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  • Open Access

    ARTICLE

    Dynamic Interaction Analysis of Coupled Axial-Torsional-Lateral Mechanical Vibrations in Rotary Drilling Systems

    Sabrina Meddah1,2,*, Sid Ahmed Tadjer3, Abdelhakim Idir4, Kong Fah Tee5,6,*, Mohamed Zinelabidine Doghmane1, Madjid Kidouche1

    Structural Durability & Health Monitoring, Vol.19, No.1, pp. 77-103, 2025, DOI:10.32604/sdhm.2024.053541 - 15 November 2024

    Abstract Maintaining the integrity and longevity of structures is essential in many industries, such as aerospace, nuclear, and petroleum. To achieve the cost-effectiveness of large-scale systems in petroleum drilling, a strong emphasis on structural durability and monitoring is required. This study focuses on the mechanical vibrations that occur in rotary drilling systems, which have a substantial impact on the structural integrity of drilling equipment. The study specifically investigates axial, torsional, and lateral vibrations, which might lead to negative consequences such as bit-bounce, chaotic whirling, and high-frequency stick-slip. These events not only hinder the efficiency of drilling… More >

  • Open Access

    ARTICLE

    Evaluating Public Sentiments during Uttarakhand Flood: An Artificial Intelligence Techniques

    Stephen Afrifa1,2,*, Vijayakumar Varadarajan3,4,5,*, Peter Appiahene2, Tao Zhang1, Richmond Afrifa6

    Computer Systems Science and Engineering, Vol.48, No.6, pp. 1625-1639, 2024, DOI:10.32604/csse.2024.055084 - 22 November 2024

    Abstract Users of social networks can readily express their thoughts on websites like Twitter (now X), Facebook, and Instagram. The volume of textual data flowing from users has greatly increased with the advent of social media in comparison to traditional media. For instance, using natural language processing (NLP) methods, social media can be leveraged to obtain crucial information on the present situation during disasters. In this work, tweets on the Uttarakhand flash flood are analyzed using a hybrid NLP model. This investigation employed sentiment analysis (SA) to determine the people’s expressed negative attitudes regarding the disaster. More >

  • Open Access

    ARTICLE

    Special Vehicle Target Detection and Tracking Based on Virtual Simulation Environment and YOLOv5-Block+DeepSort Algorithm

    Mingyuan Zhai1,2, Hanquan Zhang1, Le Wang1, Dong Xiao1,*, Zhengmin Gu3, Zhenni Li1

    CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 3241-3260, 2024, DOI:10.32604/cmc.2024.056241 - 18 November 2024

    Abstract In the process of dense vehicles traveling fast, there will be mutual occlusion between vehicles, which will lead to the problem of deterioration of the tracking effect of different vehicles, so this paper proposes a research method of virtual simulation video vehicle target tracking based on you only look once (YOLO)v5s and deep simple online and realtime tracking (DeepSort). Given that the DeepSort algorithm is currently the most effective tracking method, this paper merges the YOLOv5 algorithm with the DeepSort algorithm. Then it adds the efficient channel attention networks (ECA-Net) focusing mechanism at the back… More >

  • Open Access

    ARTICLE

    A Novel Filtering-Based Detection Method for Small Targets in Infrared Images

    Sanxia Shi, Yinglei Song*

    CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 2911-2934, 2024, DOI:10.32604/cmc.2024.055363 - 18 November 2024

    Abstract Infrared small target detection technology plays a pivotal role in critical military applications, including early warning systems and precision guidance for missiles and other defense mechanisms. Nevertheless, existing traditional methods face several significant challenges, including low background suppression ability, low detection rates, and high false alarm rates when identifying infrared small targets in complex environments. This paper proposes a novel infrared small target detection method based on a transformed Gaussian filter kernel and clustering approach. The method provides improved background suppression and detection accuracy compared to traditional techniques while maintaining simplicity and lower computational costs.… More >

  • Open Access

    ARTICLE

    Exploring the therapeutic potential of precision T-Cell Receptors (TCRs) in targeting KRAS G12D cancer through in vitro development

    WEITAO ZHENG1, DONG JIANG2, SONGEN CHEN1, MEILING WU1, BAOQI YAN2, JIAHUI ZHAI2, YUNQIANG SHI2, BIN XIE1, XINGWANG XIE2, KANGHONG HU1,*, WENXUE MA3,*

    Oncology Research, Vol.32, No.12, pp. 1837-1850, 2024, DOI:10.32604/or.2024.056565 - 13 November 2024

    Abstract Objectives: The Kirsten rat sarcoma virus (KRAS) G12D oncogenic mutation poses a significant challenge in treating solid tumors due to the lack of specific and effective therapeutic interventions. This study aims to explore innovative approaches in T cell receptor (TCR) engineering and characterization to target the KRAS G12D7-16 mutation, providing potential strategies for overcoming this therapeutic challenge. Methods: In this innovative study, we engineered and characterized two T cell receptors (TCRs), KDA11-01 and KDA11-02 with high affinity for the KRAS G12D7-16 mutation. These TCRs were isolated from tumor-infiltrating lymphocytes (TILs) derived from tumor tissues of patients More >

  • Open Access

    ARTICLE

    Liver-directed therapies for fibrolamellar carcinoma: A single-center experience

    SAM SON1, AKSHAAR BRAHMBHATT1, KEN ZHAO1, BRETT MARINELLI1, JAMES HARDING2, WILLIAM JARNAGIN3, GHASSAN K. ABOU-ALFA2, HOOMAN YARMOHAMMADI1,*

    Oncology Research, Vol.32, No.12, pp. 1831-1836, 2024, DOI:10.32604/or.2024.052985 - 13 November 2024

    Abstract Background: This article aims to present the single-institution outcomes of patients with Fibrolamellar Carcinoma (FLC) treated with liver-directed therapies (LDT). Methods: In this single-center retrospective study, all patients diagnosed with FLC who underwent LDT were identified. Between July 2012 and July 2023, six patients were identified. One patient was excluded due to bleeding. Demographic and clinical parameters were recorded. Complications within 30 days of the LDT were evaluated. Radiological treatment responses at 1, 6, and 12 months were assessed per mRECIST. Results: A total of five patients, which included three females and two males, were reviewed.… More >

  • Open Access

    COMMENTARY

    A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration

    A. NOEL GRAVINA1,2, NOELIA D´ELÍA1,2, LUCIANO A. BENEDINI2,3,*, PAULA MESSINA1,2

    BIOCELL, Vol.48, No.11, pp. 1517-1520, 2024, DOI:10.32604/biocell.2024.055513 - 07 November 2024

    Abstract This article navigates the relationship between biomaterials and osteogenic cell adhesion, highlighting the importance of mimicking the physiological response for bone tissue regeneration. Within this spirit is an initial description of the interaction between osteoblasts and osteoprogenitor cells with the extracellular matrix, explaining the leading role of integrins and cadherins in cell adhesion, and the intracellular signaling pathways elicited. Additionally, there is a focus on the strategies of advanced biomaterials that foster osteogenesis by replicating the native environment, taking advantage of these known specific signaling pathways. The final remarks lay on the need for careful More >

  • Open Access

    PROCEEDINGS

    Fragment Penetration Damage Characteristics of Typical Composite Armor

    Yuan Li1,3,*, Zhiqiang Fan1,2, Tao Suo1,3

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.3, pp. 1-2, 2024, DOI:10.32604/icces.2024.013336

    Abstract Light armored vehicles, as the primary means of force transport on contemporary battlefields, require not only high mobility but also better protection to meet the complex battlefield environment and mission requirements. Composite armor is widely used in the design of light armored vehicles due to its lightweight and excellent defensible performance. In this paper, the damage law of the composite armor of an infantry fighting vehicle, when penetrated by fragment-simulated projectiles (FSP), is studied by numerical simulation, and the homogeneous equivalent targets surrogating a combination of local protective armor and vulnerable parts are constructed based More >

  • Open Access

    PROCEEDINGS

    Thermal Insulating and Fire Retardant Si3N4 Nanowires Membranes Resistant to High-Temperatures up to 1300 °C

    Yeye Liu1, Leilei Zhang1,*, Ruonan Zhang1, Siqi Shao1, Lina Sun1, Xinyi Wan1, Tiantian Wang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012576

    Abstract Superior thermal insulating and fire-retardant ceramic membranes are urgently demanded in the aerospace, construction and chemical engineering industries. However, the generic characteristics of ceramic membranes, such as brittleness, structural collapse and crystallization-induced pulverization behavior, present a great plague to their practical applications. Herein, we report a highly flexible, mechanically stable, fire retardant and high-temperature-resistant ceramic membrane based on the interlocked Si3N4 nanowires formed by the precursor pyrolysis method. The Si3N4 nanowires membrane (SNM) has excellent high temperature resistance under alcohol lamp and butane spray lance. The thermal insulation with a thermal conductivity as low as 0.056… More >

  • Open Access

    PROCEEDINGS

    Dynamic Behaviors of a Moored Floating Production System in Actions of Internal Solitary Waves

    Junrong Wang1,2,*, Kuang He1, Botao Xie3, Chunlei He1, Wenbin Wu1,2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.011711

    Abstract Internal solitary waves (ISWs) a serious threat to moored floating structures in deep water, especially in South China Sea. On predicating dynamic response of a moored structure subjected to ISWs, previous researchers directly apply the pre-calculated ISW loading to the structure, which ignores the coupling effects between the structure and the ISW. To address this issue, this paper develops a coupled dynamic analysis model for moored structures, where the determination of ISW loading considers the effects of dynamic responses of floating structures. This model can simulate the action of various loading components on the floating… More >

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