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Congenital Heart Disease
ARTICLE

A Comprehensive Brain MRI and Neurodevelopmental Dataset in Children with Tetralogy of Fallot

Background: The life-course management of children with tetralogy of Fallot (TOF) has focused on demonstrating brain structural alterations, developmental...

Congenital Heart Disease
REVIEW

Precision Pharmacology in Pediatric Congenital Heart Disease: Gene Editing and Organoid Models Addressing Developmental Challenges

Pediatric congenital heart disease (CHD) pharmacotherapy faces three fundamental barriers: developmental pharmacokinetic complexity, anatomic-genetic...

International Journal of Mental Health...
REVIEW

A Double-Edged Sword: A Scoping Review of the Mental Health Aspects of Parentification

Objectives: Parentification, a role reversal where children assume age-inappropriate duties in the family, is a significant childhood adversity often...

Oncology Research
REVIEW

A Review on Novel Applications of Nanoparticles in Pediatric Oncology

Nanomedicine has evolved significantly over the last decades and expanded its applications in pediatric oncology, which represents a special domain with...

Oncology Research
REVIEW

Molecular Pathology of Ovarian Endometrioid Carcinoma: A Review

Ovarian endometrioid carcinoma (OEC) accounts for ~10% of epithelial ovarian cancers and displays broad morphologic diversity that complicates diagnosis...

Computer Modeling in Engineering & Sciences
REVIEW

A Comprehensive Survey on AI-Assisted Multiple Access Enablers for 6G and beyond Wireless Networks

The envisioned 6G wireless networks demand advanced Multiple Access (MA) schemes capable of supporting ultra-low latency, massive connectivity, high spectral...

Computer Modeling in Engineering & Sciences
REVIEW

Deep Learning and Federated Learning in Human Activity Recognition with Sensor Data: A Comprehensive Review

Human Activity Recognition (HAR) represents a rapidly advancing research domain, propelled by continuous developments in sensor technologies and the Internet...

Computer Modeling in Engineering & Sciences
ARTICLE

Offshore Wind Turbines Anomalies Detection Based on a New Normalized Power Index

Anomaly detection in wind turbines involves emphasizing its ability to improve operational efficiency, reduce maintenance costs, extend their lifespan,...

Computer Modeling in Engineering & Sciences
ARTICLE

Deployable and Accurate Time Series Prediction Model for Earth-Retaining Wall Deformation Monitoring

Excavation-induced deformations of earth-retaining walls (ERWs) can critically affect the safety of surrounding structures, highlighting the need for...

Computers, Materials & Continua
ARTICLE

Adversarial Perturbation for Sensor Data Anonymization: Balancing Privacy and Utility

Recent advances in wearable devices have enabled large-scale collection of sensor data across healthcare, sports, and other domains but this has also...

Computers, Materials & Continua
ARTICLE

Dual-Perspective Evaluation of Knowledge Graphs for Graph-to-Text Generation

Data curation is vital for selecting effective demonstration examples in graph-to-text generation. However, evaluating the quality of Knowledge Graphs...

Computers, Materials & Continua
COMMENTARY

From Data to Discovery: How AI-Driven Materials Databases Are Reshaping Research

AI-driven materials databases are transforming research by integrating experimental and computational data to enhance discovery and optimization. Platforms...

Computer Modeling in Engineering & Sciences
REVIEW

Gait Planning, and Motion Control Methods for Quadruped Robots: Achieving High Environmental Adaptability: A Review

Legged robots have always been a focal point of research for scholars domestically and internationally. Compared to other types of robots, quadruped robots...

Computer Modeling in Engineering & Sciences
REVIEW

Optimization-Based Approaches to Uncertainty Analysis of Structures Using Non-Probabilistic Modeling: A Review

Response analysis of structures involving non-probabilistic uncertain parameters can be closely related to optimization. This paper provides a review...

Computer Modeling in Engineering & Sciences
REVIEW

Smoothed Particle Hydrodynamics (SPH) Simulations of Drop Evaporation: A Comprehensive Overview of Methods and Applications

The evaporation of micrometer and millimeter liquid drops, involving a liquid-to-vapor phase transition accompanied by mass and energy transfer through...

Computer Modeling in Engineering & Sciences
REVIEW

On Optimizing Resource Allocation: A Comparative Review of Resource Allocation Strategies in HetNets

Resource allocation remains a challenging issue in communication networks, and its complexity is continuously increasing with the densification of the...

Oncology Research
Special Issue

Transcriptome Analysis in Tumor Microenvironment and Tumor Heterogeneity

The tumor microenvironment encompasses not only the tumor cells themselves, but also the surrounding fibroblasts, immunological and inflammatory cells,...

Computer Modeling in Engineering & Sciences
Special Issue

Cutting-Edge Security and Privacy Solutions for Next-Generation Intelligent Mobile Internet Technologies and Applications

The mobile internet has revolutionized our daily lives, providing continuous connectivity, communication, and access to a wide range of services and applications...

Computers, Materials & Continua
Special Issue

Machine Vision Detection and Intelligent Recognition

Machine vision detection and intelligent recognition are important research areas in computer vision with wide-ranging applications in manufacturing,...

Computers, Materials & Continua
Special Issue

Deep Learning based Object Detection and Tracking in Videos

Object detection and tracking in videos has become an increasingly important area of research due to its potential applications in a variety of domains...

Computer Modeling in Engineering & Sciences
Special Issue

Computer-Aided Uncertainty Modeling and Reliability Evaluation for Complex Engineering Structures

With the progress of science and technology, more and more complex engineering structures are serving in extreme environments. In the service life of...

BIOCELL
Special Issue

Extracellular Vesicles and Cancer

Extracellular vesicles (EVs) are phospholipid bilayer vesicles released from tumor and non-tumor cells for intercellular communication. EVs contain...

Computer Modeling in Engineering & Sciences
Special Issue

Peridynamics and its Current Progress

The peridynamics proposed by Silling [1] is a non-local theory of solid mechanics. It redefines the problems by using integral equations rather than partial...

Computer Modeling in Engineering & Sciences
Special Issue

Recent Developments on Computational Biology-I

In modern time, experts started to use interdisciplinary properties with the developing of technology and science. Thus, these disciplines provide more...

Congenital Heart Disease
ARTICLE

A Comprehensive Brain MRI and Neurodevelopmental Dataset in Children with Tetralogy of Fallot

Background: The life-course management of children with tetralogy of Fallot (TOF) has focused on demonstrating brain structural alterations, developmental...

Congenital Heart Disease
REVIEW

Precision Pharmacology in Pediatric Congenital Heart Disease: Gene Editing and Organoid Models Addressing Developmental Challenges

Pediatric congenital heart disease (CHD) pharmacotherapy faces three fundamental barriers: developmental pharmacokinetic complexity, anatomic-genetic...

International Journal of Mental Health...
REVIEW

A Double-Edged Sword: A Scoping Review of the Mental Health Aspects of Parentification

Objectives: Parentification, a role reversal where children assume age-inappropriate duties in the family, is a significant childhood adversity often...

Oncology Research
REVIEW

A Review on Novel Applications of Nanoparticles in Pediatric Oncology

Nanomedicine has evolved significantly over the last decades and expanded its applications in pediatric oncology, which represents a special domain with...

Oncology Research
REVIEW

Molecular Pathology of Ovarian Endometrioid Carcinoma: A Review

Ovarian endometrioid carcinoma (OEC) accounts for ~10% of epithelial ovarian cancers and displays broad morphologic diversity that complicates diagnosis...

Computer Modeling in Engineering & Sciences
REVIEW

A Comprehensive Survey on AI-Assisted Multiple Access Enablers for 6G and beyond Wireless Networks

The envisioned 6G wireless networks demand advanced Multiple Access (MA) schemes capable of supporting ultra-low latency, massive connectivity, high spectral...

Computer Modeling in Engineering & Sciences
REVIEW

Deep Learning and Federated Learning in Human Activity Recognition with Sensor Data: A Comprehensive Review

Human Activity Recognition (HAR) represents a rapidly advancing research domain, propelled by continuous developments in sensor technologies and the Internet...

Computer Modeling in Engineering & Sciences
ARTICLE

Offshore Wind Turbines Anomalies Detection Based on a New Normalized Power Index

Anomaly detection in wind turbines involves emphasizing its ability to improve operational efficiency, reduce maintenance costs, extend their lifespan,...

Computer Modeling in Engineering & Sciences
ARTICLE

Deployable and Accurate Time Series Prediction Model for Earth-Retaining Wall Deformation Monitoring

Excavation-induced deformations of earth-retaining walls (ERWs) can critically affect the safety of surrounding structures, highlighting the need for...

Computers, Materials & Continua
ARTICLE

Adversarial Perturbation for Sensor Data Anonymization: Balancing Privacy and Utility

Recent advances in wearable devices have enabled large-scale collection of sensor data across healthcare, sports, and other domains but this has also...

Computers, Materials & Continua
ARTICLE

Dual-Perspective Evaluation of Knowledge Graphs for Graph-to-Text Generation

Data curation is vital for selecting effective demonstration examples in graph-to-text generation. However, evaluating the quality of Knowledge Graphs...

Computers, Materials & Continua
COMMENTARY

From Data to Discovery: How AI-Driven Materials Databases Are Reshaping Research

AI-driven materials databases are transforming research by integrating experimental and computational data to enhance discovery and optimization. Platforms...

Computer Modeling in Engineering & Sciences
REVIEW

Gait Planning, and Motion Control Methods for Quadruped Robots: Achieving High Environmental Adaptability: A Review

Legged robots have always been a focal point of research for scholars domestically and internationally. Compared to other types of robots, quadruped robots...

Computer Modeling in Engineering & Sciences
REVIEW

Optimization-Based Approaches to Uncertainty Analysis of Structures Using Non-Probabilistic Modeling: A Review

Response analysis of structures involving non-probabilistic uncertain parameters can be closely related to optimization. This paper provides a review...

Computer Modeling in Engineering & Sciences
REVIEW

Smoothed Particle Hydrodynamics (SPH) Simulations of Drop Evaporation: A Comprehensive Overview of Methods and Applications

The evaporation of micrometer and millimeter liquid drops, involving a liquid-to-vapor phase transition accompanied by mass and energy transfer through...

Computer Modeling in Engineering & Sciences
REVIEW

On Optimizing Resource Allocation: A Comparative Review of Resource Allocation Strategies in HetNets

Resource allocation remains a challenging issue in communication networks, and its complexity is continuously increasing with the densification of the...

Oncology Research
Special Issue

Transcriptome Analysis in Tumor Microenvironment and Tumor Heterogeneity

The tumor microenvironment encompasses not only the tumor cells themselves, but also the surrounding fibroblasts, immunological and inflammatory cells,...

Computer Modeling in Engineering & Sciences
Special Issue

Cutting-Edge Security and Privacy Solutions for Next-Generation Intelligent Mobile Internet Technologies and Applications

The mobile internet has revolutionized our daily lives, providing continuous connectivity, communication, and access to a wide range of services and applications...

Computers, Materials & Continua
Special Issue

Machine Vision Detection and Intelligent Recognition

Machine vision detection and intelligent recognition are important research areas in computer vision with wide-ranging applications in manufacturing,...

Computers, Materials & Continua
Special Issue

Deep Learning based Object Detection and Tracking in Videos

Object detection and tracking in videos has become an increasingly important area of research due to its potential applications in a variety of domains...

Computer Modeling in Engineering & Sciences
Special Issue

Computer-Aided Uncertainty Modeling and Reliability Evaluation for Complex Engineering Structures

With the progress of science and technology, more and more complex engineering structures are serving in extreme environments. In the service life of...

BIOCELL
Special Issue

Extracellular Vesicles and Cancer

Extracellular vesicles (EVs) are phospholipid bilayer vesicles released from tumor and non-tumor cells for intercellular communication. EVs contain...

Computer Modeling in Engineering & Sciences
Special Issue

Peridynamics and its Current Progress

The peridynamics proposed by Silling [1] is a non-local theory of solid mechanics. It redefines the problems by using integral equations rather than partial...

Computer Modeling in Engineering & Sciences
Special Issue

Recent Developments on Computational Biology-I

In modern time, experts started to use interdisciplinary properties with the developing of technology and science. Thus, these disciplines provide more...

State-Space Reduction Techniques Exploiting Specific Constraints for Quantum Search Initialization, Application to an Outage Planning Problem

Quantum search has emerged as one of the most promising fields in quantum computing. State-of-the-art quantum search algorithms enable the search for specific elements in a distribution by monotonically increasing the density of these elements relative to the rest of the distribution. These kinds of algorithms demonstrate a theoretical quadratic speed-up on the number of queries compared to classical search algorithms in unstructured spaces. Unfortunately, the major part of the existing literature applies quantum search…

Computer Systems Science and Engineering
Article

Attribute-Based Encryption for Secure Access Control in Personal Health Records

Attribute-based Encryption (ABE) enhances the confidentiality of Electronic Health Records (EHR) (also known as Personal Health Records (PHR)) by binding access rights not to individual identities, but to user attribute sets such as roles, specialties, or certifications. This data-centric cryptographic paradigm enables highly fine-grained, policy-driven access control, minimizing the need for identity management and supporting scalable multi-user scenarios. This paper presents a comprehensive and critical survey of ABE schemes developed specifically for EHR/PHR systems over…

Phyton-International Journal of Experimental Botany
Article

Survey of Barley Sodium Transporter HvHKT1;1 Variants and Their Functional Analysis

Barley (Hordeum vulgare L.) employs the Na⁺ transporter HvHKT1;1, which is an N⁺-selective transporter. This study characterized the full-length HvHKT1;1 (HvHKT1;1-FL) and three mRNA variants (HvHKT1;1-V1, -V2, and -V3), which encode polypeptides of 64.7, 54.0, 40.5, and 32.9 kDa, respectively. Tissue-specific expression profiling revealed that HvHKT1;1-FL is the most abundant transcript across leaf, sheath, and root tissues under normal conditions, with the highest expression in leaves. Under 150 mM NaCl stress, HvHKT1;1-FL and its variants showed a dynamic, time-dependent expression pattern,…

Phyton-International Journal of Experimental Botany
Review

Cadmium Hyperaccumulation in Plants: Mechanistic Insights and Ecological Implications

Cadmium (Cd), a highly toxic heavy metal, represents a major global environmental threat due to its widespread dispersion through anthropogenic activities. Environmental Cd contamination poses significant risks to living organisms, including humans, animals, and plants. Certain plant species have evolved Cd hyperaccumulating capabilities to adapt to high-Cd habitats, playing critical roles in phytoremediation strategies. Here we review the biodiversity and biogeography of Cd hyperaccumulators, the underlying mechanisms of Cd uptake and accumulation, and the ecological…

Phyton-International Journal of Experimental Botany
Article

Melatonin Enhances Antioxidant Defense and Physiological Stability in Grapevine (Vitis vinifera L.) Cultivars ‘Merlot’ and ‘Erciş’ under UV-B Stress

Climate change-driven environmental stresses, particularly ultraviolet-B (UV-B) radiation, pose severe threats to grapevine (Vitis vinifera L.) productivity and physiological stability. This study investigated the protective role of melatonin in in vitro plantlets of two grapevine cultivars, ‘Merlot’ and ‘Erciş’, subjected to low (≈8.25 μW cm⁻², 16 h) and high (≈33 μW cm⁻², 4 h) UV-B exposure. Significant cultivar-specific responses were observed (p < 0.001). The ‘Erciş’ cultivar exhibited higher oxidative stress, with malondialdehyde (MDA) levels reaching 24.30 mmol g⁻¹…

Phyton-International Journal of Experimental Botany
Article

Survival Status and Trend Prediction of the Endangered Plant Cupressus gigantea Populations in Tibet Plateau

Cupressus gigantea is an endemic endangered tree species in the Tibet Plateau, and studying the survival status of the different C. gigantea populations and revealing the main environmental factors that affect the population survival are particularly significant for the conservation and sustainable development of endangered species. Based on the 28 sample plots, the Hierarchical Cluster Method was used to classify the C. gigantea populations into four community types. Age structure diagrams were drawn based on the structure of…

Phyton-International Journal of Experimental Botany
Article

Early Chemodiversity of Alkaloids in Seedlings Annona Species

The seedling phase represents an initial and critical stage for the establishment of individuals in the ecosystem. During this stage, specialized metabolites contribute to survival; however, studies analyzing the presence of these molecules and the reasons for their production and accumulation are still scarce. Annonaceae is a botanical family recognized for the chemodiversity of its secondary metabolites; nearly 1000 alkaloids have been reported in approximately 150 adult specimens. The aim of this study was to…

Phyton-International Journal of Experimental Botany
Review

A Review of Phenolic Compounds: From Biosynthesis and Ecological Roles to Human Health and Nutrition

Phenolic compounds represent a broad and structurally diverse class of plant secondary metabolites with importance for both plant biology and human health. This review provides a comprehensive overview of their biosynthesis, chemical diversity, multifaceted functions in plants, roles in the wider ecosystem, and significance in human nutrition and biotechnology. Primarily synthesized via the phenylpropanoid pathway, these compounds encompass major classes such as lignin, flavonoids, and tannins. Within the plant, they perform critical functions including providing…

Phyton-International Journal of Experimental Botany
Review

Key Plant Transcription Factors in Crop Tolerance to Abiotic Stresses

Abiotic stresses, such as drought, heavy metals, salinity, and extreme temperatures, are among the most common adverse threats that restrict the use of land for agriculture and limit crop growth and productivity. As sessile organisms, plants defend themselves from abiotic stresses by developing various tolerance mechanisms. These mechanisms are governed by several biochemical traits. The biochemical mechanisms are the products of key genes that express under specific conditions. Interestingly, the expression of these genes is…

Phyton-International Journal of Experimental Botany
Review

Traditional Uses, Polysaccharide Pharmacology, and Active Components Biosynthesis Regulation of Dendrobium officinale: A Review

Dendrobium officinale (DO) is a well-recognized medicinal and edible plant with a long history of application in traditional medicinal practices across China and Southeast Asia. Recent studies have demonstrated that DO is abundant in diverse bioactive compounds, including polysaccharides (DOP), flavonoids, alkaloids, and bibenzyls thought to exert a range of pharmacological effects, such as anti-tumor and immunomodulatory effects. However, our comprehensive understanding of two key aspects—pharmacological functions and biosynthetic mechanisms—of DO’s major constituents remains limited, especially when considered…

Phyton-International Journal of Experimental Botany
Article

Genome-Wide Scanning Analysis for MYB and MADS in Hydrangea macrophylla and the Inflorescence Type Related Candidate Genes Expression Analysis

Hydrangea macrophylla is a popular ornamental shrub with a lot of economic and aesthetic value. It is known for its different flower shapes (lacecap and mophead) and the way its flowers change color depending on the pH of the soil. Even though it is important for gardening, we still don’t know much about the molecular processes that lead to flower growth. The purpose of this study was to find and study SNP-related genes and transcription factors…

Phyton-International Journal of Experimental Botany
Article

Germination and Early Growth Responses of Bread Wheat (Triticum aestivum L.) to Cadmium Stress

Cadmium (Cd) contamination is a major environmental stressor that adversely affects crop germination and early development. This study assessed the impact of increasing Cd concentrations (0.125 to 1 g/L) on seed germination and early seedling growth in three bread wheat (Triticum aestivum L.) cultivars: Achtar, Lina, and Snina. The results revealed a clear dose-dependent inhibitory effect of Cd. Germination percentage (GP) significantly declined with increasing Cd levels, while mean germination time was progressively delayed, particularly at…

Phyton-International Journal of Experimental Botany
Review

Beyond Photomorphogenesis: Multifaceted Roles of BBX Transcription Factors in Plant Stress Responses and Breeding Perspectives

Extensive transcriptomic reprogramming is triggered by biotic and abiotic stresses in plants, with coordinated regulation mediated through multiple transcription factor families, such as WRKY, MYB, NAC, and BBX proteins. Among these, B-box (BBX) proteins represent a distinct class of zinc finger transcription factors characterized by the presence of conserved B-box domains. They serve as central regulators in plant photomorphogenesis and developmental processes. Accumulating genetic and biochemical evidence demonstrates that BBX family members orchestrate plant responses…

Phyton-International Journal of Experimental Botany
Article

Genetic Diversity of Tuberose (Polianthes tuberosa L.) Germplasm through Molecular Approaches to Obtain Desirable Plant Materials for Future Breeding Programs

The present study investigated the genetic diversity of 24 germplasms of Polianthes tuberosa L. via 16 inter simple sequence repeat (ISSR) marker techniques. The research findings revealed that the ISSR markers presented higher levels of band reproducibility and were more efficient at clustering germplasms. Among the 16 markers examined in this study, 12 had a complete polymorphism rate of 100%. The molecular analysis revealed a PIC ranging from 0.079 to 0.373, with a mean value of…

Phyton-International Journal of Experimental Botany
Article

The Combination of Appropriate Drip Irrigation and Straw Mulching Increased the Yield of Maize

Optimizing drip irrigation with straw mulch return represents a promising sustainable intensification strategy for revolutionizing regional water management. This 2-year controlled field experiment examined straw incorporation effects (removal and return) and drip irrigation levels (200, 350, 500 mm) on maize carbon-nitrogen metabolism, root bleeding sap characteristics, dry matter accumulation, and yield. Dry matter and yield increased with irrigation amount. Under 200–350 mm irrigation, straw return enhanced root bleeding intensity; elevated nitrogen, phosphorus, potassium, calcium, and…

Phyton-International Journal of Experimental Botany
Article

Valorisation of Northern Moroccan Centaurium erythraea: Targeted Phytochemistry, Antioxidant, Antimicrobial Efficacy and Drug Likeness Benchmarking

Centaurium erythraea Rafn (“Gosset El Haya”) has long been prized in North African folk medicine, yet Moroccan chemobiological data remain scarce. Ethanol extracts of northern Moroccan aerial parts were profiled by high-performance liquid chromatography (HPLC) and found rich in phenolics, dominated by 4-hydroxybenzoic acid (57.8%) and naringin (10.3%). The extract exhibited strong antioxidant power in the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay, with a half-maximal inhibitory concentration (IC₅₀) of ≈74 µg mL⁻¹, and a total antioxidant capacity (TAC) of…