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  • Open Access

    ARTICLE

    ChatGPT, Loneliness, and Well-Being among International PhD Students in Malaysia: A Mixed-Methods Study

    Tianyu Zhao1, Xiaoli Zhao2, Kenny S. L. Cheah3,*, Ye Zhang3

    International Journal of Mental Health Promotion, Vol.27, No.12, pp. 2023-2038, 2025, DOI:10.32604/ijmhp.2025.071322 - 31 December 2025

    Abstract Background: Despite access to university counseling services, many students underutilize them due to cultural stigma, language barriers, and perceived irrelevance. As a result, ChatGPT has emerged as an informal, always-available support system. This study investigates how international PhD students in Malaysia navigate loneliness, mental well-being, and social disconnection through interactions with Generative AI (mainly ChatGPT. Methods: Using a mixed-methods design, the study surveyed 155 international doctoral students and analyzed quantitative responses across four dimensions: loneliness, well-being (WHO-5), perceived social support, and AI-facilitated emotional support. Additionally, open-ended responses were examined using Latent Dirichlet Allocation (LDA) to identify… More >

  • Open Access

    ARTICLE

    Understanding Young Adults’ Social Media Anxiety: Mediating Role of Upward Social Comparison and the Moderating Role of Psychological Resilience

    Jinqian Li1, Jianhong Wu2,*

    International Journal of Mental Health Promotion, Vol.27, No.12, pp. 1883-1896, 2025, DOI:10.32604/ijmhp.2025.071306 - 31 December 2025

    Abstract Background: Platform algorithms driving content presentation are profoundly shaping the experience of younger users. While prior research has examined anxiety stemming from young adults’ social media usage, the link between upward social comparison and anxiety remains unclear. This study aims to investigate the mediating role of upward social comparison in this relationship and determine the moderating role of psychological resilience. Methods: A cross-sectional survey was conducted among 562 young Chinese adults aged 18–35 (53% female). Data were collected via an online questionnaire employing validated measurement instruments, including scales for social media usage patterns, upward comparator behaviour… More >

  • Open Access

    ARTICLE

    Family Organization and Resilience in Chinese Primary Students: Mediating Effects of Proactive Coping and Mindfulness

    Jingyuan Yu, Xueyan Wei*, Jinghui Wang

    International Journal of Mental Health Promotion, Vol.27, No.12, pp. 1929-1948, 2025, DOI:10.32604/ijmhp.2025.071233 - 31 December 2025

    Abstract Background: Chinese elementary students face mental health challenges due to excessive academic pressures. Previous research has indicated that resilience is crucial for improving their mental health, which is fostered by a supportive family environment. This study, therefore, explored the impact of family organization on children’s resilience and examined whether proactive coping and mindfulness mediate this relationship. Methods: Data were collected from 702 elementary school students (grades 3–6) in 3 cities in China using a multi-stage sampling procedure. Validated scales measured family organization, proactive coping, mindfulness, and resilience. The hypothesized model was tested using Structural Equation Modeling… More >

  • Open Access

    ARTICLE

    Determining the Emotions and Views of Patients with Post-Cesarean Surgical Site Infection: A Qualitative Study

    Elçin Alaçam1,*, Mualla Yılmaz2

    International Journal of Mental Health Promotion, Vol.27, No.12, pp. 1989-2005, 2025, DOI:10.32604/ijmhp.2025.071033 - 31 December 2025

    Abstract Background: Post-cesarean surgical site infection is a frequent complication with significant consequences for maternal, physical, and psychological well-being. This study explored women’s lived experiences of post-cesarean surgical site infection, focusing on emotional responses, treatment experiences, and perceived psychosocial impact. Methods: A qualitative study was conducted using thematic analysis of semi-structured interviews with 23 patients hospitalized due to post-cesarean surgical site infection, selected through purposeful sampling between 15 August 2022, and 15 January 2024. Results: The mean age of the participants in the study was 28.69 ± 5.07 years. Of them, 13 were high school graduates, and 22… More >

  • Open Access

    ARTICLE

    Alienation and Life Satisfaction: Mediation Effects of Social Identity and Hope among University Students

    Shu-Hsuan Chang1, Der-Fa Chen1, Jing-Tang Sie1, Kai-Jie Chen2, Zhe-Wei Liao1, Tai-Lung Chen1, Yao-Chung Cheng3,4,*

    International Journal of Mental Health Promotion, Vol.27, No.12, pp. 1907-1927, 2025, DOI:10.32604/ijmhp.2025.068264 - 31 December 2025

    Abstract Background: Interpersonal alienation has increasingly been recognized as a salient risk factor affecting university students’ psychological adjustment and life satisfaction. Guided by Social Identity and Self-Categorization theories, this study examines how alienation influences life satisfaction through the mediating roles of social identity and hope. Methods: This study surveyed 492 Taiwanese undergraduate students (53.7 percent female, mean age 21.08 years) from 60 universities using convenience sampling in May 2023. Data were collected through an online questionnaire distributed via faculty-managed teaching media platforms. Measures included perceived social identity, state hope, interpersonal alienation, and life satisfaction. All instruments were… More >

  • Open Access

    ARTICLE

    Bioactive Potential of Calophyllum inophyllum: Phytochemical Profiles, Biological Activities, and In Silico Pharmacokinetic Predictions

    Luksamee Vittaya1,*, Chakhriya Chalad1, Sittichoke Janyong2, Nararak Leesakul3

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4091-4115, 2025, DOI:10.32604/phyton.2025.074891 - 29 December 2025

    Abstract Calophyllum inophyllum is a tropical plant that could have useful medicinal properties for pharmaceutical and cosmetic applications. The present study extracted the flower, fruit, leaf, twig, and bark of the plant by maceration in different organic solvents. The correlation between bioactive compounds and their biological activities was investigated, with emphasis on their therapeutic relevance through in silico pharmacokinetic predictions using SwissADME. Qualitative and quantitative analyses were conducted to determine the total phenolic, flavonoid, and saponin contents of the extracts. Spectral analysis of the extracts revealed –OH, C=O, C=C, and C–H functional groups. The antioxidant activity of the… More > Graphic Abstract

    Bioactive Potential of <i>Calophyllum inophyllum</i>: Phytochemical Profiles, Biological Activities, and <i>In Silico</i> Pharmacokinetic Predictions

  • Open Access

    ARTICLE

    Forecasting Modeling Tool of Crop Diseases across Multiple Scenarios: System Design, Implementation, and Applications

    Mintao Xu1,#, Zichao Jin1,#, Yangyang Tian1, Jingcheng Zhang1,*, Huiqin Ma1, Yujin Jing1, Jiangxing Wu2, Jing Zhai2

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4059-4078, 2025, DOI:10.32604/phyton.2025.074422 - 29 December 2025

    Abstract The frequent outbreaks of crop diseases pose a serious threat to global agricultural production and food security. Data-driven forecasting models have emerged as an effective approach to support early warning and management, yet the lack of user-friendly tools for model development remains a major bottleneck. This study presents the Multi-Scenario Crop Disease Forecasting Modeling System (MSDFS), an open-source platform that enables end-to-end model construction-from multi-source data ingestion and feature engineering to training, evaluation, and deployment-across four representative scenarios: static point-based, static grid-based, dynamic point-based, and dynamic grid-based. Unlike conventional frameworks, MSDFS emphasizes modeling flexibility, allowing… More >

  • Open Access

    ARTICLE

    Phytochemical Composition and Pharmacological Effects of Extracts from Gilia capitata Sims

    Oleh Koshovyi1, Amal D. Premarathna2, Rando Tuvikene2, Valdas Jakštas3,4, Vaidotas Žvikas3, Yurii Hrytsyk5, Lyubov Grytsyk5, Andriy Grytsyk5, Jaan Liira6, Ain Raal1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3991-4019, 2025, DOI:10.32604/phyton.2025.074153 - 29 December 2025

    Abstract Gilia capitata Sims (Polemoniaceae) is an annual herbaceous plant widely distributed in western North America and cultivated as an ornamental flower. The detailed chemical composition and pharmacological properties of this plant have not been previously reported. This study aimed to investigate the chemical composition and pharmacological activity of aqueous-ethanolic extracts derived from different plant parts (herb, flowers, stems, roots, and fruits). HPLC analysis identified 12 phenolic compounds and 16 amino acids in the aqueous-ethanolic extracts obtained from these plant parts. The biological effects of the extracts were evaluated in vitro, including cytotoxicity, anti-inflammatory response, and wound-healing potential.… More >

  • Open Access

    ARTICLE

    Melatonin Priming Enhances Potassium Dichromate Stress Tolerance and Morpho-Physiological Performance via Genetic Modulation in Melon (Cucumis melo L.) Plant

    Tai Liu1,#, Huichun Xu1,#, Sikandar Amanullah2,*, Ye Che1, Ling Zhang1, Zeyu Jiang1, Weiyi Bi1, Lei Zhu1, Di Wang1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4117-4137, 2025, DOI:10.32604/phyton.2025.074131 - 29 December 2025

    Abstract Heavy metal accumulation in agricultural soil is primarily driven by pesticides, polluted water, and industrial gas emissions, which pose threats to sustainable crop production. Chromium (Cr) stress has an adverse impact on plant development and metabolism, but approaches to reduce its toxicity and enhance plant resistance remain limited. Melatonin is a potent antioxidant involved in regulating various morpho-physiological functions of plants under different abiotic stresses. In this study, we investigated the impact of exogenous melatonin to mitigate the negative effects of potassium dichromate (PD) stress in melon plants and analyzed genetic modulation of morphological, physiological,… More >

  • Open Access

    ARTICLE

    Genome-Wide Identification and Functional Characterization of UGT Gene Family in Sorghum bicolor with Insights into SbUGT12’s Role in C4 Photosynthesis

    Wenxiang Zhang1,2, Wenning Cui1, Juan Huang3, Zhangen Lu1, Kuijing Liang1, Lingbao Wang1,2, Shanshan Wei1,2, Liran Shi1, Huifen Li1, Xiaoli Guo1,2,*, Jianhui Ma4,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3893-3912, 2025, DOI:10.32604/phyton.2025.073736 - 29 December 2025

    Abstract UDP-glycosyltransferases (UGTs) play essential roles in plant secondary metabolism and stress responses, yet their composition and functions in Sorghum bicolor, a model C4 plant, remain inadequately characterized. This study identified 196 SbUGT genes distributed across all 10 chromosomes and classified them into 16 subfamilies (A–P) through phylogenetic analysis. Among these, 61.2% were intronless, and 10 conserved motifs, including the UGT-specific PSPG box, were identified. Synteny analysis using MCScanX revealed 12 segmental duplication events and conserved syntenic relationships with other Poaceae species (rice, maize, and barley). Promoter analysis uncovered 125 distinct cis-acting elements, predominantly associated with stress and… More >

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