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  • Open Access

    ARTICLE

    Expression and Clinical Significance of ACTA2 in Osteosarcoma Tissue

    Lina Tang1,2, Haiyan Hu2, Yan Zhou2, Yujing Huang2, Yonggang Wang2, Yawen Zhang2, Jinrong Liang2, Zhenxin Wang1,*

    Oncologie, Vol.24, No.4, pp. 913-925, 2022, DOI:10.32604/oncologie.2022.026296 - 31 December 2022

    Abstract Objective: To investigate the expression of alpha–smooth muscle actin (ACTA2) in osteosarcoma tissues and its relationship with prognosis. Methods: Prognostic analysis of lung metastasis–related genes in osteosarcoma using the TCGA database. Single-cell sequencing detected the expression of ACTA2 in 11 osteosarcoma tissues. Paraf- fin-embedded tissues of 74 osteosarcoma patients treated at the Sixth People’s Hospital of Shanghai Jiao Tong University from 2014 to 2019 were collected, and tissue microarrays were prepared. ACTA2 expression was detected and scored by immunohistochemistry. According to the median value of the ACTA2 histochemical score, 74 patients were divided into two groups, the… More >

  • Open Access

    ARTICLE

    An Optimal Lempel Ziv Markov Based Microarray Image Compression Algorithm

    R. Sowmyalakshmi1,*, Mohamed Ibrahim Waly2, Mohamed Yacin Sikkandar2, T. Jayasankar1, Sayed Sayeed Ahmad3, Rashmi Rani3, Suresh Chavhan4,5

    CMC-Computers, Materials & Continua, Vol.69, No.2, pp. 2245-2260, 2021, DOI:10.32604/cmc.2021.018636 - 21 July 2021

    Abstract In the recent years, microarray technology gained attention for concurrent monitoring of numerous microarray images. It remains a major challenge to process, store and transmit such huge volumes of microarray images. So, image compression techniques are used in the reduction of number of bits so that it can be stored and the images can be shared easily. Various techniques have been proposed in the past with applications in different domains. The current research paper presents a novel image compression technique i.e., optimized Linde–Buzo–Gray (OLBG) with Lempel Ziv Markov Algorithm (LZMA) coding technique called OLBG-LZMA for… More >

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