing drag, with the awareness that this may succeed in effectively...
In response to the actual demands of the energy storage type organic Rankine power generation cycle, this study proposes a new type of jacketed shell...
Heat exchangers play a crucial role in thermal energy systems, with their performance directly impacting efficiency, cost, and environmental impact. A...
Objective: Current research highlights periodontal disease as a systemic inflammatory condition that may influence extra-oral diseases such as prostatic...
Discussions about the future of energy sources and environmental sustainability are becoming critical on a global scale. The energy sector plays a central...
The increasing integration of electric vehicle (EV) loads into power systems necessitates understanding their impact on stability. Small-magnitude perturbations,...
Objectives: Loneliness among left-behind adolescents is the most frequently reported emotional problem because of parental neglect. The present study...
The development of sustainable materials has encouraged the use of biopolymers as alternatives to synthetic polymers. Polymeric films have stood out for...
As attack techniques evolve and data volumes increase, the integration of artificial intelligence-based security solutions into industrial control systems...
This paper examines a model that combines vortex generators and leading-edge tubercles for controlling the laminar separation bubble (LSB) over an airfoil...
Skin cancer remains the most commonly diagnosed malignancy worldwide, with basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC), and melanoma...
Classical Hodgkin lymphoma (cHL) is characterized by rare Hodgkin/Reed-Sternberg (HRS) tumor cells that uniformly express cluster of differentiation (CD)30...
Quantitative analysis of aluminum-silicon (Al-Si) alloy microstructure is crucial for evaluating and controlling alloy performance. Conventional analysis...
Internet of Things (IoTs) devices are bringing about a revolutionary change our society by enabling connectivity regardless of time and location. However,...
Cancer remains one of the leading causes of morbidity and mortality worldwide, and its onset and progression are closely linked to dysregulated epigenetic...
We propose a special issue titled "Innovative Smart Polymeric Materials for Sustainable Energy Solutions: Bridging Advances in Energy and Biomedical...
Further advancements in the exploitation of unconventional resources, such as tight gas, shale gas, shale oil, coalbed methane, and natural gas hydrate,...
In today’s digital era, patterns are omnipresent, shaping many aspects of our lives. These patterns can be physically observed or computationally identified...
This special issue, “Applied Artificial Intelligence: Advanced Solutions for Engineering Real-World Challenges,” showcases the transformative power of...
This theme captures the essence of advanced technologies (AI, machine learning, big data), modern applications (climate change, smart cities, health research),...
The tumor microenvironment encompasses not only the tumor cells themselves, but also the surrounding fibroblasts, immunological and inflammatory cells,...
This special issue seeks original research and review articles on the roles of γδ T cells and invariant natural killer T (iNKT) cells in malignancies....
This study aims to mitigate crosswind-induced performance degradation in Natural Draft Dry Cooling Towers used in power plants by developing and assessing...
Fluid flow through fractured rock masses is a key process controlling the safety and performance of deep geoengineering systems, shaped by the complex...
Aerodynamic research on road cars was reviewed in this work under the thread of reducing drag, with the awareness that this may succeed in effectively...
In response to the actual demands of the energy storage type organic Rankine power generation cycle, this study proposes a new type of jacketed shell...
Heat exchangers play a crucial role in thermal energy systems, with their performance directly impacting efficiency, cost, and environmental impact. A...
Objective: Current research highlights periodontal disease as a systemic inflammatory condition that may influence extra-oral diseases such as prostatic...
Discussions about the future of energy sources and environmental sustainability are becoming critical on a global scale. The energy sector plays a central...
The increasing integration of electric vehicle (EV) loads into power systems necessitates understanding their impact on stability. Small-magnitude perturbations,...
Objectives: Loneliness among left-behind adolescents is the most frequently reported emotional problem because of parental neglect. The present study...
The development of sustainable materials has encouraged the use of biopolymers as alternatives to synthetic polymers. Polymeric films have stood out for...
As attack techniques evolve and data volumes increase, the integration of artificial intelligence-based security solutions into industrial control systems...
This paper examines a model that combines vortex generators and leading-edge tubercles for controlling the laminar separation bubble (LSB) over an airfoil...
Skin cancer remains the most commonly diagnosed malignancy worldwide, with basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC), and melanoma...
Classical Hodgkin lymphoma (cHL) is characterized by rare Hodgkin/Reed-Sternberg (HRS) tumor cells that uniformly express cluster of differentiation (CD)30...
Quantitative analysis of aluminum-silicon (Al-Si) alloy microstructure is crucial for evaluating and controlling alloy performance. Conventional analysis...
Internet of Things (IoTs) devices are bringing about a revolutionary change our society by enabling connectivity regardless of time and location. However,...
Cancer remains one of the leading causes of morbidity and mortality worldwide, and its onset and progression are closely linked to dysregulated epigenetic...
We propose a special issue titled "Innovative Smart Polymeric Materials for Sustainable Energy Solutions: Bridging Advances in Energy and Biomedical...
Further advancements in the exploitation of unconventional resources, such as tight gas, shale gas, shale oil, coalbed methane, and natural gas hydrate,...
In today’s digital era, patterns are omnipresent, shaping many aspects of our lives. These patterns can be physically observed or computationally identified...
This special issue, “Applied Artificial Intelligence: Advanced Solutions for Engineering Real-World Challenges,” showcases the transformative power of...
This theme captures the essence of advanced technologies (AI, machine learning, big data), modern applications (climate change, smart cities, health research),...
The tumor microenvironment encompasses not only the tumor cells themselves, but also the surrounding fibroblasts, immunological and inflammatory cells,...
This special issue seeks original research and review articles on the roles of γδ T cells and invariant natural killer T (iNKT) cells in malignancies....
In the rapidly evolving digital landscape, the interplay between social media and cultural identity among Afghan youth is of growing significance. This study examines how social media influences the digital culture of Afghan youth, using Social Identity Theory (SIT) to explore digital behaviors, identity formation, and cultural preservation. With a sample of 400 participants, the research addresses key gaps by analyzing the impact of social media on societal norms, cultural values, and online relationships. The…
Zero-shot learning as an emerging approach in image captioning techniques, has garnered significant attention from researchers in recent years due to its ability to accomplish tasks without requiring specific category training data. Existing zero-shot image captioning schemes largely rely on traditional language models, which exhibit low efficiency and suboptimal generation quality. To address this issue, this study proposes Hamiltonian Monte Carlo for Image Captioning (HMCIC). This method first models the image captioning task as a…
Objective: Intestinal barrier disruption is a critical event in sepsis and ischemia–reperfusion (I/R) injury. Enteric glial cells (EGCs) maintain barrier integrity by secreting glial cell line–derived neurotrophic factor (GDNF). This study aimed to determine whether Dexmedetomidine (Dex) protects the intestinal barrier via α7-nicotinic acetylcholine receptor (α7-nAChR) signaling in EGCs. Methods: An in vitro EGC-intestinal epithelial cell (IEC) co-culture system and a murine intestinal I/R model were established. EGCs were selectively ablated in vivo using benzalkonium chloride (BAC).…
Objectives: Glioblastoma multiforme (GBM) is a highly aggressive brain tumor characterized by extensive transcriptional and epigenetic dysregulation. Brother of the Regulator of Imprinted Sites (BORIS/CTCFL) has been implicated in oncogenic transcriptional programs in several cancers, but its role in GBM remains poorly defined. This study aimed to characterize BORIS-associated transcriptional programs in GBM and to assess their functional relevance using integrative computational and experimental approaches. Methods: Transcriptomic data from The Cancer Genome Atlas (TCGA)-GBM and…
Objectives: Permanent middle cerebral artery occlusion (pMCAO) can lead to hippocampal damage through multiple linked pathways such as reactive oxidative stress (ROS), neuroinflammation mediated by NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3), tumour necrosis factor-alpha (TNF-α), and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), and glutamate excitotoxicity involving N-methyl-D-aspartate receptor subunits 2a and 2b (NR2a/NR2b) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR/GluR1). The hippocampus, which is essential for memory and cognition, is at a substantial…
Objective: Cisplatin is a widely used chemotherapeutic agent due to its ability to damage DNA in the treatment of cancer. However, its clinical application is often limited by adverse effects on normal tissues, especially the kidneys. Understanding the molecular mechanisms of cisplatin-induced nephrotoxicity is crucial for developing strategies to mitigate its side effects. In this study, we aimed to elucidate the molecular mechanisms underlying cisplatin-induced DNA damage and apoptosis in human renal epithelial cells, with…
Atherosclerosis (AS) remains a major contributor to cardiovascular disease (CVD) mortality worldwide. Its development involves dysregulated lipid handling, persistent vascular inflammation, and endothelial cell (EC) dysfunction, influenced by genetic, environmental, and lifestyle factors. Increasing evidence highlights a pivotal role of endoplasmic reticulum (ER) stress as a molecular link between lipid dysregulation and inflammatory signaling in AS pathogenesis. ER stress is triggered by modified LDL, oxidized lipids, hyperhomocysteinemia, oxidative stress (OS), and disrupted calcium (Ca2+) homeostasis, leading…
Obesity-related asthma is a distinct clinical phenotype, characterized by severe respiratory symptoms, reduced responsiveness to conventional glucocorticoid therapy, and a significantly increase in disease burden. With the rising global prevalence of obesity, the number of individuals affected by obesity-related asthma is steadily growing, presenting a pressing public health issue. The pathogenesis of obesity-related asthma is multifactorial, involving a complex interplay of metabolic and immune pathways. Key mechanisms include dysregulated T-cell differentiation, pro-inflammatory macrophage polarization, oxidative…
Objective: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). Soluble interleukin-2 receptor alpha (sIL-2Rα) has been implicated in MS pathogenesis, but its mechanisms remain unclear. This study investigates how sIL-2Rα exacerbates MS by modulating microglial activation and antibody-dependent cellular cytotoxicity (ADCC) in an experimental autoimmune encephalomyelitis (EAE) mouse model. Methods: Female C57BL/6J mice were induced with EAE and treated with sIL-2Rα. Clinical symptoms, histopathology, and molecular changes were…
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, most commonly driven by chronic hepatitis B virus (HBV) infection. The HBV X protein (HBx) plays a central role in hepatocarcinogenesis by regulating transcription, signal transduction, epigenetic modification, and interactions with noncoding RNAs. This review summarizes current advances in HBx-mediated signaling pathways and mutation-specific functions, highlighting its potential as a prognostic biomarker and therapeutic target, and providing insights for future strategies in HCC treatment…
Diffuse intrinsic pontine glioma (DIPG) is a pediatric brainstem tumor with a very poor prognosis, characterized by immunosuppressive tumor microenvironment (TME) that limits immune infiltration, including a significant reduction in circulating natural killer (NK) cells. This drop in NK cell levels and activity may promote tumor growth and immune evasion, making NK cells a promising target for immunotherapy. NK cells can attack and eliminate DIPG tumor cells, including glioma stem cells, while counteracting certain immune…
Metabolic dysfunction-associated fatty liver disease (MAFLD) and chronic kidney disease (CKD) have shown a marked global increase in prevalence, placing a substantial burden on public health and healthcare systems worldwide. Epidemiological data demonstrate a significant overlap between these two conditions, with further evidence from research identifying common pathophysiological features, such as lipid metabolism dysregulation, disrupted energy balance, and chronic systemic inflammation. Mitochondria are central to the pathophysiology of both diseases. In addition to their role…
Ischemia-reperfusion (I/R) injury induces region-specific neuronal vulnerability within the hippocampus, with the cornu ammonis 1 (CA1) subfield particularly prone to delayed neuronal death. While intrinsic neuronal factors have been implicated, emerging evidence highlights the decisive contribution of astrocyte endfeet (AEF)—specialized perivascular structures that regulate ion and water homeostasis, glutamate clearance, and blood–brain barrier (BBB) stability. This review synthesizes structural and molecular alterations of AEF across the CA1–CA3 subfields following I/R and their correlation with neuronal…
Objectives: Prostate cancer (PCa) is a highly prevalent male malignancy with limited efficacy in advanced stages. Dysregulated modulation of necroptosis was reported to be tightly correlated with PCa initiation and progression. Herein, we aimed to identify necroptosis-associated long non-coding RNAs (lncRNAs) and delineate their functional roles in PCa through an integrated approach combining bioinformatic analyses and in vitro experimental validation. Methods: RNA sequencing data and corresponding clinical information of PCa were downloaded from The Cancer Genome…
Disulfidptosis is a newly identified form of regulated cell death (RCD) first described in 2023, representing a significant advance in understanding programmed cell death pathways. This unique cell death modality is characterized by abnormal intracellular accumulation of disulfide bonds and disruption of redox homeostasis, leading to cytoskeletal collapse without caspase activation. Disulfidptosis is primarily triggered by glucose deprivation in cells with high expression of solute carrier family 7 member 11 (SLC7A11). Under these conditions, insufficient…
Lung cancer remains the leading cause of cancer-related mortality worldwide, primarily driven by metabolic reprogramming and immune evasion mechanisms within tumor cells. To adapt to the nutrient-deprived tumor microenvironment (TME), lung cancer cells undergo profound metabolic reprogramming, characterized by enhanced glycolysis (the Warburg effect), increased glutamine dependency (mediated by GLS1), and accelerated lipid synthesis (involving enzymes such as FASN). These metabolic alterations not only remodel the TME but also dampen antitumor immune responses by promoting…
Guest Editors: Qi Chen; Yunhui Tang Deadline: 31 December 2026
Guest Editors: Dawei Jiang; Miaojun Xu; Bo Jiang; Zijian Wu Deadline: 31 December 2026
Guest Editors: Changhong LINGHU; Hoon Eui Jeong; Ying Jiang; Jiangtao Su; Yangchengyi... Deadline: 30 December 2026
Guest Editors: Fátima Martel Deadline: 30 November 2026
Guest Editors: Wei-Chiang Hong; Yi Liang; Ming-Wei Li; Zhong-Yi Yang Deadline: 30 November 2026
Guest Editors: Emilio Cervantes Deadline: 31 October 2026
Guest Editors: Maria Letizia Motti; Immacolata Belviso Deadline: 31 October 2026
Guest Editors: Batyrkhan Omarov; Daniyar Sultan; Bakhytzhan Kulambayev Deadline: 30 October 2026
Guest Editors: Daniel-Ioan Curiac; Dan Pescaru Deadline: 15 October 2026
Guest Editors: Barmak Honarvar Shakibaei Asli Deadline: 01 October 2026
Guest Editors: Antonella Petrillo; Fabio De Felice Deadline: 30 September 2026
Guest Editors: Sergio Cassese; Giuseppe Gallo Deadline: 30 September 2026
Guest Editors: Wenfeng Zheng; Lirong Yin; Shan Liu Deadline: 31 August 2026
Guest Editors: Mohammad Shokouhifar; Frank Werner Deadline: 31 August 2026
Guest Editors: Dulf Eva-H.; Kovacs Levente; Denes-Fazakas Lehel; Pintea Paul-Andrei Deadline: 31 August 2026
Guest Editors: Ali BOURGI Deadline: 31 July 2026






