Dominique Vervoort^1,2,3,*, Amy Verstappen³, Sreehari Madhavankutty Nair⁴, Chong Chin Eu⁵, Bistra Zheleva^3,6

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.049814

Abstract This article has no abstract. More >

Ghazi A. Alshumrani^*

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.049401

Abstract Objective: Coronary artery anatomical variations and anomalies are an important topic due to their potential clinical manifestations. This study aims to investigate the prevalence of coronary artery anatomical variations and anomalies in symptomatic patients with coronary computed tomography angiography (CCTA). Methods: This is a retrospective study that included all symptomatic patients who had CCTA in a tertiary care hospital in Saudi Arabia during a period of seven years. Results: The total number of included patients was 507 (60% males) with a mean age of 57.4 years. Approximately 41% had luminal stenoses, averaging 49.7%. The total number of patients with coronary… More >

Yuan Ren¹, Yingxian Sun¹, Zhiguang Yang², Yanli Chen^1,*

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.047930

Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a chronic, progressive, debilitating, and life-threatening complication of pulmonary embolism (PE). Recent technological advances have permitted various treatment options for the treatment of CTEPH, including surgery, angioplasty, and medical treatment, depending on the location and characteristics of lesions. Pulmonary endarterectomy (PEA) is the treatment of choice for CTEPH, as it offers excellent long-term outcomes and a high probability of recovery. Moreover, various medical and interventional therapies are currently being developed for patients with inoperable CTEPH. This review mainly summarizes the current treatment approaches of CTEPH, offering more options for specialist physicians to, thus, better… More >

Yang Wang^#, Xun Yang^#, Mingtang Ye, Yuhang Zhao, Runsen Chen, Min Da, Zhiqi Wang, Xuming Mo, Jirong Qi^*

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.048314

Abstract Congenital heart disease (CHD), the most prevalent congenital ailment, has seen advancements in the “dual indicator” screening program. This facilitates the early-stage diagnosis and treatment of children with CHD, subsequently enhancing their survival rates. While cardiac auscultation offers an objective reflection of cardiac abnormalities and function, its evaluation is significantly influenced by personal experience and external factors, rendering it susceptible to misdiagnosis and omission. In recent years, continuous progress in artificial intelligence (AI) has enabled the digital acquisition, storage, and analysis of heart sound signals, paving the way for intelligent CHD auscultation-assisted diagnostic technology. Although there has been a surge… More > Graphic Abstract

Gustavo Cruz^1,*, Santiago Pedroza², Juan F. Vélez³, Jessica Largo², Juan F. Tejada⁴, Jorge H. Mejía-Mantilla⁵

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.044244

Abstract Background: Failure to rescue has been an effective quality metric in congenital heart surgery. Conversely, morbidity and mortality depend greatly on non-modifiable individual factors and have a weak correlation with better-quality performance. We aim to measure the complications, mortality, and risk factors in pediatric patients undergoing congenital heart surgery in a high-complexity institution located in a middle-income country and compare it with other institutions that have conducted a similar study. Methods: A retrospective observational study was conducted in a high-complexity service provider institution, in Cali, Colombia. All pediatric patients undergoing any congenital heart surgery between 2019 and 2022 were included.… More >

Camden L. Hebson^1,*, Kyle Bliton², Amr Y. Hammouda¹, Kaitlyn Barr³, W. Hampton Gray⁴, Mohini Gunnett², Waldemar F. Carlo¹

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.048871

Abstract D-transposition of the great arteries (d-TGA) is surgically repaired with the arterial switch operation (ASO) with excellent results, however short and long-term morbidities still develop including neurocognitive delay. Clinically significant central sleep apnea is uncommon in non-premature infants, but when present indicates immature autonomic control of respiration likely due to a neurologic disorder. We report the unanticipated finding of central sleep apnea in four-term neonates with d-TGA after uncomplicated ASO, with the short-term complication of delayed hospital discharge and long-term concerns regarding this early marker of brain immaturity and its hindrance to normal development. Within this report, we will review… More >

Michael A. Rebolledo^1,*, Jane S. Yao², Jason N. Johnson¹, Umar S. Boston³, Benjamin R. Waller¹

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.046638

Abstract We describe a 63-year-old male who appears to have undergone an early form of the arterial switch operation for D-transposition of the great arteries performed in the mid-1960s. We review the clinical and imaging data that support our conclusion. He had a diagnostic cardiac catheterization which demonstrated severe pulmonary hypertension responsive to epoprostenol and oxygen. Our case may represent one example of the experimental surgical work done prior to Dr. Adibe Jatene’s description of the first successful arterial switch performed in 1975. More >

Fu Guan^1,*, Matthias Gass², Florian Berger², Heiko Schneider¹, Firat Duru^1,3, Thomas Wolber^1,3,*

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.047266

Abstract Aims: Although the application of ultrasound-guided vascular puncture and Z-stitch hemostasis to manage femoral access has been widely utilized, there is limited data on this combined application in adult congenital heart disease (ACHD) patients undergoing electrophysiological (EP) procedures. We sought to evaluate the safety and efficacy of ultrasound-guided puncture and postprocedural Z-stitch hemostasis for ACHD patients undergoing EP procedures. Methods and Results: The population of ACHD patients undergoing transfemoral EP procedures at the University of Zurich Heart Center between January 2019 and December 2022 was observed and analyzed. During the study period, femoral access (left/right, arterial/venous) was performed under real-time… More >

Sipawath Khamplod^1,2, Yodying Kaolawanich^1,2, Khemajira Karaketklang³, Nithima Ratanasit^1,2,*

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.048631

Abstract Background: Atrial septal defect (ASD) is a common form of adult congenital heart disease that can lead to long-term adverse outcomes if left untreated. Early closure of ASD has been associated with excellent outcomes and lower complication rates. However, there is limited evidence regarding the prognosis of ASD closure in older adults. This study aims to evaluate the mortality rates in older ASD patients with and without closure. Methods: A retrospective cohort study was conducted on patients aged 40 years or older with ASD between 2001 and 2017. Patients were followed up to assess all-cause mortality. Univariable and multivariable analyses… More > Graphic Abstract

Jae Hong Lee¹, Sungkyu Cho^2,*, Jae Gun Kwak², Hye Won Kwon², Woong-Han Kim², Mi Kyoung Song³, Sang-Yun Lee³, Gi Beom Kim³, Eun Jung Bae³

Congenital Heart Disease, Vol., , DOI:10.32604/chd.2024.045137

Abstract Background: The optimal surgical timing and clinical outcomes of ventricular septal defect (VSD) closure in neonates remain unclear. We aimed to evaluate the clinical outcomes of VSD closure in neonates (age ≤ 30 days). Methods: We retrospectively reviewed 50 consecutive neonates who underwent VSD closure for isolated VSDs between August 2003 and June 2021. Indications for the procedure included congestive heart failure/failure to thrive and pulmonary hypertension. Major adverse events (MAEs) were defined as the composite of all-cause mortality, reoperation, persistent atrioventricular block, and significant (≥grade 2) valvular dysfunction. Results: The median age and body weight at operation were 26.0… More >