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    ABSTRACT

    Sensing Traction Force Induces Cell-Cell Distant Communications for the Rapid Network Assembly of Airway Smooth Muscle Cells

    Mingxing Ouyang1,*, Zhili Qian1, Yang Jin1, Linhong Deng1

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 65-65, 2019, DOI:10.32604/mcb.2019.06642

    Abstract The collective functions at cell population level rely on cell-cell communications with or without direct contacts [1-3]. The long-range biomechanical force propagating across certain scales far beyond single cell size may reserve the capability to trigger coordinative biological responses within cell population [3-5]. Whether and how cells communicate with each other mechanically in a distant manner remains largely to be explored. Airway smooth muscle (ASM) cells are one crucial component in providing mechanical support and contraction force for the bronchial tubes in respiratory system, whereas the mechanical property of ASM is also associated with asthma… More >

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