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  • Open Access

    ARTICLE

    SPP1 and the risk score model to improve the survival prediction of patients with hepatocellular carcinoma based on multiple algorithms and back propagation neural networks

    WENLI ZENG1, FENG LING2, KAINUO DANG3, QINGJIA CHI3,*

    BIOCELL, Vol.47, No.3, pp. 581-592, 2023, DOI:10.32604/biocell.2023.025957 - 03 January 2023

    Abstract Hepatocellular carcinoma (HCC) is associated with poor prognosis and fluctuations in immune status. Although studies have found that secreted phosphoprotein 1 (SPP1) is involved in HCC progression, its independent prognostic value and immune-mediated role remain unclear. Using The Cancer Genome Atlas and Gene Expression Omnibus data, we found that low expression of SPP1 is significantly associated with improved survival of HCC patients and that SPP1 expression is correlated with clinical characteristics. Univariate and multivariate Cox regression confirmed that SPP1 is an independent prognostic factor of HCC. Subsequently, we found that T cell CD4 memory-activated monocytes,… More >

  • Open Access

    VIEWPOINT

    DNA polymerase θ (POLQ): A druggable DNA polymerase for homologous recombination-deficient cancer cells

    MERAN KESHAWA EDIRIWEERA*

    BIOCELL, Vol.47, No.3, pp. 441-444, 2023, DOI:10.32604/biocell.2023.025747 - 03 January 2023

    Abstract Irregularities in the DNA repair pathways are frequently observed in cancer. Dysregulated DNA repair pathways support growth advantages to tumor cells. DNA polymerase-theta (POLQ) is an error-prone DNA polymerase involved in double-strand break repair through microhomology-mediated end joining (MMEJ). POLQ also mediates translesion DNA synthesis and it is largely not expressed in normal cells. POLQ is overexpressed in a range of cancer cells, including homologous recombination (HR) deficient cancer cells. In HR deficient cells, MMEJ is crucial as a backup DNA repair pathway, indicating the indispensable role of POLQ-mediated MMEJ in HR deficient cancer cells. More >

  • Open Access

    ARTICLE

    Structural characterization of four Rhododendron spp. chloroplast genomes and comparative analyses with other azaleas

    XIAOJUN ZHOU1,*, MENGXUE LIU1, LINLIN SONG2

    BIOCELL, Vol.47, No.3, pp. 657-668, 2023, DOI:10.32604/biocell.2023.026781 - 03 January 2023

    Abstract Azalea is a general designation of Rhododendron in the Ericaceae family. Rhododendron not only has high ornamental value but also has application value in ecological protection, medicine, and scientific research. In this study, we used Illumina and PacBio sequencing to assemble and annotate the entire chloroplast genomes (cp genomes) of four Rhododendron species. The chloroplast genomes of R. concinnum, R. henanense subsp. lingbaoense, R. micranthum, and R. simsii were assembled into 207,236, 208,015, 207,233, and 206,912 bp, respectively. All chloroplast genomes contain eight rRNA genes, with either 88 or 89 protein-coding genes. The four cp genomes were compared and analyzed by More >

  • Open Access

    ARTICLE

    Pilot Test for Nitrogen Foam Flooding in Low Permeability Reservoir

    Xinyu Zhou1,2, Jia Huang1,2, Yuchen Qian1,2, Wenli Luo1,2, Lisha Qi3, Jie Wang3, Zhibin Jiang3, Hao Kang4,*

    Energy Engineering, Vol.120, No.3, pp. 763-774, 2023, DOI:10.32604/ee.2023.025893 - 03 January 2023

    Abstract

    Due to the characteristics of reservoir formation, the producing level of low permeability reservoir is relatively very low. It is hard to obtain high recovery through conventional development schemes. Considering the tight matrix, complex fracture system, low production level of producers, and low recovery factor of M block in Xinjiang oilfield, it is selected for on-site pilot test of nitrogen foam flooding. Detailed flooding scheme is made and the test results are evaluated respectively both for producers and injectors. The pressure index, filling degree, and fluid injection profile are found to be all improved in injectors

    More >

  • Open Access

    ARTICLE

    An Evaluation to the Performance of Evacuated Tube Solar Heaters for Arid and Hot Areas

    Asaad H. Sayer1, Samah Hussein Kadhim1, Hameed B. Mahood2,*

    Energy Engineering, Vol.120, No.3, pp. 587-596, 2023, DOI:10.32604/ee.2023.025407 - 03 January 2023

    Abstract Solar energy applications could be the best alternative to the conventional fuels for the purposes of domestic, water and space heating and some industries in the sunny, arid, and hot areas. In the present study, the performance of an evacuated tube solar heater for water heating for months of February and March was experimentally investigated. This was performed in a hot and arid area (Nasiriya City, South of Iraq). A solar heater with ten evacuated tube solar collectors with a capacity of 100 liter was used in the experiments. Each evacuated tube had a length… More >

  • Open Access

    ARTICLE

    Research on Mixed Logic Dynamic Modeling and Finite Control Set Model Predictive Control of Multi-Inverter Parallel System

    Xiaojuan Lu, Mengqiao Chen, Qingbo Zhang*

    Energy Engineering, Vol.120, No.3, pp. 649-664, 2023, DOI:10.32604/ee.2023.025065 - 03 January 2023

    Abstract Parallel connection of multiple inverters is an important means to solve the expansion, reserve and protection of distributed power generation, such as photovoltaics. In view of the shortcomings of traditional droop control methods such as weak anti-interference ability, low tracking accuracy of inverter output voltage and serious circulation phenomenon, a finite control set model predictive control (FCS-MPC) strategy of microgrid multi-inverter parallel system based on Mixed Logical Dynamical (MLD) modeling is proposed. Firstly, the MLD modeling method is introduced logical variables, combining discrete events and continuous events to form an overall differential equation, which makes… More > Graphic Abstract

    Research on Mixed Logic Dynamic Modeling and Finite Control Set Model Predictive Control of Multi-Inverter Parallel System

  • Open Access

    ARTICLE

    Analysis of Temperature Rise Characteristics and Fatigue Damage Degree of ACSR Broken Strand

    Jun Zhang1, Xiaobin Li1, Long Zhao2,*, Zixin Li1, Shuo Wang1, Pan Yao1, Pengfei Dai2

    Energy Engineering, Vol.120, No.3, pp. 617-631, 2023, DOI:10.32604/ee.2022.024855 - 03 January 2023

    Abstract In this paper, the research on ACSR temperature of broken strand and fatigue damage after broken strand is carried out. Conduct modeling and Analysis on the conductor through Ansoft Maxwell software. The distribution of magnetic force lines in the cross section of the conductor after strand breaking and the temperature change law of the conductor with the number of broken strands are analyzed. A model based on electromagnetic theory is established to analyze the distribution of magnetic lines of force in the cross section of the conductor after strand breaking and the temperature variation law… More >

  • Open Access

    ARTICLE

    Identification Method for Users-Transformer Relationship in Station Area Based on Local Selective Combination in Parallel Outlier Ensembles Algorithm

    Yunlong Ma1, Junwei Niu2,*, Bo Xu3, Xingtao Song2, Wei Huang2, Guoqiang Sun2

    Energy Engineering, Vol.120, No.3, pp. 681-700, 2023, DOI:10.32604/ee.2023.024719 - 03 January 2023

    Abstract In the power distribution system, the missing or incorrect file of users-transformer relationship (UTR) in low-voltage station area (LVSA) will affect the lean management of the LVSA, and the operation and maintenance of the distribution network. To effectively improve the lean management of LVSA, the paper proposes an identification method for the UTR based on Local Selective Combination in Parallel Outlier Ensembles algorithm (LSCP). Firstly, the voltage data is reconstructed based on the information entropy to highlight the differences in between. Then, the LSCP algorithm combines four base outlier detection algorithms, namely Isolation Forest (I-Forest),… More >

  • Open Access

    ARTICLE

    Optimization of Electricity Purchase and Sales Strategies of Electricity Retailers under the Condition of Limited Clean Energy Consumption

    Peng Liao1,*, Hanlin Liu1, Yingjie Wang2, Neng Liao3

    Energy Engineering, Vol.120, No.3, pp. 701-714, 2023, DOI:10.32604/ee.2022.024301 - 03 January 2023

    Abstract In the process of my country’s energy transition, the clean energy of hydropower, wind power and photovoltaic power generation has ushered in great development, but due to the randomness and volatility of its output, it has caused a certain waste of clean energy power generation resources. Regarding the purchase and sale of electricity by electricity retailers under the condition of limited clean energy consumption, this paper establishes a quantitative model of clean energy restricted electricity from the perspective of power system supply and demand balance. Then it analyzes the source-charge dual uncertain factors in the… More > Graphic Abstract

    Optimization of Electricity Purchase and Sales Strategies of Electricity Retailers under the Condition of Limited Clean Energy Consumption

  • Open Access

    ARTICLE

    Electric Vehicle Charging Capacity of Distribution Network Considering Conventional Load Composition

    Pengwei Yang1, Yuqi Cao2, Jie Tan2, Junfa Chen1, Chao Zhang1, Yan Wang1, Haifeng Liang2,*

    Energy Engineering, Vol.120, No.3, pp. 743-762, 2023, DOI:10.32604/ee.2023.024128 - 03 January 2023

    Abstract At present, the large-scale access to electric vehicles (EVs) is exerting considerable pressure on the distribution network. Hence, it is particularly important to analyze the capacity of the distribution network to accommodate EVs. To this end, we propose a method for analyzing the EV capacity of the distribution network by considering the composition of the conventional load. First, the analysis and pretreatment methods for the distribution network architecture and conventional load are proposed. Second, the charging behavior of an EV is simulated by combining the Monte Carlo method and the trip chain theory. After obtaining… More >

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