Naif Al Mudawi^*

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4945-4962, 2024, DOI:10.32604/cmc.2024.048967

Abstract Parkinson’s disease (PD) is a chronic neurological condition that progresses over time. People start to have trouble speaking, writing, walking, or performing other basic skills as dopamine-generating neurons in some brain regions are injured or die. The patient’s symptoms become more severe due to the worsening of their signs over time. In this study, we applied state-of-the-art machine learning algorithms to diagnose Parkinson’s disease and identify related risk factors. The research worked on the publicly available dataset on PD, and the dataset consists of a set of significant characteristics of PD. We aim to apply… More >

ZHILI ZHUO^#, DONGNI ZHANG^#, WENPING LU^*, XIAOQING WU, YONGJIA CUI, WEIXUAN ZHANG, MENGFAN ZHANG

Oncology Research, Vol.32, No.6, pp. 1093-1107, 2024, DOI:10.32604/or.2024.047257

Abstract Breast cancer is the leading cause of cancer-related deaths in women worldwide, with Hormone Receptor (HR)+ being the predominant subtype. Tamoxifen (TAM) serves as the primary treatment for HR+ breast cancer. However, drug resistance often leads to recurrence, underscoring the need to develop new therapies to enhance patient quality of life and reduce recurrence rates. Artemisinin (ART) has demonstrated efficacy in inhibiting the growth of drug-resistant cells, positioning art as a viable option for counteracting endocrine resistance. This study explored the interaction between artemisinin and tamoxifen through a combined approach of bioinformatics analysis and experimental… More > Graphic Abstract

Troy Myers¹, Michael A. Sutton^1,*, Hubert Schreier², Alistair Tofts², Sreehari Rajan Kattil¹

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1263-1298, 2024, DOI:10.32604/cmes.2024.048743

Abstract To compare finite element analysis (FEA) predictions and stereovision digital image correlation (StereoDIC) strain measurements at the same spatial positions throughout a region of interest, a field comparison procedure is developed. The procedure includes (a) conversion of the finite element data into a triangular mesh, (b) selection of a common coordinate system, (c) determination of the rigid body transformation to place both measurements and FEA data in the same system and (d) interpolation of the FEA nodal information to the same spatial locations as the StereoDIC measurements using barycentric coordinates. For an aluminum Al-6061 double edge More >

Brianna Cerrito^1,*, Jamie Xiao¹, Amie DiTomasso¹, Amanda Fialk¹, Jocelyn Bolin²

International Journal of Mental Health Promotion, Vol.26, No.4, pp. 317-323, 2024, DOI:10.32604/ijmhp.2024.047876

Abstract The purpose of the present study is to evaluate the internal consistency and construct validity of a self-report checklist measuring clinical mental health recovery across six key domains: family and relationships, occupation and school, physical health, mental health, spirituality, and social support systems. The Mental Health Recovery Checklist (MHRC) was developed at The Dorm, an intensive outpatient mental health treatment program for young adults in New York, NY, and Washington DC that services individuals between the ages of 18 and 35 years old. The present study is cross-sectional, as data were pulled from clients’ records… More >

Kamolthip Ruckwongpatr^1,#, Chirawat Paratthakonkun^2,#, Usanut Sangtongdee^3,4,*, Iqbal Pramukti⁵, Ira Nurmala⁶, Kanokwan Angkasith⁷, Weena Thanachaisakul⁷, Jatuphum Ketchatturat⁸, Mark D. Griffiths⁹, Yi-Kai Kao^10,*, Chung-Ying Lin^1,5,11,12

International Journal of Mental Health Promotion, Vol.26, No.4, pp. 293-302, 2024, DOI:10.32604/ijmhp.2024.047023

Abstract Background: In recent years, there has been increased research interest in both smartphone addiction and social media addiction as well as the development of psychometric instruments to assess these constructs. However, there is a lack of psychometric evaluation for instruments assessing smartphone addiction and social media addiction in Thailand. The present study evaluated the psychometric properties and gender measurement invariance of the Thai version of the Smartphone Application-Based Addiction Scale (SABAS) and Bergen Social Media Addiction Scale (BSMAS). Method: A total of 801 Thai university students participated in an online survey from January 2022 to More >

JIAN TANG¹, CHENQIANG ZHU¹, YUN CHEN¹, YUNLONG WU¹, MING HE¹, YI ZHOU², MINGHUA XIE^2,*

BIOCELL, Vol.48, No.4, pp. 639-651, 2024, DOI:10.32604/biocell.2024.047562

Abstract Background: The specific impact of sphingolipid metabolism on developing hepatocellular Carcinoma (HCC) remains unclear. This study aims to explore the relationship between sphingolipid metabolism and HCC prognosis, immune response, and drug sensitivity. Methods: Data were obtained from The Cancer Genome Atlas (TCGA)-Hepatocellular Carcinoma (LIHC) and Gene Expression Omnibus (GEO, GSE14520 datasets). 47 sphingolipid metabolism genes were obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. After classifying HCC samples using the Non-negative Matrix Factorization (NMF) clustering method, differentially expressed genes were screened. Then, 8 risk genes were obtained by univariate analysis, survival random forest… More > Graphic Abstract

Thomas Leduc, Xenia Stavropulos-Laffaille, Ignacio Requena-Ruiz

Revue Internationale de Géomatique, Vol.31, No.2, pp. 241-263, 2022, DOI:10.3166/RIG.31.241-263©2022

Abstract The adaptation of public spaces to episodes of intense heat is now a major challenge for cities. With this in mind, this article presents a contribution aimed at delineating and handling the shadows on the ground or in a horizontal plane at a given height, whether it comes from buildings, street furniture or the tree cover. After a comparison with shadows obtained via two reference tools, we present two urban sites that mix shadows of different origins and, in addition, different indicators. The results of the simulations are compared with pyranometric surveys carried out on More >

YANAN MA¹, SHANSHAN WANG^2,*, HUIGUO DING^1,*

BIOCELL, Vol.48, No.3, pp. 463-471, 2024, DOI:10.32604/biocell.2024.048244

Abstract Background: Hepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis and high mortality worldwide. Although cystathionine-gamma-lyase (CSE) plays an important role in the development of multiple tumors, the clinical implication and potential mechanisms of CSE in HCC development remain elusive. Methods: In our study, the CSE expression in HCC was analyzed in Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) datasets and further confirmed by RT-qPCR and immunohistochemistry assays in HCC samples. Furthermore, the associations between CSE expression and HCC malignancy as well as survival were analyzed in GSE14520 and validated… More >

Chili Li¹, Xinxin Zhao², Ziwen Pan³, Ting Yi⁴, Long Qian^5,6,*

International Journal of Mental Health Promotion, Vol.26, No.2, pp. 161-175, 2024, DOI:10.32604/ijmhp.2023.029896

Abstract While a plethora of studies has been conducted to explore demotivation and its impact on mental health in second language (L2) education, scanty research focuses on demotivation in L2 speaking learning. Particularly, little research explores the measures to quantify L2 speaking demotivation. The present two-phase study attempts to develop and validate an English Speaking Demotivation Scale (ESDS). To this end, an independent sample of 207 Chinese tertiary learners of English as a Foreign Language (EFL) participated in the development phase, and another group of 188 Chinese EFL learners was recruited for the validation of the… More >

Siyuan Bi¹, Junfeng Yuan^1,2, Lin Luo^1,2,3,*

International Journal of Mental Health Promotion, Vol.26, No.1, pp. 51-60, 2024, DOI:10.32604/ijmhp.2023.041614

Abstract Purpose: The core component theory of addiction behavior provides a multidimensional theoretical model for measuring social networking addiction. Based on this theoretical model, the Social Networking Addiction Scale (SNAS) was developed. The aim of this study was to test the psychometric properties of the Chinese version of the SNAS (SNAS-C). Methods: This study used a sample of 3383 Chinese university students to conduct confirmatory factor analysis (CFA) to explore the structural validity of the SNAS-C. This study examined the Pearson correlations between the six subscales of the SNAS-C (i.e., salience, mood modification, tolerance, withdrawal symptoms,… More >