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  • Open Access

    ARTICLE

    Ecological Factors Drive the Accumulation of Active Components in Codonopsis pilosula

    Menghan Li1,2,#, Yuhui He1,#, Changning Chen2, Li Liu2, Jia Xu2, Jiahao Cao1,2, Xiaotong Guo1,*, Linlin Dong1,2,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.8, pp. 2575-2591, 2025, DOI:10.32604/phyton.2025.064518 - 29 August 2025

    Abstract Codonopsis pilosula is a major Qi-tonifying medicinal herb, and its active composition is analyzed systematically. However, the relationship between its production origins and commodity specification grades with the active composition of C. pilosula lacks systematic research. This study integrates the HPLC and UV-Vis methodologies to evaluate the quality of C. pilosula from commodity specification grades and different origins, and it explores the correlation between ecological factors and production origins with active components. Here, network pharmacology is used to determine that lobetyolin, syringin, and tangshenoside I have potential efficacy in treating pulmonary fibrosis and oxidative stress. The HPLC and… More >

  • Open Access

    ARTICLE

    Comparison of Apigenin, Quercetin and Kaempferol Accumulation and Total Flavonoid Content in Leaves, Embryogenic Cultures and Cell Suspension Cultures of Parsley (Petroselinum crispum)

    Laura Isabel Arias-Rodríguez1, Martha Alicia Rodríguez-Mendiola2,*, Carlos Arias-Castro2,*, Federico Antonio Gutiérrez Miceli1, Diana Reséndez Pérez3, María Celina Luján Hidalgo1, Juan José Villalobos Maldonado1, Norma Alejandra Mancilla Margalli2

    Phyton-International Journal of Experimental Botany, Vol.92, No.10, pp. 2807-2823, 2023, DOI:10.32604/phyton.2023.030396 - 15 September 2023

    Abstract In recent years, there has been a growing interest in exploring alternative treatments for bone defects. Bone tissue engineering has turned its attention to plant extracts containing osteogenic flavonoids as potential promoters of bone regeneration. In our study, we specifically investigated the extract of Petroselinum crispum, a plant known for its abundance of osteogenic flavonoids such as apigenin, quercetin, and kaempferol. Our objective was to compare the total flavonoid content (TFC) and their accumulation in different sources. We obtained hydrolyzed aqueous extracts from the leaves of parsley plants (grown for 12 weeks in the field), weekly… More >

  • Open Access

    ARTICLE

    Extraction, Antioxidant Activity and Identification of Flavonoids from Root Tubers of Kosteletzkya virginica

    Yu Zai*, Shaohua Liu

    Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 225-236, 2023, DOI:10.32604/phyton.2022.022576 - 06 September 2022

    Abstract Kosteletzkya virginica (K. virginica) is used for revegetation of salt-affected coastal tidal flats and as a raw material of biodiesel. K. virginica root tuber, a biowaste with low economic value, is rich in bioactive compounds. This study aimed to extract and identify flavonoids from K. virginica root tubers. The optimal extraction conditions were 1/25 (w/v) solid/liquid ratio, 40% ethanol concentration at 40°C for 60 min. Under these conditions, 65.2 ± 3.7 mg/g total flavonoid content was extracted from the roots, which were collected from salinized soil in late autumn of the third year. Antioxidant activity was evaluated through 1,1-diphenyl-2-picrylhydrazyl, More >

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