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  • Open Access

    ARTICLE

    Drought Stress Alleviation in Chenopodium quinoa through Synergistic Effect of Silicon and Molybdenum via Triggering of SNF1-Associated Protein Kinase 2 Signaling Mechanism

    Asmat Askar1,#, Humaira Gul1,#, Mamoona Rauf1, Muhammad Arif2, Bokyung Lee3, Sajid Ali4,*, Abdulwahed Fahad Alrefaei5, Mikhlid H. Almutairi5, Zahid Ali Butt6, Ho-Youn Kim7, Muhammad Hamayun1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2455-2478, 2024, DOI:10.32604/phyton.2024.054508 - 30 September 2024

    Abstract Drought stress negatively impacts agricultural crop yields. By using mineral fertilizers and chemical regulators to encourage plant development and growth, its impact can be mitigated. The current study revealed that exogenous silicon (Si) (potassium silicate; K2Si2O5 at 1000 ppm) and molybdenum (Mo) (ammonium molybdate; (NH4)6Mo7O24•4H2O at 100 ppm) improved drought tolerance in quinoa (Chenopodium quinoa Willd). The research was conducted in a randomized complete block design with three biological replicates. The treatments comprised T0 (control, water spray), T4 (drought stress), and T1, T2, T3, T5, T6, and T7, i.e., foliar applications of silicon and molybdenum solutions individually… More >

  • Open Access

    ARTICLE

    Targeted anti-tumor synergistic effects of Myc decoy oligodeoxynucleotides-loaded selenium nanostructure combined with chemoradiotherapy on LNCaP prostate cancer cells

    ROGHAYEH GHORBANI1, MAHMOUD GHARBAVI2, ALI SHARAFI3,4, ELHAM RISMANI5, HAMED REZAEEJAM6, YOUSEF MORTAZAVI1,*, BEHROOZ JOHARI3,*

    Oncology Research, Vol.32, No.1, pp. 101-125, 2024, DOI:10.32604/or.2023.044741 - 15 November 2023

    Abstract In the present study, we investigated the synergistic effects of targeted methotrexate-selenium nanostructure containing Myc decoy oligodeoxynucleotides along with X-irradiation exposure as a combination therapy on LNCaP prostate cancer cells. Myc decoy ODNs were designed based on the promoter of Bcl-2 gene and analyzed by molecular docking and molecular dynamics assays. ODNs were loaded on the synthesized Se@BSA@Chi-MTX nanostructure. The physicochemical characteristics of nanostructures were determined by FTIR, DLS, UV-vis, TEM, EDX, in vitro release, and hemolysis tests. Subsequently, the cytotoxicity properties of them with and without X-irradiation were investigated by uptake, MTT, cell cycle, apoptosis, and… More > Graphic Abstract

    Targeted anti-tumor synergistic effects of Myc decoy oligodeoxynucleotides-loaded selenium nanostructure combined with chemoradiotherapy on LNCaP prostate cancer cells

  • Open Access

    ARTICLE

    The Application of Fertilizer and AMF Promotes Growth and Reduces the Cadmium and Lead Contents of Ryegrass (Lolium multiflorum L.) in a Copper Mining Area

    Jiaxin Chen1,#, Jiawei Guo1,#, Zhixin Yang1, Jiqing Yang2,*, Hengwen Dong3, Huiyun Wang3, Yalei Wang3, Fangdong Zhan1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.2, pp. 471-485, 2023, DOI:10.32604/phyton.2022.023660 - 12 October 2022

    Abstract Heavy metal-polluted soil was collected from the Pulang copper mine in Shangri-La City, Yunnan Province, Southwest China. The effects of fertilizer (organic and inorganic) and arbuscular mycorrhizal fungi (AMF) on ryegrass (Lolium multiflorum L.) growth, root morphology, mineral nutrition and cadmium (Cd) and lead (Pb) contents were investigated by pot experiments. The results showed that both fertilizer and AMF significantly ameliorated the root morphology and mineral nutrition, reduced the Cd and Pb contents, and promoted the growth of ryegrass. Among all treatments, the combined application of organic–inorganic compound fertilizer with AMF had the highest effect, resulting… More >

  • Open Access

    ARTICLE

    The synergistic effects of PRDX5 and Nrf2 on lung cancer progression and drug resistance under oxidative stress in the zebrafish models

    SITONG QIAN1,2,#, YING FANG1,#, CHENGYUN YAO1,#, YONGSHENG WANG3,#, ZHI ZHANG1, XIAOHUA WANG1, JIN GAO1, YONG FENG1, LEI SUN1, RUNYUE ZOU2, GUOREN ZHOU1,*, JINJUN YE1,*, RUIXUE XIA4,*, HONGPING XIA5,6,*

    Oncology Research, Vol.30, No.2, pp. 53-64, 2022, DOI:10.32604/or.2022.026302 - 05 January 2023

    Abstract Previous studies have shown that PRDX5 and Nrf2 are antioxidant proteins related to abnormal reactive oxidative species (ROS). PRDX5 and Nrf2 play a critical role in the progression of inflammations and tumors. The combination of PRDX5 and Nrf2 was examined by Co-immunoprecipitation, western blotting and Immunohistochemistry. H2O2 was applied to affect the production of ROS and induced multi-resistant protein 1 (MRP1) expression in NSCLC cells. The zebrafish models mainly investigated the synergistic effects of PRDX5 and Nrf2 on lung cancer drug resistance under oxidative stress. We showed that PRDX5 and Nrf2 form a complex and significantly More >

  • Open Access

    ARTICLE

    Influence of Beta-Cyclodextrin Functionalized Tin Phenylphosphonate on the Thermal Stability and Flame Retardancy of Epoxy Composites

    Yongming Chen1,2,#, Shuai Huang1,#, Han Zhao1, Ru Yang2, Yining He1, Tianyu Zhao1, Yunlong Zhang1, Qinghong Kong1,*, Shasha Sun3,*, Junhao Zhang3

    Journal of Renewable Materials, Vol.10, No.12, pp. 3119-3130, 2022, DOI:10.32604/jrm.2022.019576 - 14 July 2022

    Abstract To enhance the thermal stability and flame retardancy of epoxy resin (EP), beta-cyclodextrin (β-CD) is successfully introduced into the layered tin phenylphosphonate (SnPP), which is incorporated into EP matrix for preparing EP/β-CD@SnPP composites. The results indicate that the addition of β-CD@SnPP obviously improve the thermal stability and residual yield of EP composites at higher temperature. When the amount of β-CD@SnPP is only 4 wt%, EP/4β-CD@SnPP composites pass V-1 rating, and LOI value is up to 30.8%. Meanwhile, β- CD@SnPP effectively suppress the heat release and reduce the smoke production of EP/β-CD@SnPP composites in combustion, and More >

  • Open Access

    ARTICLE

    Effect of MMT on Flame Retardancy of PLA/IFR/LDH Composites

    Ping Zhang, Siyu Gan, Lin Chen*, Hao Chen, Chunhui Jia, Yingke Fu, Ying Xiong*

    Journal of Renewable Materials, Vol.10, No.11, pp. 2937-2947, 2022, DOI:10.32604/jrm.2022.019590 - 29 June 2022

    Abstract Nano filler synergistic intumescent flame retardant (IFR) system is an effective way to improve the flame retardant properties of polymer. In this study, the effects of montmorillonite (MMT) on the flame retardant properties of polylactic acid/layered double hydroxides (PLA/LDH) and PLA/IFR/LDH were investigated. The results show that both LDH and LDH/IFR can reduce the peak heat release rate (HRR) of PLA and prolong the combustion time of PLA; When a proportionate MMT is introduced into PLA/LDH and PLA/IFR/LDH systems, respectively, MMT will not only affect the degradation process of PLA composites during combustion, but also More >

  • Open Access

    ARTICLE

    Development of Steel Slag-Based Solidification/Stabilization Materials for High Moisture Content Soil

    Yu Jia1, Sudong Hua1,*, Liying Qian2, Xiaojian Ren2, Jie Zuo3, Yanfang Zhang3

    Journal of Renewable Materials, Vol.10, No.3, pp. 735-749, 2022, DOI:10.32604/jrm.2022.016819 - 28 September 2021

    Abstract To solve the problems of high moisture content, high viscosity, and poor engineering mechanical properties of soil, this paper using with steel slag (SS) and desulfurization ash (DS) as initial raw materials, realizing the cooperative treatment of solid waste and solidification of silt soil. The synergistic utilization of SS and DS can reduce the production cost of curing agent and promote its own consumption. According to blended cement of various SS contents and inspected compressive strength performances, the most suitable raw materials ratio was selected. The best formula for this curing agent is cement:steel slag = 3:7… More >

  • Open Access

    ARTICLE

    EXPERIMENTAL INVESTIGATION ON DRAG REDUCTION OF MIXED PEO AND CTAC/NASAL AQUEOUS SOLUTION IN A ROTATING DISK APPARATUS

    Wei Tiana , Mingjun Panga,*, Na Xub,†

    Frontiers in Heat and Mass Transfer, Vol.16, pp. 1-12, 2021, DOI:10.5098/hmt.16.13

    Abstract Drag reduction (DR) by the additive of mixed surfactant and polymer is investigated in detail in a rotating disk apparatus (RDA). Polyethylene oxide (PEO) and Cetyltrimethyl ammonium chloride (CTAC)/sodium salicylate (NaSal) are chosen as polymer and surfactant, respectively. It is investigated on the influence of combination concentration of polymer & surfactant, temperature and Reynolds number on the drag-reducing rate. The present experimental results show that the drag-reducing rate of the mixed solution is definitely higher than that of the pure PEO or CTAC/NaSal solutions. This phenomenon is especially sharp at the high temperature and/or the… More >

  • Open Access

    ARTICLE

    Synergistic Effect of Nano-α-Al2O3 Particles on Mechanical Properties of Glass-fibre reinforced Epoxy Hybrid Composites

    ANIL KUMAR VEERAPANENI1, CHANDRASEKAR KUPPAN2,*, MURTHY CHAVALI3,*

    Journal of Polymer Materials, Vol.37, No.3-4, pp. 121-130, 2020, DOI:10.32381/JPM.2020.37.3-4.1

    Abstract The mechanical properties of hybrid nanocomposites made of epoxy/glass fibre dispersed with nano-α-Al2 O3 powder at different weight percentages were studied.The effect of nano-α- Al2O3 size and wt% on mechanical properties like tensile, flexural, interlaminar shear stress and hardness enhanced because of their higher surface area and interfacial polymer-metal interaction. The nanoparticle embedded laminates have shown improvement in flexural strength,and hardness when compared to laminate without nano-α-Al2 O3. The properties varied with the loading and size of the nanoparticles. The tensile strength was highest for 0.5 wt% of 200nm nano-α-Al2O3, which is 167.80 N/m2.The highest flexural strength was observed More >

  • Open Access

    ARTICLE

    Synergistic Effect of Halloyosite Nanotube and Nanocellulose on Thermal and Mechanical Properties of Poly (Ethylmethacrylate-co-Acrylonitrile) Bionanocomposites

    Karima Ben Hamou1,2,*, Amal Kadimi1, Remo Merijs Meri3, Sergei Gaidukov3, Hamid Kaddami1, Mustapha Raihane1, Mouhamed Lahcini1, Fouad Erchiqui2

    Journal of Renewable Materials, Vol.8, No.3, pp. 301-317, 2020, DOI:10.32604/jrm.2020.08141 - 01 March 2020

    Abstract This work reports a comprehensive study on poly (Ethylmethacrylateco-Acrylonitrile) Poly(EMA-AN) nanocomposites reinforced with a hybrid mixture of nanoreiforcements based on nanocrystals of cellulose (NCC) (1 or 5% wt) and halloysite nanotubes (HNTs) (1 or 5% wt). The morphology, thermal and mechanical properties of these nanocomposites were characterized. Homogeneous dispersion of the nanofillers has been shown by scanning electron microscopy. A significant increase of the rubbery modulus and glass transition temperature were obtained upon filler addition, due to the reduction of mobility of the matrix macromolecular chains. On the other hand, compared with the neat Poly(EMAAN), More >

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