Tech Science Press - Publisher of Open Access Journals

Featured

All

Articles

Special Issues

Computer Modeling in Engineering & Sciences
REVIEW

A Comprehensive Review of Complex Logical Reasoning in Large Vision-Language Models

Large Vision-Language Models (LVLMs) have achieved strong performance in multimodal perception, understanding, and generation, but their ability to perform...

Computer Modeling in Engineering & Sciences
ARTICLE

Computer Modelling of Thin, Soft Biological Tissues: A Decoupled Strategy for Standardizing Isotropic and Anisotropic Corneal Biomechanics

The development of accurate digital twin models of the human cornea is a key factor for planning and monitoring eye treatments and clinical supervision....

Computer Modeling in Engineering & Sciences
ARTICLE

A Lagrangian Generalized Finite Difference Method for the Bubble Flow with Large Density Difference Considering the Continuous Surface Force Model

Due to the complex and dynamic nature of multi-phase interfaces, accurately capturing interface evolution remains one of the key challenges in multi-phase...

BIOCELL
REVIEW

Targeting Skeletal Muscle Melatonin-MT₂ Signaling to Attenuate the Obesity-Cancer Axis: A Metabolic Perspective

Obesity and metabolic syndrome promote malignancies through chronic inflammation and sustained activation of insulin and insulin-like growth factor-1...

BIOCELL
REVIEW

Cholesterol-Mediated Remodelling of the Tumour-Immune Landscape: The Role of Non-Coding RNAs

Non-coding RNAs (ncRNAs) and cholesterol metabolism have independently been recognized as critical regulators of cancer progression. NcRNAs modulate various...

BIOCELL
REVIEW

Improving Cancer Therapy: The Strong Synergy of Ginsenosides and Chemotherapy

Despite the advancements achieved in chemotherapy, cancer continues to remain a formidable and lethal global threat, ranking as the second leading cause...

Computers, Materials & Continua
ARTICLE

An Edge-Assisted Internet-of-Vehicles Computing Framework for Fair Tail-Risk Allocation in Cooperative Autonomous Driving

Connected automated driving increasingly relies on cooperative perception from onboard sensors, roadside units (RSUs), smart traffic lights, and vehicle-to-everything...

Computers, Materials & Continua
REVIEW

Topological Materials and Machine Learning: A Comprehensive Review

The unique topological properties of the electronic band structures in topological materials have increasingly attracted attention in both fundamental...

Computers, Materials & Continua
ARTICLE

DFT-Based Computational Investigation of Mechanical, Acoustic and Thermal Properties of Cd_1-xZn_xTe Alloys for Radiation Detector Applications

Zinc substitution in Cd1−xZnxTe (CZT) alloys emerges as a powerful strategy for engineering their structural, elastic, mechanical, acoustic and thermal...

Computers, Materials & Continua
ARTICLE

Lightweight AI-Powered Intrusion Detection via Edge Computing

A lightweight flow-based intrusion detection system is proposed for identifying Mirai-based distributed denial-of-service attacks in Internet of Things...

Computers, Materials & Continua
ARTICLE

MSA-ConvNeXt: Predicting Magnetism of Doped Two-Dimensional Nanomaterials via Multi-Scale Convolution and Attention Mechanisms

In doped two-dimensional nanomaterials, magnetism is one of the important physical properties. By introducing foreign doping atoms or molecules, the electronic...

Computers, Materials & Continua
REVIEW

Machine Learning for Robotics: Algorithms, Applications, and Emerging Trends

The integration of Deep Learning, Deep Reinforcement Learning, and massive Vision-Language-Action (VLA) foundation models has catalysed a profound paradigm...

Oncology Research
REVIEW

Cancer Drug Development in Never-Smoker Lung Cancer: Targeted and Immune-Based Therapeutic Strategies

Lung cancer in individuals who have never smoked (LCINS) represents a clinically and biologically distinct subset of non–small cell lung cancer, driven...

Oncology Research
REVIEW

Navigating the Metabolic-Genomic Paradigm: Mitochondrial Reprogramming as a Driver of Cancer Plasticity

Breast cancer (BC) management has transitioned from histological classification to molecular subtyping, yet therapeutic resistance and intratumor heterogeneity...

Oncology Research
REVIEW

Epigenetic Modulators and Immunotherapy in Malignant Melanoma

Despite the use of targeted and/or immune-based therapeutic approaches, mortality rates among melanoma patients are high, mainly due to drug-induced resistance...

European Cytokine Network
REVIEW

Emerging viral infections: role of flavivirus NS1-mediated rewiring of PRR signaling

Flaviviruses, including Dengue, West Nile, Zika, and Japanese encephalitis viruses, are arthropod-borne RNA viruses that pose an increasing global health...

Oncology Research
Special Issue

Advances in the Discovery and Development of Novel Anticancer Compounds

The rapid evolution of chemical biology, medicinal chemistry, and molecular pharmacology continues to drive the discovery of innovative anticancer compounds...

Oncology Research
Special Issue

Epigenetics and Epitranscriptomics in Cancer Biology and Therapy

Cancer development and therapeutic response are governed not only by genetic alterations but also by dynamic regulatory mechanisms at the epigenetic and...

Energy Engineering
Special Issue

Model-based and Learning Methods for Optimization and Management of Energy Flows in Decentralized Smart Grids

The transition toward decentralized smart grids is reshaping the way energy is generated, exchanged, controlled, and consumed. The increasing penetration...

BIOCELL
Special Issue

Epigenetic and ncRNA Biomarkers in Cancer: Diagnostic and Prognostic Value

Cancer remains one of the leading causes of morbidity and mortality worldwide, and its onset and progression are closely linked to dysregulated epigenetic...

Oncology Research
Special Issue

Targeting the Tumor Microenvironment: Emerging Insights into Cancer Progression and Therapeutics

The tumor microenvironment (TME) plays a crucial role in cancer progression, metastasis, and resistance to therapy, prompting a shift in focus from targeting...

Oncology Research
Special Issue

Tumor Biomarkers for Diagnosis, Prognosis and Targeted Therapy

Tumor biomarkers have become an essential foundation for advancements in cancer diagnosis, prognosis, and targeted therapy. As oncology moves towards...

Journal of Polymer Materials
Special Issue

Innovative Smart Polymeric Materials for Sustainable Energy Solutions: Bridging Advances in Energy and Biomedical Applications

We propose a special issue titled "Innovative Smart Polymeric Materials for Sustainable Energy Solutions: Bridging Advances in Energy and Biomedical...

Computer Modeling in Engineering & Sciences
Special Issue

Machine learning and Blockchain for AIoT: Robustness, Privacy, Trust and Security

Artificial Intelligence of Things (AIoT) is considered a collaborative application of artificial intelligence (AI) and the Internet of Things (IoT). The...

Computer Modeling in Engineering & Sciences
REVIEW

A Comprehensive Review of Complex Logical Reasoning in Large Vision-Language Models

Large Vision-Language Models (LVLMs) have achieved strong performance in multimodal perception, understanding, and generation, but their ability to perform...

Computer Modeling in Engineering & Sciences
ARTICLE

Computer Modelling of Thin, Soft Biological Tissues: A Decoupled Strategy for Standardizing Isotropic and Anisotropic Corneal Biomechanics

The development of accurate digital twin models of the human cornea is a key factor for planning and monitoring eye treatments and clinical supervision....

Computer Modeling in Engineering & Sciences
ARTICLE

A Lagrangian Generalized Finite Difference Method for the Bubble Flow with Large Density Difference Considering the Continuous Surface Force Model

Due to the complex and dynamic nature of multi-phase interfaces, accurately capturing interface evolution remains one of the key challenges in multi-phase...

BIOCELL
REVIEW

Targeting Skeletal Muscle Melatonin-MT₂ Signaling to Attenuate the Obesity-Cancer Axis: A Metabolic Perspective

Obesity and metabolic syndrome promote malignancies through chronic inflammation and sustained activation of insulin and insulin-like growth factor-1...

BIOCELL
REVIEW

Cholesterol-Mediated Remodelling of the Tumour-Immune Landscape: The Role of Non-Coding RNAs

Non-coding RNAs (ncRNAs) and cholesterol metabolism have independently been recognized as critical regulators of cancer progression. NcRNAs modulate various...

BIOCELL
REVIEW

Improving Cancer Therapy: The Strong Synergy of Ginsenosides and Chemotherapy

Despite the advancements achieved in chemotherapy, cancer continues to remain a formidable and lethal global threat, ranking as the second leading cause...

Computers, Materials & Continua
ARTICLE

An Edge-Assisted Internet-of-Vehicles Computing Framework for Fair Tail-Risk Allocation in Cooperative Autonomous Driving

Connected automated driving increasingly relies on cooperative perception from onboard sensors, roadside units (RSUs), smart traffic lights, and vehicle-to-everything...

Computers, Materials & Continua
REVIEW

Topological Materials and Machine Learning: A Comprehensive Review

The unique topological properties of the electronic band structures in topological materials have increasingly attracted attention in both fundamental...

Computers, Materials & Continua
ARTICLE

DFT-Based Computational Investigation of Mechanical, Acoustic and Thermal Properties of Cd_1-xZn_xTe Alloys for Radiation Detector Applications

Zinc substitution in Cd1−xZnxTe (CZT) alloys emerges as a powerful strategy for engineering their structural, elastic, mechanical, acoustic and thermal...

Computers, Materials & Continua
ARTICLE

Lightweight AI-Powered Intrusion Detection via Edge Computing

A lightweight flow-based intrusion detection system is proposed for identifying Mirai-based distributed denial-of-service attacks in Internet of Things...

Computers, Materials & Continua
ARTICLE

MSA-ConvNeXt: Predicting Magnetism of Doped Two-Dimensional Nanomaterials via Multi-Scale Convolution and Attention Mechanisms

In doped two-dimensional nanomaterials, magnetism is one of the important physical properties. By introducing foreign doping atoms or molecules, the electronic...

Computers, Materials & Continua
REVIEW

Machine Learning for Robotics: Algorithms, Applications, and Emerging Trends

The integration of Deep Learning, Deep Reinforcement Learning, and massive Vision-Language-Action (VLA) foundation models has catalysed a profound paradigm...

Oncology Research
REVIEW

Cancer Drug Development in Never-Smoker Lung Cancer: Targeted and Immune-Based Therapeutic Strategies

Lung cancer in individuals who have never smoked (LCINS) represents a clinically and biologically distinct subset of non–small cell lung cancer, driven...

Oncology Research
REVIEW

Navigating the Metabolic-Genomic Paradigm: Mitochondrial Reprogramming as a Driver of Cancer Plasticity

Breast cancer (BC) management has transitioned from histological classification to molecular subtyping, yet therapeutic resistance and intratumor heterogeneity...

Oncology Research
REVIEW

Epigenetic Modulators and Immunotherapy in Malignant Melanoma

Despite the use of targeted and/or immune-based therapeutic approaches, mortality rates among melanoma patients are high, mainly due to drug-induced resistance...

European Cytokine Network
REVIEW

Emerging viral infections: role of flavivirus NS1-mediated rewiring of PRR signaling

Flaviviruses, including Dengue, West Nile, Zika, and Japanese encephalitis viruses, are arthropod-borne RNA viruses that pose an increasing global health...

Oncology Research
Special Issue

Advances in the Discovery and Development of Novel Anticancer Compounds

The rapid evolution of chemical biology, medicinal chemistry, and molecular pharmacology continues to drive the discovery of innovative anticancer compounds...

Oncology Research
Special Issue

Epigenetics and Epitranscriptomics in Cancer Biology and Therapy

Cancer development and therapeutic response are governed not only by genetic alterations but also by dynamic regulatory mechanisms at the epigenetic and...

Energy Engineering
Special Issue

Model-based and Learning Methods for Optimization and Management of Energy Flows in Decentralized Smart Grids

The transition toward decentralized smart grids is reshaping the way energy is generated, exchanged, controlled, and consumed. The increasing penetration...

BIOCELL
Special Issue

Epigenetic and ncRNA Biomarkers in Cancer: Diagnostic and Prognostic Value

Cancer remains one of the leading causes of morbidity and mortality worldwide, and its onset and progression are closely linked to dysregulated epigenetic...

Oncology Research
Special Issue

Targeting the Tumor Microenvironment: Emerging Insights into Cancer Progression and Therapeutics

The tumor microenvironment (TME) plays a crucial role in cancer progression, metastasis, and resistance to therapy, prompting a shift in focus from targeting...

Oncology Research
Special Issue

Tumor Biomarkers for Diagnosis, Prognosis and Targeted Therapy

Tumor biomarkers have become an essential foundation for advancements in cancer diagnosis, prognosis, and targeted therapy. As oncology moves towards...

Journal of Polymer Materials
Special Issue

Innovative Smart Polymeric Materials for Sustainable Energy Solutions: Bridging Advances in Energy and Biomedical Applications

We propose a special issue titled "Innovative Smart Polymeric Materials for Sustainable Energy Solutions: Bridging Advances in Energy and Biomedical...

Computer Modeling in Engineering & Sciences
Special Issue

Machine learning and Blockchain for AIoT: Robustness, Privacy, Trust and Security

Artificial Intelligence of Things (AIoT) is considered a collaborative application of artificial intelligence (AI) and the Internet of Things (IoT). The...

Recent Breakthroughs in Leveraging MoS₂ to Transcend the Performance Bottlenecks of Perovskite Solar Cells

The power conversion efficiency of perovskite solar cells has increased rapidly; however, interfacial-defect-induced non-radiative recombination, ion migration, and sensitivity to moisture, oxygen, and thermal stress continue to cause open-circuit voltage losses and a limited operational lifetime. Owing to its tunable energy levels, high carrier mobility, and compact hydrophobic layered structure, two-dimensional MoS₂ can serve as an electron or hole transport layer, an interfacial buffer layer, or an additive, enabling favorable energy-level alignment and optimized interfacial charge-transfer…

Chalcogenide Letters
article

High Hardness Ge₄₅As₄₀Se₁₅ Glasses Based on Ball-Milling and Chalcogenide Glasses Molded by Spark Plasma Sintering

In this work, Ge₄₅As₄₀Se₁₅ chalcogenide glass was prepared using spark plasma sintering. This method synthesizes glass powder into blocks through a certain temperature and pressure, which is an effective densification and high-precision molding of infrared transparent blocks and lenses. Through X-ray diffraction (XRD) and differential scanning calorimetry analysis, we tracked the gradual evolution of the powder during ball milling and observed the existence of a glass transition temperature in the glass after powder hot pressing. This

Chalcogenide Letters
article

Synthesis, Crystal Structure, Optical, and Thermal Properties of a Novel Quaternary Selenide EuErAgSe₃

A novel quaternary selenide, EuErAgSe₃, has been synthesized for the first time. The phase forms upon annealing in the 1120–1800 K range and retains its crystal structure upon cooling to ambient conditions. The phase was prepared by the ampoule method from EuSe and AgErSe₂ powders, followed by annealing at 1270 ± 10 K for up to 300 h. Powder X-ray diffraction revealed that EuErAgSe₃ crystallizes in the AgBiS₂ structure type (space group Fm-3m) with the lattice parameter a…

Chalcogenide Letters
article

Electronic Properties of MoSe₂/ZrSe₃ Junction Field Effect Transistor

Transition metal dichalcogenides (TMDs) and transition metal trichalcogenides (TMTCs) exhibit tunable electronic properties, and when stacked together in their two dimensional (2D) forms, they can display distinctive electronic properties beyond those of conventional heterostructures. In this study, we fabricated for the first time junction field effect transistor (JFET) by stacking MoSe₂, a transition metal dichalcogenide (TMD), with ZrSe₃, a transition metal trichalcogenide (TMTC). We characterized its electrical properties, where the device’s electrical characteristics were analyzed based…

Chalcogenide Letters
article

The Effect of Washing on the Structural, Morphological, and Compositional Properties of CuS Nanopowder Synthesis via Chemical Bath Technique

Nanopowder copper sulphide CuS has been synthesised successfully via the chemical bath deposition method. Two samples of precipitated CuS nanopowder were prepared at molar concentration of 0.5 M from [CuSO₄·5H₂O and Na₂S₂O₃·5H₂O] and 0.05 M from [Na₂EDTA·2H₂O]. Both samples were annealed at 150°C for one hour in air. The effects of washing and nonwashing on the structural, morphological, and compositional properties were studied. The X-ray diffraction (XRD) patterns showed that both samples have a CuS hexagonal structure…

Chalcogenide Letters
article

Bandgap Tunable PbSnSeS Quaternary Quantum Dots for near-Infrared Optoelectronic and Solar Cell Applications

Semiconductor quantum dots (QDs) with tunable narrow bandgaps have emerged as promising materials for next-generation near-infrared (NIR) optoelectronic and photovoltaic devices because their optical properties can be tailored through composition and quantum confinement. Among IV–VI chalcogenide nanomaterials, quaternary alloy systems provide greater compositional flexibility than conventional binary and ternary counterparts; however, PbSnSeS quantum dots remain largely unexplored despite their potential for broadband infrared applications. Here, the structural, electronic, and optical properties of PbSnSeS quaternary QDs…

Chalcogenide Letters
article

Influence of Germanium Substitution on the DC Electrical Properties and Energy Density of States in Pb_50−xGe_xTe₅₀ Ternary Chalcogenide Alloys

This study investigates the structural evolution and DC electrical properties of Pb_50−xGe_xTe₅₀ ternary chalcogenide alloys with varying germanium concentrations (x = 5, 10, 15, 20). Synthesized via the melt-quenching technique, the alloys were characterized using Scanning Electron Microscopy (SEM) and temperature-dependent electrical resistivity measurements within the range of 290–475 K. Microstructural analysis revealed that increasing Ge substitution significantly promotes matrix densification, reducing porosity and improving inter-granular connectivity. The DC conductivity exhibits a systematic increase with Ge…

Energy Engineering
Article

Verification of Mitigation Capability for Total Loss of Feedwater Accident and Sensitivity Study on Feed-and-Bleed Cooling in a CPR1000 Nuclear Power Plant

Total loss of feedwater accident is a typical transient among the design extension conditions for pressurized water reactor nuclear power plants, directly related to the loss of core cooling capability. Chinese nuclear safety regulations require in-depth analysis of such conditions, while most of the Generation II and modified Generation II units currently in operation were designed prior to the issuance of these regulatory requirements, and their mitigation capability remains to be verified. To evaluate the…

Energy Engineering
Article

Analyze the Impact of Weather on Rooftop Solar Power Generation by Applying Ensemble Learning: Lessons from Kurunegala, Sri Lanka

Rooftop solar photovoltaic (PV) systems operate under weather conditions that differ significantly from Standard Test Conditions (STC), particularly in tropical regions. This study examines the impact of climatic factors on rooftop PV power generation in the Kurunegala district of Sri Lanka using measured power output and meteorological data. Three grid-connected PV systems with a capacity of 5 kW were monitored over six months, with hourly power output and inverter temperature recorded during the daytime. Corresponding…

Energy Engineering
Article

Performance Simulation Research on Vapor Compression Condensation Heat Compensation Constant Temperature and Humidity Air Conditioning System under Low Humidity Conditions

To reduce the reheating energy consumption in traditional constant temperature and humidity air conditioning systems, a constant temperature and humidity air conditioning system with condensation heat compensation function is proposed. This system performs reheating treatment on the supply air by combining condensation heat recovery with electric heating, realizing decoupled control of temperature and humidity and ensuring control accuracy. A system model and corresponding experimental platform are established to verify the model’s accuracy, and the experimental…

Energy Engineering
Article

Characterization of Bubble Dynamics in Nanofluid Flow under External Magnetic Field: Experimental and Numerical Approach

The magnetohydrodynamics of bubbly nanofluid flow in a horizontal pipe was studied. The drag-reduction effect of the behavior of a magnetohydrodynamic nanofluid in bubbly flow was experimentally verified by generating bubbles in the flow. The study examined the effects of the magnetic field on bubble formation by observing bubble characteristics, including shape, size, and trajectory. The experimental analysis adopted an optical system using a high-speed video camera. A MATLAB code was developed to track bubble…

Energy Engineering
Article

Smart Load Forecasting and Load Scheduling in Agriculture Irrigation Using Deep Learning Techniques

Agricultural irrigation consumes a large share of electricity in rural areas, creating predictable peak conditions on distribution systems that can lead to grid instability and unreliability. Classic load-forecasting and scheduling methods are time-consuming and unable to respond rapidly to fluctuating irrigation demand. Additionally, most traditional methods require a stable internet connection to function and therefore cannot readily adapt to seasonal changes or crop-specific irrigation requirements. This creates inefficiencies in energy consumption and inconsistencies in water…

Energy Engineering
Article

A Data-Driven Method for Rapid Prediction of Polarization Curves in Proton Exchange Membrane Electrolysis Cell

The prediction of the steady-state performance of the electrolysis cell is not only crucial for evaluating the rationality of its design and operational benchmarks, but also provides an important foundation for understanding its dynamic response behavior. This paper presents an efficient data-driven method based on three-dimensional two-phase numerical simulation and machine learning (ML) to rapidly predict the steady-state performance of proton exchange membrane electrolysis cells (PEMEC) under multi-physics field coupling conditions. The framework is based…

Energy Engineering
Article

Investigation of Sputtered TiO₂ Thin Films and Modeling of TiO₂-Based Heterojunctions with p-Si and p-GaAs

In this study, thin films of titanium dioxide (TiO₂) were deposited onto glass and indium tin oxide (ITO) substrates at room temperature, using plasma-assisted pulsed DC sputtering with a 99.9% pure stoichiometric TiO₂ target. Our research aims to investigate the influence of film thickness on the optical, structural, and morphological properties of TiO₂ nanostructured thin films, as well as its impact on the photovoltaic performance of heterojunctions where TiO₂ serves as the emitter. Using advanced PRISA software,…

Energy Engineering
Article

Uncertainty-Aware Distributed Optimization for IoEV Smart Charging and Battery Health Management in Cyber-Physical Smart Grids

The rapid expansion of electric vehicles (EVs) and the emergence of the Internet of Electric Vehicles (IoEV) have created considerable operational challenges for modern power systems. Large-scale EV charging can cause peak demand surges, voltage instability, and inefficient utilization of renewable energy resources when charging activities are not effectively coordinated. This study proposes an uncertainty-aware distributed optimization framework for smart EV charging in cyber-physical smart grids, in which charging schedules are coordinated while simultaneously considering…

Energy Engineering
Article

Optimization of Pyrolysis Temperature for Activated Carbon Production from Durian Shell and Eggshell for Energy Storage Applications

Agricultural waste has received increased attention as a sustainable precursor for activated carbon manufacture because of its availability, inexpensive price, and ecological benefits. However, the search for the right biomass and optimization of the activation process remain one of the major challenges in the production of high-performance composites in energy storage applications. In this study, pyrolysis of durian and eggshells was performed for activated carbon production using sodium sulfite (Na₂SO₃) and orthophosphoric acid (H₃PO₄) as activating…