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  • Open Access

    REVIEW

    The Effects of Mindfulness-Based Interventions on Symptoms of Mild Traumatic Brain Injury: A Systematic Review

    Qiqi Feng1, Zhijian Huang2, Yanqiu Wang1, Bin Wang1,*

    International Journal of Mental Health Promotion, Vol.26, No.6, pp. 417-428, 2024, DOI:10.32604/ijmhp.2024.049010

    Abstract Mindfulness-based interventions (MBIs) are emerging non-pharmacological treatments for mild traumatic brain injury (mTBI). In this systematic review, the authors aimed to evaluate the potential efficacy of MBIs to provide recommendations for treating patients with mTBI. We searched of the English literature on MBIs for patients with mTBI as of 01 September, 2023, using the PubMed, Web of Science, PsycINFO, and Scopus databases. One author performed data extraction and quality scoring of the included literature according to the proposed protocol, and another conducted the review. The review was not registered. A total of 11 studies met… More >

  • Open Access

    ARTICLE

    Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases

    PING YANG1,2,3, YUANXIANG LAN1,2, ZHONG ZENG1,2, YAN WANG1,2, HECHUN XIA1,2,*

    BIOCELL, Vol.48, No.1, pp. 149-162, 2024, DOI:10.32604/biocell.2023.042367

    Abstract Background: As a form of biological therapy, placenta-derived mesenchymal stem cells (PDMSCs) exhibit considerable promise in addressing the complex pathological processes of traumaticbrain injury (TBI) due to their multi-target and multi-pathway mode of action. Material & Methods: This study investigates the protective mechanisms and benefits of PDMSCs in mitigating the effects of controlled cortical impact (CCI) in rats and glutamate-induced oxidative stress injury in HT22 cells in vitro. Our primary objective is to provide evidence supporting the clinical application of PDMSCs. Results: In the in vivo arm of our investigation, we observed a swift elevation of matrix metalloproteinase-9… More > Graphic Abstract

    Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases

  • Open Access

    ARTICLE

    A Study on the Finite Element Model for Head Injury in Facial Collision Accident

    Bin Yang1,2,3,*, Hao Sun1, Aiyuan Wang1, Qun Wang2

    Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 49-62, 2020, DOI:10.32604/mcb.2019.07534

    Abstract In order to predict and evaluate injury mechanism and biomechanical response of the facial impact on head injury in a crash accident. With the combined modern medical imaging technologies, namely computed tomography (CT) and magnetic resonance imaging (MRI), both geometric and finite element (FE) models for human head-neck with detailed cranio-facial structure were developed. The cadaveric head impact tests were conducted to validate the headneck finite element model. The intracranial pressure, skull dynamic response and skull-brain relative displacement of the whole head-neck model were compared with experimental data. Nine typical cases of facial traffic accidents More >

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