Hiroki Nagamine¹, Masaru Miura^1,*, Jun Maeda¹, Takumi Nishiki¹, Maasa Sato², Fumie Takechi³, Shigeru Tateno⁴, Tomoko Ishizu⁵, Yumi Shiina⁶, Ken Kato⁷, Hiroshi Ono⁸, Hiroyuki Yamagishi⁹, Koichiro Niwa⁶

Congenital Heart Disease, Vol.19, No.4, pp. 351-362, 2024, DOI:10.32604/chd.2024.051837 - 31 October 2024

Abstract Background: Aortic root dilatation occurs in adults with tetralogy of Fallot (TOF) after surgical repair, but the longitudinal changes are unclear. The main research aim is to determine the annual dilatation rate of aorta in adults with repaired TOF. Methods: The present, multicentric, prospective cohort study assessed the rate of aortic diameter change in adults aged 20 years or older with TOF, including pulmonary artery atresia, who underwent surgical repair. Clinical data, focusing on echocardiograms, were collected at three-year intervals from seven hospitals. Results: In total, 104 patients (58 males; median age: 29 years) were enrolled.… More > Graphic Abstract

Jiawang Xiao, Jianming Wang, Zhongchao Wang, Lili Meng, Ming Zhao, Qiguang Wang^*

Congenital Heart Disease, Vol.19, No.3, pp. 293-303, 2024, DOI:10.32604/chd.2024.051427 - 26 July 2024

Abstract Background: Transcatheter closure (TCC) has emerged as the preferred treatment for selected congenital heart disease (CHD). While TCC offers benefits for patients with postoperative residual shunts, understanding its mid- and long-term efficacy and safety remains crucial. Objective: This study aims to assess the mid- and long-term safety and efficacy of TCC for patients with residual atrial or ventricular septal shunts following CHD correction. Methods: In this consecutive retrospective study, we enrolled 35 patients with residual shunt who underwent TCC or surgical repair of CHD between June 2011 to October 2022. TCC candidacy was determined based on… More >

Jae Hong Lee¹, Sungkyu Cho^2,*, Jae Gun Kwak², Hye Won Kwon², Woong-Han Kim², Mi Kyoung Song³, Sang-Yun Lee³, Gi Beom Kim³, Eun Jung Bae³

Congenital Heart Disease, Vol.19, No.1, pp. 69-83, 2024, DOI:10.32604/chd.2024.045137 - 20 March 2024

Abstract Background: The optimal surgical timing and clinical outcomes of ventricular septal defect (VSD) closure in neonates remain unclear. We aimed to evaluate the clinical outcomes of VSD closure in neonates (age ≤ 30 days). Methods: We retrospectively reviewed 50 consecutive neonates who underwent VSD closure for isolated VSDs between August 2003 and June 2021. Indications for the procedure included congestive heart failure/failure to thrive and pulmonary hypertension. Major adverse events (MAEs) were defined as the composite of all-cause mortality, reoperation, persistent atrioventricular block, and significant (≥grade 2) valvular dysfunction. Results: The median age and body weight… More >

Pietro Paolo Tamborrino^1,2, Corrado Di Mambro^1,2,*, Cecilia Marcolin^1,2, Walter Vignaroli³, Giulia Cafiero⁴, Gianluca Brancaccio³, Sonia Albanese³, Massimo Stefano Silvetti^1,2, Adriano Carotti³, Fabrizio Drago^1,2

Congenital Heart Disease, Vol.16, No.1, pp. 85-94, 2021, DOI:10.32604/CHD.2021.013038 - 23 December 2020

Abstract Introduction: While previous studies only focused on the arrhythmic risk associated with specific correction strategies, this study evaluates this risk in a large cohort of paediatric patients with all phenotypes of PA-IVS after surgical repair. Methods: In this single centre observational cohort study, we retrospectively evaluated 165 patients with a diagnosis of PA-IVS and we excluded those with an exclusively percutaneous treatment, patients lost or with insufficient follow-up and those affected by other arrhythmic syndromes. Surgical history and clinical outcomes were reviewed. Results: 86 patients were included in the study (54 male [62.8%], mean age 16.4 ±… More >

An Van Berendoncks^1,2, Roderick Van Grootel¹, Jackie McGhie¹, Matthijs van Kranenburg¹, Myrthe Menting¹, Judith A.A.E. Cuypers¹, Ad J.J.C. Bogers³, Maarten Witsenburg¹, Jolien W. Roos‐Hesselink¹, Annemien E. van den Bosch¹

Congenital Heart Disease, Vol.14, No.4, pp. 628-637, 2019, DOI:10.1111/chd.12762

Abstract Aims: Reliable evaluation of the severity and consequences of pulmonary regurgita‐ tion (PR) in patients with repaired tetralogy of Fallot (TOF) is crucial to timely identify the need for pulmonary valve intervention. We aimed to identify the accuracy of echocardiographic parameters to differentiate between moderate and severe PR, using phase contrast cardiac magnetic resonance imaging (CMR) as gold standard.
Methods and results: In this cross‐sectional study, 45 TOF patients with both echo‐ cardiographic and CMR measurements of PR were enrolled. All quantitative and semiquantitative echocardiographic measurements such as pressure half time (PHT), Color flow jet width (CFJW),… More >

Christine M. Riley¹, Christopher W. Mastropietro², Peter Sassalos³, Jason R. Buckley⁴, John M. Costello⁴, Ilias Iliopoulos⁵, Aimee Jennings⁶, Katherine Cashen⁷, Sukumar Suguna Narasimhulu⁸, Keshava M. N. Gowda⁹, Arthur J. Smerling¹⁰, Michael Wilhelm¹¹, Aditya Badheka¹², Adnan Bakar^13,14, Elizabeth A. S. Moser¹⁵, Venu Amula¹⁶

Congenital Heart Disease, Vol.14, No.6, pp. 1078-1086, 2019, DOI:10.1111/chd.12849

Abstract Background: Elevated pulmonary vascular resistance (PVR) is common following repair of truncus arteriosus. Inhaled nitric oxide (iNO) is an effective yet costly therapy that is frequently implemented postoperatively to manage elevated PVR.
Objectives: We aimed to describe practice patterns of iNO use in a multicenter cohort of patients who underwent repair of truncus arteriosus, a lesion in which recovery is often complicated by elevated PVR. We also sought to identify patient and center factors that were more commonly associated with the use of iNO in the postoperative period.
Design: Retrospective cohort study.
Setting: 15 tertiary care pediatric referral centers.
Patients:… More >