Jaber Almutairi¹, Mohammad Aldossary^2,*

Computer Systems Science and Engineering, Vol.41, No.2, pp. 611-624, 2022, DOI:10.32604/csse.2022.018112

Abstract The Internet of Things (IoT) has recently become a popular technology that can play increasingly important roles in every aspect of our daily life. For collaboration between IoT devices and edge cloud servers, edge server nodes provide the computation and storage capabilities for IoT devices through the task offloading process for accelerating tasks with large resource requests. However, the quantitative impact of different offloading architectures and policies on IoT applications’ performance remains far from clear, especially with a dynamic and unpredictable range of connected physical and virtual devices. To this end, this work models the performance impact by exploiting a… More >

Sardar Zafar Iqbal, Hina Gull^*, Saqib Saeed, Madeeha Saqib, Mohammed Alqahtani, Yasser A. Bamarouf, Gomathi Krishna, May Issa Aldossary

Computer Systems Science and Engineering, Vol.41, No.2, pp. 461-477, 2022, DOI:10.32604/csse.2022.017003

Abstract Modern human life is heavily dependent on computing systems and one of the core components affecting the performance of these systems is underlying operating system. Operating systems need to be upgraded to match the needs of modern-day systems relying on Internet of Things, Fog computing and Mobile based applications. The scheduling algorithm of the operating system dictates that how the resources will be allocated to the processes and the Round Robin algorithm (RR) has been widely used for it. The intent of this study is to ameliorate RR scheduling algorithm to optimize task scheduling. We have carried out an experimental… More >

R. Reena Roy^*, G. S. Anandha Mala

Computer Systems Science and Engineering, Vol.41, No.2, pp. 677-688, 2022, DOI:10.32604/csse.2022.016620

Abstract Pancreatic cancer is one of the deadliest cancers, with less than 9% survival rates. Pancreatic Ductal Adeno Carcinoma (PDAC) is common with the general public affecting most people older than 45. Early detection of PDAC is often challenging because cancer symptoms will progress only at later stages (advanced stage). One of the earlier symptoms of PDAC is Jaundice. Patients with diabetes, obesity, and alcohol consumption are also at higher risk of having pancreatic cancer. A decision support system is developed to detect pancreatic cancer at an earlier stage to address this challenge. Features such as Mean Hue, Mean Saturation, Mean… More >

Yu Sun¹, Yi Ding^2,*, Junyi Jiang³, Vincent G. Duffy⁴

Computer Systems Science and Engineering, Vol.41, No.2, pp. 781-794, 2022, DOI:10.32604/csse.2022.016387

Abstract Mental workload is considered to be strongly linked to human performance, and the ability to measure it accurately is key for balancing human health and work. In this study, brain signals were elicited by mental arithmetic tasks of varying difficulty to stimulate different levels of mental workload. In addition, a finite impulse response (FIR) filter, independent component analysis (ICA), and multiple artifact rejection algorithms (MARAs) were used to filter event-related potentials (ERPs). Then, the data consisting of ERPs, subjective ratings of mental workload, and task performance, were analyzed through the use of variance and Spearman’s correlation during a simulated computer… More >

EJDER SAYLAV BORA^1,*, MüMIN ALPER ERDOĞAN², BAHATTIN ÖZKUL³, İBRAHIM HALIL SEVER⁴, İBRAHIM SÖĞÜT⁵, CANAN HÜRDAĞ⁶, OYTUN ERBAŞ⁷

BIOCELL, Vol.46, No.2, pp. 433-439, 2022, DOI:10.32604/biocell.2022.018510

Abstract Purpose: Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known anti-inflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light its effect and underlying mechanism in acute lung injury (ALI). Method: 28 wistar albino rats were divided into 4 groups. Sepsis model is performed by the feces intraperitoneal-injection procedure (FIP). Results: TNF-a, CRP, IL-6, IL 1-Beta, lactic acid, and MDA values were significantly decreased in the FIP+digitoxin group compared to the FIP+Saline group. When the same groups were examined, histological improvements such as… More >

KATARINA BARALIć^1,*, KATARINA ŽIVANčEVIć¹, DRAGICA BoŽIĆ¹, DANYEL JENNEN², ALEKSANDRA BUHA DJORDJEVIC¹, EVICA ANTONIJEVIć MILJAKOVIć¹, DANIJELA ĐUKIć-ĆOSIć¹

BIOCELL, Vol.46, No.2, pp. 519-533, 2022, DOI:10.32604/biocell.2022.018271

Abstract This in silico toxicogenomic study aims to explore the relationship between phthalates and bisphenol A (BPA) co-exposure and obesity, as well as its comorbid conditions, in order to construct a possible set of genomic biomarkers. The Comparative Toxicogenomics Database (CTD; http://ctd.mdibl.org) was used as the main data mining tool, along with GeneMania (https://genemania.org), ToppGene Suite (https://toppgene.cchmc.org) and DisGeNET (http://www.disgenet.org). Among the phthalates, bis(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP) were chosen as the most frequently curated phthalates in CTD, which also share similar mechanisms of toxicity. DEHP, DBP and BPA interacted with 84, 90 and 194 obesity-related genes/proteins, involved in… More >

RAFAEL MORENO-GÓMEZ-TOLEDANO^1,*, MARíA I. ARENAS², ESPERANZA VÉLEZ-VÉLEZ³, RICARDO J. BOSCH¹

BIOCELL, Vol.46, No.2, pp. 305-308, 2022, DOI:10.32604/biocell.2022.017894

Abstract Bisphenol A (BPA) is a xenoestrogen known for its implications for the endocrine systems and several other organs, including the kidneys. Recent renal studies have shown that BPA can induce alterations of the cytoskeleton and cell adhesion mechanisms such as a podocytopathy with proteinuria and hypertension, alterations involved in the progression of renal diseases. These data and the fact that BPA is known to be present in the urine of almost the entire population strongly suggest the critical need to reevaluate BPA exposures considered safe. More >

AMOURA M. ABOU-EL-NAGA¹, SHAKER A. MOUSA², FAYEZ ALTHOBAITI³, EMAN FAYAD^3,*, ENGY S. FAHIM¹

BIOCELL, Vol.46, No.2, pp. 535-545, 2022, DOI:10.32604/biocell.2022.017739

Abstract Testicular damage is one of the most hazardous effects as it’s associated with azoospermia. Busulfan (Bu) is a highly toxic chemotherapeutic drug that affects testis. Thirty male Swiss albino mice divided into six groups of 5 animals each. Control (oral 0.9% saline daily for 75 days); Mel (20 mg/kg/day orally for 30 days); ZnO NPs (5 mg/kg/day i.p. for 30 days); BU (single i.p. injection of 40 mg/kg and then left for 45 days); BU + Mel (single 40 mg/kg dose of BU and left for 45 days followed by 20 mg/kg/day Mel for 30 days); BU + ZnO NPs… More >

PAOLA GRIMALDI^*

BIOCELL, Vol.46, No.2, pp. 301-304, 2022, DOI:10.32604/biocell.2022.017588

Abstract Cannabis is the most widely used drug in the Western societies particularly among adolescent and young adults. Epidemiological studies demonstrate that men use cannabis more frequently than women with higher risk in developing cannabis-related disorders. Although the direct adverse effects of cannabis on male reproductive functions have been studied both in humans and animal models, the possible long-term risks for the health of the users and their offspring are still an area of active research. More >

HUIZE CHEN^1,2,*, XINGTIAN JIA^1,2, HAIYAN RAN^1,2, JINGRONG NIU^1,2, MEITING DU¹

BIOCELL, Vol.46, No.2, pp. 559-565, 2022, DOI:10.32604/biocell.2022.017437

Abstract As an allohexaploid plant, common wheat has a complex gene structure, making it difficult to study its gene function. Virus-induced gene silencing (VIGS) is an important tool for the rapid analysis of plant gene function. In this study, the gene silencing system, namely, barley stripe mosaic virus (BSMV)-VIGS induced by BSMV was used to silence the wheat phytoene desaturase (TaPDS) and actin depolymerization factor (TaADF7) genes and determine the effect of gene silencing on wheat. TaPDS was used as an indicator gene to determine the feasibility of VIGS system, while TaADF7 was used as a test gene to determine its… More >