F. Guillemin, F. Marchal, M. Geffroy

Oncologie, Vol.21, No.1, pp. 22-28, 2019, DOI:10.3166/onco-2019-0028

Abstract Purpose: Assessment of a second surgical conservative treatment (T) [N = 41] compared to total mastectomy (M) [N = 93] for ipsilateral breast tumor recurrence after initial breast conserving surgery in a retrospective study of 134 patients. Results: Five years global survival was 82.5% in each group. No statistical difference for the specific survival and survival without metastasis. The 5 years local control was 92.9% in group M and 66.2% in group T (RR = 4.48). Lymphovascular invasion (LVI), multifocal tumors, and clinical symptoms of the recurrence are pejorative factors for survival. Over the 134 patients, 25 have preserved their… More >

G. Oldrini, P. Henrot, F. Marchal

Oncologie, Vol.21, No.1, pp. 17-21, 2019, DOI:10.3166/onco-2019-0033

Abstract Breast cancer is the first female cancer in France and its early detection is essential. Breast MRI is an element of choice in its diagnosis but it has high direct and indirect costs because of its duration which slows down its wider use. Given its elements, the use of an abbreviated protocol develops to overcome these disadvantages. Early literature data suggests that this faster examination also allows for a shorter interpretation time. In addition, the sensitivity and specificity of the examination are not inferior to that of the complete protocol. This article explains the new concept and its interest, compares… More >

J. Boudier, G. Oldrini, C. Barlier, A. Lesur

Oncologie, Vol.21, No.1, pp. 11-16, 2019, DOI:10.3166/onco-2019-0034

Abstract When a breast cancer is diagnosed, the quality of the evaluation before treatment is essential to guide the therapeutic decision. The staging axillary is necessary because it estimates the regional extension of the disease, which makes it a paramount prognosis factor. Some different preoperative medical imaging can reveal metastasis axillary nodes. However, the axillary ultrasound remains the reference imaging and it also leads the biopsies too. Since theACOSOG-Z0011 trial, we are facing a therapeutic deescalation in the axillary surgery. According to recent results, we can note that the position of the axillary imaging is more and more important. The purpose… More >

S. Dejust

Oncologie, Vol.21, No.1, pp. 5-10, 2019, DOI:10.3166/onco-2019-0031

Abstract Axillary evaluation is a major step in the initial staging of breast cancer. Ultrasound guided biopsy is currently recommended in first-line. MRI and 18FDG PET/CT are useful in axillary lymph node evaluation. Imaging sensitivities and specificities are globally identical and their combination allows obtaining the best performances. Currently, sentinel node technique is essential in case of T1-T2 N0 mammary tumors and in case of suspected lymph node adenopathy with negative cytopuncture or microbiopsy.


Résumé
L’exploration préthérapeutique axillaire est une étape majeure du bilan initial du cancer du sein. L’échographie associée à un prélèvement est actuellement recommandée en première intention. L’IRM et la… More >

A. Lesur, F. Guillemin

Oncologie, Vol.21, No.1, pp. 3-4, 2019, DOI:10.3166/onco-2019-0032

Abstract This article has no abstract. More >

H. Magdelénat, J. Rouessé

Oncologie, Vol.21, No.1, pp. 1-2, 2019, DOI:10.3166/onco-2019-0022

Abstract This article has no abstract. More >

Jean-Philippe Metges^1,*, Daniel Serin², Xavier Troussard^3,4,5, Jean-Yves Blay⁶, Mario Campone⁷, Nicolas Isambert⁸, Tristan Montier^9,10, Nadine Houédé^11,12, Denis Frank¹³

Oncologie, Vol.23, No.1, pp. 1-2, 2021, DOI:10.32604/Oncologie.2021.016042

Abstract This article has no abstract. More >

Thierry Levy^1,*, Joël Castelli², Morgane Kermarrec³, Jean-Philippe Metges⁴

Oncologie, Vol.23, No.1, pp. 3-38, 2021, DOI:10.32604/Oncologie.2021.016041

Abstract Introduction: For several centuries, scientists such as Avicenna have been trying to understand the processes involved in the spread of epidemics. Isolation instructions appeared during the black plague. Magistrates and crisis managers manage the protection of all populations. Nowadays, regional health agencies regulate the provision of health care even in times of health crisis. Methods: The creation of the COVID and Cancer regional committee organized and run by the ARS and the Oncobretagne regional cancer network enables exchanges between oncology health professionals. This committee relays information to national representatives: Ministry, INCa (National Cancer Institute) who adjust their recommendations to cancer… More >

Delphine Déniel Lagadec^1,2,*, Laurence Guen^1,2, Fabienne Le Goc Le Sager¹, Sandrine Estivin^1,3, Christophe Perrin^1,4

Oncologie, Vol.23, No.1, pp. 39-46, 2021, DOI:10.32604/Oncologie.2021.015985

Abstract Since October 2020, the COVID-19 epidemic has affected the care of patients in the field of oncology/hematology in the public and private establishments. The “Unité de coordination en onco-geriatrie région Bretagne” (coordinating unit in onco-geriatrics of the Brittany region) has wished to have a survey with specialists in cancerology so as to make an inventory of the care given to cancer patients aged over 75 in the region. An inquest was made in the course of October 2020, following the first lock down, with 24 specialists. 67% of them feel they lack in clear orders/institutional prescriptions related with this epidemic.… More >

Yuan Liu^1,2,#, Yun Jia³, Bing Zhang², Anwen Liu^1,*

Oncologie, Vol.23, No.1, pp. 61-72, 2021, DOI:10.32604/Oncologie.2021.015906

Abstract Gastric cancer (GC) is the most common digestive system malignant tumor and second most common cause of cancer-related death. Even for the early gastric cancer, after radical operation, perioperative and postoperative chemotherapy the recurrence and metastasis are also high. 5-year overall survival of all GC patients is only 10–15%. Chemo-resistance still poses a major obstacle to successful treatment of GC. The aberrant expression of TUG1 (Taurine Upregulated Gene 1) was closely related to chemo-resistance and metastasis in many cancers. Here we over-expressed TUG1 in GC cell line SGC-7901 and MGC-803. We compared the migration ability and sensitivity of cisplatin (CDDP),… More >