Shihu Liu, Chunsheng Yang^*, Yingjie Liu

Intelligent Automation & Soft Computing, Vol., , DOI:10.32604/iasc.2023.040818

Abstract Many network presentation learning algorithms (NPLA) have originated from the process of the random walk between nodes in recent years. Despite these algorithms can obtain great embedding results, there may be also some limitations. For instance, only the structural information of nodes is considered when these kinds of algorithms are constructed. Aiming at this issue, a label and community information-based network presentation learning algorithm (LC-NPLA) is proposed in this paper. First of all, by using the community information and the label information of nodes, the first-order neighbors of nodes are reconstructed. In the next, the random walk strategy is improved… More >

Yongguo Li^1,2, Caiyin Xu^1,2,*, Can Qin^1,2, Dingjian Zheng^1,2

FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.044804

Abstract The so-called ORC (Organic Rankine Cycle) heat recovery technology has attracted much attention with regard to medium and low temperature waste heat recovery. In the present study, it is applied to a Tesla turbine. At the same time, the effects of the disc speed, diameter and inter-disc gap on the internal flow field and output power of the turbine are also investigated by means of CFD (Computational Fluid Dynamics) numerical simulation, by which the pressure, velocity, and output efficiency of the internal flow field are obtained under different internal and external conditions. The highest efficiency (66.4%) is obtained for a… More >

PEI QIN^#, MIAO LIU^#, XIN WANG, JIANHUA MA^*

BIOCELL, Vol., , DOI:10.32604/biocell.2023.045640

Abstract Background: L-dopa (Levodopa) is well known for managing PD (Parkinson’s disease); however, its prolonged use caused dyskinesia (LID). Due to the varied presentation of LID, effective treatment options are scarce. Flavonoids reported their neuroprotective activity by ameliorating acetylcholinesterase, monoamine oxidase, and neuroinflammation. Kaempferol is another flavonoid bearing these potentials. Aim: To evaluate neuroprotective activity of kaempferol in dyskinetic rats. Methods: PD was developed in Sprague-Dawley rats by injecting combination of L-ascorbic acid (10 µL) + 6-OHDA (12 µg) in medial forebrain bundle to induce neuronal damage in substantial nigra (SNr). LID was induced by administrating combination of L-dopa (20 mg/kg)… More > Graphic Abstract

VAN THI TUONG NGUYEN^1,2, KHUONG DUY PHAM^1,2,3, HUONG THI QUE CAO^1,2, PHUC VAN PHAM^1,2,*

BIOCELL, Vol., , DOI:10.32604/biocell.2023.043664

Abstract Mesenchymal stem cells (MSCs) have been proposed in regenerative medicine, especially for angiogenic purposes, due to their potential to self-renew, differentiate, and regulate the microenvironment. Peripheral vascular diseases, which are associated with reduced blood supply, have been treated but not cured. An effective therapy is to recover blood supply via vessel regeneration in the affected area, and MSCs appear to be promising for such conditions. Several studies aimed to explore the role of MSCs in performing angiogenesis and have revealed numerous potential methods to enhance MSC capacity in vessel formation. Efforts have been made to modify standard MSCs to optimize… More > Graphic Abstract

QIOU GU¹, CHUILIN LAI¹, XIAO GUAN¹, JING ZHU², TIAN ZHAN¹, JIANPING ZHANG^1,*

BIOCELL, Vol., , DOI:10.32604/biocell.2023.028336

Abstract Objectives: Colorectal cancer (CRC) is a serious threat to human health worldwide. Oxaliplatin is a platinum analog and is widely used to treat CRC. However, resistance to oxaliplatin restricts its effectiveness and application while its target recognition and mechanism of action also remain unclear. Therefore, we aimed to develop an oxaliplatin-resistant prognostic model to clarify these aspects. Methods: We first obtained oxaliplatin-resistant and parental cell lines, and identified oxaliplatin-resistant genes using RNA sequencing (RNA-seq) and differential gene analysis. We then acquired relevant data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. Cox regression and Least Absolute… More > Graphic Abstract

Xiufeng Zhu^1,2, Jingying Wang^1,*

FDMP-Fluid Dynamics & Materials Processing, Vol., , DOI:10.32604/fdmp.2023.045260

Abstract

SR-AOP (sulfate radical advanced oxidation process) is a novel water treatment method able to eliminate refractory organic pollutants. Hydrodynamic cavitation (HC) is a novel green technology, that can effectively produce strong oxidizing sulfate radicals. This paper presents a comprehensive review of the research advancements in these fields and a critical discussion of the principal factors influencing HC-enhanced SR-AOP and the mechanisms of synergistic degradation. Furthermore, some insights into the industrial application of HC/PS are also provided. Current research shows that this technology is feasible at the laboratory stage, but its application on larger scales requires further understanding and exploration. In… More > Graphic Abstract

Wanxiu Zhu^*

Psycho-Oncologie, Vol., , DOI:10.32604/po.2023.046593

Abstract Exploring the relationship between social support and the mental health of cancer patients is a vital endeavor for enhancing mental well-being. The objective of this study was to explore the relationship between social support and psychological well-being in cancer patients and to provide new empirical evidence for psychological improvement in cancer patients. This research holds significant practical implications for optimizing China’s public health system and strengthening the development of a healthy China. Using data from the 2018 China Health and Retirement Longitudinal Study (CHARLS) database, we empirically examined the influence of social support on the mental health of cancer patients.… More >

JUNZHE YI^1,#, BINBIN LI^2,#, XIAOMIN YIN³, LINGRUI LIU¹, CAILU SONG¹, YING ZHAO⁴, MANBO CAI³, HAILIN TANG¹, DONG CHEN^4,*, NING LYU^1,*

Oncology Research, Vol., , DOI:10.32604/or.2024.047524

Abstract Circular RNAs (circRNAs) have been recognized as pivotal regulators in tumorigenesis, yet the biological functions as well as molecular mechanisms of the majority of circRNAs in hepatocellular carcinoma (HCC) remain elusive. We sought to unveil the expression profile and biological role of circMYBL2 in HCC. Initial microarray analyses were conducted to probe the expression profile of circMYBL2 in HCC cells, and qRT‒PCR analysis was then performed in HCC cell lines and tissues, revealing significant upregulation of circMYBL2. Subsequent experiments were conducted to evaluate the biological function of circMYBL2 in HCC progression. Furthermore, bioinformatics analysis, qRT‒PCR analysis, luciferase reporter assays, and… More >

JIANBO ZHOU^1,2,3, FENG WAN^2,4, BIN XIAO⁵, XIN LI¹, CHENG PENG^2,*, FU PENG^1,3,*

Oncology Research, Vol., , DOI:10.32604/or.2023.044775

Abstract Breast and lung cancers are the leading causes of mortality and most frequently diagnosed cancers in women and men, respectively, worldwide. Although the antitumor activity of chalcones has been extensively studied, the molecular mechanisms of isoliquiritigenin analog 2', 4', 4-trihydroxychalcone (metochalcone; TEC) against carcinomas remain less well understood. In this study, we found that TEC inhibited cell proliferation of breast cancer BT549 cells and lung cancer A549 cells in a concentration-dependent manner. TEC induced cell cycle arrest in the S-phase, cell migration inhibition in vitro, and reduced tumor growth in vivo. Moreover, transcriptomic analysis revealed that TEC modulated the activity… More > Graphic Abstract

Shize Zhi^1,2,*

International Journal of Mental Health Promotion, Vol., , DOI:10.32604/ijmhp.2024.049077

Abstract This article has no abstract. More >