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  • Open Access

    ARTICLE

    A New Speed Limit Recognition Methodology Based on Ensemble Learning: Hardware Validation

    Mohamed Karray1,*, Nesrine Triki2,*, Mohamed Ksantini2

    CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 119-138, 2024, DOI:10.32604/cmc.2024.051562 - 18 July 2024

    Abstract Advanced Driver Assistance Systems (ADAS) technologies can assist drivers or be part of automatic driving systems to support the driving process and improve the level of safety and comfort on the road. Traffic Sign Recognition System (TSRS) is one of the most important components of ADAS. Among the challenges with TSRS is being able to recognize road signs with the highest accuracy and the shortest processing time. Accordingly, this paper introduces a new real time methodology recognizing Speed Limit Signs based on a trio of developed modules. Firstly, the Speed Limit Detection (SLD) module uses… More >

  • Open Access

    ARTICLE

    Developing a Model for Parkinson’s Disease Detection Using Machine Learning Algorithms

    Naif Al Mudawi*

    CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 4945-4962, 2024, DOI:10.32604/cmc.2024.048967 - 20 June 2024

    Abstract Parkinson’s disease (PD) is a chronic neurological condition that progresses over time. People start to have trouble speaking, writing, walking, or performing other basic skills as dopamine-generating neurons in some brain regions are injured or die. The patient’s symptoms become more severe due to the worsening of their signs over time. In this study, we applied state-of-the-art machine learning algorithms to diagnose Parkinson’s disease and identify related risk factors. The research worked on the publicly available dataset on PD, and the dataset consists of a set of significant characteristics of PD. We aim to apply… More >

  • Open Access

    ARTICLE

    Reversal of tamoxifen resistance by artemisinin in ER+ breast cancer: bioinformatics analysis and experimental validation

    ZHILI ZHUO#, DONGNI ZHANG#, WENPING LU*, XIAOQING WU, YONGJIA CUI, WEIXUAN ZHANG, MENGFAN ZHANG

    Oncology Research, Vol.32, No.6, pp. 1093-1107, 2024, DOI:10.32604/or.2024.047257 - 23 May 2024

    Abstract Breast cancer is the leading cause of cancer-related deaths in women worldwide, with Hormone Receptor (HR)+ being the predominant subtype. Tamoxifen (TAM) serves as the primary treatment for HR+ breast cancer. However, drug resistance often leads to recurrence, underscoring the need to develop new therapies to enhance patient quality of life and reduce recurrence rates. Artemisinin (ART) has demonstrated efficacy in inhibiting the growth of drug-resistant cells, positioning art as a viable option for counteracting endocrine resistance. This study explored the interaction between artemisinin and tamoxifen through a combined approach of bioinformatics analysis and experimental… More > Graphic Abstract

    Reversal of tamoxifen resistance by artemisinin in ER+ breast cancer: bioinformatics analysis and experimental validation

  • Open Access

    ARTICLE

    Direct Pointwise Comparison of FE Predictions to StereoDIC Measurements: Developments and Validation Using Double Edge-Notched Tensile Specimen

    Troy Myers1, Michael A. Sutton1,*, Hubert Schreier2, Alistair Tofts2, Sreehari Rajan Kattil1

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1263-1298, 2024, DOI:10.32604/cmes.2024.048743 - 20 May 2024

    Abstract To compare finite element analysis (FEA) predictions and stereovision digital image correlation (StereoDIC) strain measurements at the same spatial positions throughout a region of interest, a field comparison procedure is developed. The procedure includes (a) conversion of the finite element data into a triangular mesh, (b) selection of a common coordinate system, (c) determination of the rigid body transformation to place both measurements and FEA data in the same system and (d) interpolation of the FEA nodal information to the same spatial locations as the StereoDIC measurements using barycentric coordinates. For an aluminum Al-6061 double edge More >

  • Open Access

    ARTICLE

    Validity and Reliability of a Mental Health Recovery Checklist for Young Adults

    Brianna Cerrito1,*, Jamie Xiao1, Amie DiTomasso1, Amanda Fialk1, Jocelyn Bolin2

    International Journal of Mental Health Promotion, Vol.26, No.4, pp. 317-323, 2024, DOI:10.32604/ijmhp.2024.047876 - 04 May 2024

    Abstract The purpose of the present study is to evaluate the internal consistency and construct validity of a self-report checklist measuring clinical mental health recovery across six key domains: family and relationships, occupation and school, physical health, mental health, spirituality, and social support systems. The Mental Health Recovery Checklist (MHRC) was developed at The Dorm, an intensive outpatient mental health treatment program for young adults in New York, NY, and Washington DC that services individuals between the ages of 18 and 35 years old. The present study is cross-sectional, as data were pulled from clients’ records… More >

  • Open Access

    ARTICLE

    Validity, Reliability, and Measurement Invariance of the Thai Smartphone Application-Based Addiction Scale and Bergen Social Media Addiction Scale

    Kamolthip Ruckwongpatr1,#, Chirawat Paratthakonkun2,#, Usanut Sangtongdee3,4,*, Iqbal Pramukti5, Ira Nurmala6, Kanokwan Angkasith7, Weena Thanachaisakul7, Jatuphum Ketchatturat8, Mark D. Griffiths9, Yi-Kai Kao10,*, Chung-Ying Lin1,5,11,12

    International Journal of Mental Health Promotion, Vol.26, No.4, pp. 293-302, 2024, DOI:10.32604/ijmhp.2024.047023 - 04 May 2024

    Abstract Background: In recent years, there has been increased research interest in both smartphone addiction and social media addiction as well as the development of psychometric instruments to assess these constructs. However, there is a lack of psychometric evaluation for instruments assessing smartphone addiction and social media addiction in Thailand. The present study evaluated the psychometric properties and gender measurement invariance of the Thai version of the Smartphone Application-Based Addiction Scale (SABAS) and Bergen Social Media Addiction Scale (BSMAS). Method: A total of 801 Thai university students participated in an online survey from January 2022 to More >

  • Open Access

    ARTICLE

    Identification prognostic features related to sphingolipid metabolism and experimental validation of TRIM47 in hepatocellular carcinoma

    JIAN TANG1, CHENQIANG ZHU1, YUN CHEN1, YUNLONG WU1, MING HE1, YI ZHOU2, MINGHUA XIE2,*

    BIOCELL, Vol.48, No.4, pp. 639-651, 2024, DOI:10.32604/biocell.2024.047562 - 09 April 2024

    Abstract Background: The specific impact of sphingolipid metabolism on developing hepatocellular Carcinoma (HCC) remains unclear. This study aims to explore the relationship between sphingolipid metabolism and HCC prognosis, immune response, and drug sensitivity. Methods: Data were obtained from The Cancer Genome Atlas (TCGA)-Hepatocellular Carcinoma (LIHC) and Gene Expression Omnibus (GEO, GSE14520 datasets). 47 sphingolipid metabolism genes were obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. After classifying HCC samples using the Non-negative Matrix Factorization (NMF) clustering method, differentially expressed genes were screened. Then, 8 risk genes were obtained by univariate analysis, survival random forest… More > Graphic Abstract

    Identification prognostic features related to sphingolipid metabolism and experimental validation of TRIM47 in hepatocellular carcinoma

  • Open Access

    ARTICLE

    Bioinformatics analysis and experimental validation of cystathionine-gamma-lyase as a potential prognosis biomarker in hepatocellular carcinoma

    YANAN MA1, SHANSHAN WANG2,*, HUIGUO DING1,*

    BIOCELL, Vol.48, No.3, pp. 463-471, 2024, DOI:10.32604/biocell.2024.048244 - 15 March 2024

    Abstract Background: Hepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis and high mortality worldwide. Although cystathionine-gamma-lyase (CSE) plays an important role in the development of multiple tumors, the clinical implication and potential mechanisms of CSE in HCC development remain elusive. Methods: In our study, the CSE expression in HCC was analyzed in Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) datasets and further confirmed by RT-qPCR and immunohistochemistry assays in HCC samples. Furthermore, the associations between CSE expression and HCC malignancy as well as survival were analyzed in GSE14520 and validated… More >

  • Open Access

    ARTICLE

    Towards Lessening Learners’ Aversive Emotions and Promoting Their Mental Health: Developing and Validating a Measurement of English Speaking Demotivation in the Chinese EFL Context

    Chili Li1, Xinxin Zhao2, Ziwen Pan3, Ting Yi4, Long Qian5,6,*

    International Journal of Mental Health Promotion, Vol.26, No.2, pp. 161-175, 2024, DOI:10.32604/ijmhp.2023.029896 - 08 March 2024

    Abstract While a plethora of studies has been conducted to explore demotivation and its impact on mental health in second language (L2) education, scanty research focuses on demotivation in L2 speaking learning. Particularly, little research explores the measures to quantify L2 speaking demotivation. The present two-phase study attempts to develop and validate an English Speaking Demotivation Scale (ESDS). To this end, an independent sample of 207 Chinese tertiary learners of English as a Foreign Language (EFL) participated in the development phase, and another group of 188 Chinese EFL learners was recruited for the validation of the… More >

  • Open Access

    ARTICLE

    The Social Networking Addiction Scale: Translation and Validation Study among Chinese College Students

    Siyuan Bi1, Junfeng Yuan1,2, Lin Luo1,2,3,*

    International Journal of Mental Health Promotion, Vol.26, No.1, pp. 51-60, 2024, DOI:10.32604/ijmhp.2023.041614 - 05 February 2024

    Abstract Purpose: The core component theory of addiction behavior provides a multidimensional theoretical model for measuring social networking addiction. Based on this theoretical model, the Social Networking Addiction Scale (SNAS) was developed. The aim of this study was to test the psychometric properties of the Chinese version of the SNAS (SNAS-C). Methods: This study used a sample of 3383 Chinese university students to conduct confirmatory factor analysis (CFA) to explore the structural validity of the SNAS-C. This study examined the Pearson correlations between the six subscales of the SNAS-C (i.e., salience, mood modification, tolerance, withdrawal symptoms,… More >

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