Rumeng Li¹, Guozhu Zhan², Qi Ma¹, Yunhe Yang¹, Xiaoyun Liu^1,*, Yitong Zhang¹, Qixin Zhuang¹

Journal of Renewable Materials, Vol.9, No.12, pp. 2093-2117, 2021, DOI:10.32604/jrm.2021.015827

Abstract To explore the influence of substituent groups on thermally induced curing, eight new bio-based benzoxazines containing different substituent groups with different electron negativity and volumes were synthesized. The thermal curing of these bio-based benzoxazines was studied in detail. Combined with the curing reaction kinetics, simulation and calculation of Highest Occupied Molecular and Lowest Unoccupied Molecular values, the spatial and electronic effects of different substituent groups on the curing of benzoxazine was explored. It was found that when the substituent was located at the position directly connected to the N atom, the steric hindrance effect of the group was dominant. When… More > Graphic Abstract

Qionglin Luo¹, Mingliang Wang², Hui Zhang¹, Yuejun Ouyang¹, Hongwei Lin¹, You Shu^1,*, Shengpei Su^1,2,*

Journal of Renewable Materials, Vol.9, No.12, pp. 2067-2076, 2021, DOI:10.32604/jrm.2021.016255

Abstract Poly(L-lactic acid) (PLLA) is a thermoplastic material with complete degradability, high biocompatibility and excellent mechanical properties. It can replace petroleum-based polymers are currently being used in the fields of packaging, agriculture, textiles, medical and so on. However, PLLA’s extremely flammability greatly limits its wider application. An bio-based flame retardant L-APP/PLLA composites was prepared by melt blending of the L-APP and PLLA. The morphology, impact properties, thermal properties and flame retardant properties of composites were investigated by field emission scanning electron microscope (SEM), impact tester, differential scanning calorimeter (DSC), thermogravimetric analyzer (TGA), limiting oxygen indexer (LOI) and horizontalvertical burning tester. The… More > Graphic Abstract

Madhumitha Kedhari Sundaram¹, Abdulmajeed G. Almutary², Shafiul Haque³, Faheem SM¹, Arif Hussain^1,*

Oncologie, Vol.23, No.2, pp. 269-277, 2021, DOI:10.32604/Oncologie.2021.016002

Abstract Cervical cancer is the neoplasm of the uterine cervix in women, which is highly preventable. With the advent of vaccination against HPV infection, a gradual decline in the incidence of cervical cancer cases has been observed in developing countries. The developing nations bear the brunt of cervical cancer incidence due to low acceptance of vaccination. This survey-based study was designed to assess the awareness and opinions of female university students regarding human papilloma virus, vaccination and cervical cancer. A survey questionnaire was distributed among female expatriate students (18 to 26 years of age) of a private university. The survey sought… More >

Chunya Hu, Yu He^*

Oncologie, Vol.23, No.2, pp. 241-250, 2021, DOI:10.32604/Oncologie.2021.015828

Abstract Objective: The aim of the present study was to investigate the anti-tumor effects of formononetin on human nonsmall cell lung cancer (NSCLC) and its potential molecular mechanism. Methods: A549 cells were treated with different concentrations of formononetin, then detected the cell proliferation, apoptosis and the expression of HIPK2 respectively by MTT assay, flow cytometry analysis and RT-qPCR. Then the interaction between miR- 27a-3p and its target gene HIPK2 was verified through luciferase reporter assay. The expression of miR-27a- 3p, HIPK2, and p53 was detected after being treated with different formononetin concentrations by RT-qPCR and western blot. Results: The results showed… More >

Yongtao Yu, Guangdong Zou^*

Oncologie, Vol.23, No.2, pp. 293-301, 2021, DOI:10.32604/Oncologie.2021.015520

Abstract Objective: The purpose was to explore the value of multi-slice spiral CT (MSCT) multiplanar reconstruction technique in the diagnosis and clinicopathological analysis of gastrointestinal lymphoma (GIL). Methods: 82 GIL patients treated in our hospital from February 2018 to February 2019 were selected as the experimental group of this study, and 82 patients with other gastrointestinal tumors diagnosed by pathology during the same period were selected as the control group. Both groups of patients were scanned by MSCT and analyzed by multiplanar reconstruction technique to compare the diagnostic results and clinicopathological indexes of the two groups. Results: The diagnostic accuracy of… More >

Peng Wang, Haiyang Zhang, Zilian Cui, Xunbo Jin^*, Dong Zhang^*

Oncologie, Vol.23, No.2, pp. 259-268, 2021, DOI:10.32604/Oncologie.2021.015503

Abstract Urothelial carcinoma of bladder (UCB) is a common urological malignancy in the world, but its progression mechanism remains unclear. MiR-612 was found as an anti-tumor factor in multiple types of cancer, while few studies have revealed its functions in UCB cells. Based on this, UCB cells such as HTB-9 and HTB-4, and normal urothelial of bladder cells such as SV-Huc1, were used as subjects in this study. Western blot, qRTPCR, CCK-8 assay and transwell assay were used to assess functions of miR-612 in UCB cells. The database, miRWalk, was used to search for potential targets of miR-612, and dual-luciferase reporter… More >

R. J. Salmon^1,2,*

Oncologie, Vol.23, No.2, pp. 173-176, 2021, DOI:10.32604/Oncologie.2021.017020

Abstract This article has no abstract. More >

Xiaofan Deng^1,2, Yamei Yang^2,3, Xianfeng Gan^2,3, Gang Wu^2,3,*

Oncologie, Vol.23, No.2, pp. 251-258, 2021, DOI:10.32604/Oncologie.2021.016900

Abstract microRNA-422a (miR-422a) is downregulated in many hematopoietic tumors and solid tumors including hepatocellular carcinoma. We previously demonstrated that hepatitis B virus X protein (HBx) downregulated expression of miR-422a in HCC cell line HepG2 in vitro. However, we explore the mechanisms underlying this action. Forkhead box proteins (FOX) G1/Q1/E1 are known to negatively regulate miR-422a expression, and this prompted us to determine whether HBx suppresses miR-422a expression via activation of FOXG1/Q1/E1. The relationship between FOXG1/Q1/E1 and miR-422a in HepG2 cells stably expressing HBx was assessed with qRT-PCR. The correlation between HBx and FOXG1/Q1/E1 was determined with qRT-PCR and western blot in… More >

Yu Xiao¹, Peng Zhou², Yizi Zheng¹, Chang Zheng¹, Guowen Liu¹, Weixiang Liu^3,*

Oncologie, Vol.23, No.2, pp. 219-228, 2021, DOI:10.32604/Oncologie.2021.016480

Abstract The elevation for lateral lymph node metastasis (LLNM) plays an important role in therapeutic decision-making for thyroid carcinoma. A reliable forecasting model for LLNM in patients with papillary thyroid micro-carcinoma (PTMC) is needed, using clinicopathological characteristics. A total of 576 PTMC patients with suspicious lateral cervical lymph node (II, III, IV or V region) metastasis and known clinicopathological variables were randomly collected at Shenzhen Second People’s Hospital. Cervical lymph node status of every patient was assessed by ultrasonography (US). The patients in this cohort study underwent thyroidectomy and lateral neck lymph node dissection. Univariate analysis and logistic regression analysis were… More >

Hongyan Ai^1,*, Yan Wang², Hongmei Gu²

Oncologie, Vol.23, No.2, pp. 185-193, 2021, DOI:10.32604/Oncologie.2021.016420

Abstract Objective: To explore the effect of the cluster nursing mode combined with blood pressure regulation on the surgical tolerance of patients with esophageal cancer and hypertension. Methods: The clinical data of 86 patients with esophageal cancer and hypertension treated in our hospital (February 2016–February 2017) were retrospectively analyzed. The patients were randomly split into research group and reference group, with 43 cases in each group. The reference group received routine nursing, while the research group received cluster nursing combined with blood pressure regulation. The SBP, DBP and heart rates at D1 (at admission), D2 (2 h before surgery) and D3… More >