Hua Tao, Yiqin Zhou, Chengyun Yao, Dayong Gu, Wei Chen, Jincheng Lu

Oncology Research, Vol.25, No.8, pp. 1357-1362, 2017, DOI:10.3727/096504017X14889842609577

Abstract The aim of this study was to evaluate the efficacy and toxicity of intensity-modulated radiotherapy concurrent with weekly docetaxel in patients with node-positive esophageal squamous cell carcinoma after radical surgery. Between January 2011 and December 2013, a total of 46 eligible patients were enrolled. All patients received intensity-modulated radiotherapy concurrent with weekly docetaxel (20 mg/m² ). Patients were treated 5 days per week at 2.0 Gy/day. The total dose of external radiotherapy given was 50 Gy in 25 fractions. The primary endpoints included treatment completion and safety. The secondary endpoint was to assess whether the approach… More >

Gustavo Cruz^1,*, Santiago Pedroza², Juan F. Vélez³, Jessica Largo², Juan F. Tejada⁴, Jorge H. Mejía-Mantilla⁵

Congenital Heart Disease, Vol.19, No.2, pp. 207-218, 2024, DOI:10.32604/chd.2024.044244

Abstract Background: Failure to rescue has been an effective quality metric in congenital heart surgery. Conversely, morbidity and mortality depend greatly on non-modifiable individual factors and have a weak correlation with better-quality performance. We aim to measure the complications, mortality, and risk factors in pediatric patients undergoing congenital heart surgery in a high-complexity institution located in a middle-income country and compare it with other institutions that have conducted a similar study. Methods: A retrospective observational study was conducted in a high-complexity service provider institution, in Cali, Colombia. All pediatric patients undergoing any congenital heart surgery between… More >

Jae Hong Lee¹, Sungkyu Cho^2,*, Jae Gun Kwak², Hye Won Kwon², Woong-Han Kim², Mi Kyoung Song³, Sang-Yun Lee³, Gi Beom Kim³, Eun Jung Bae³

Congenital Heart Disease, Vol.19, No.1, pp. 69-83, 2024, DOI:10.32604/chd.2024.045137

Abstract Background: The optimal surgical timing and clinical outcomes of ventricular septal defect (VSD) closure in neonates remain unclear. We aimed to evaluate the clinical outcomes of VSD closure in neonates (age ≤ 30 days). Methods: We retrospectively reviewed 50 consecutive neonates who underwent VSD closure for isolated VSDs between August 2003 and June 2021. Indications for the procedure included congestive heart failure/failure to thrive and pulmonary hypertension. Major adverse events (MAEs) were defined as the composite of all-cause mortality, reoperation, persistent atrioventricular block, and significant (≥grade 2) valvular dysfunction. Results: The median age and body weight… More >

Arunn Narasimhan^*, Kaushal Kumar Jha

Frontiers in Heat and Mass Transfer, Vol.2, No.3, pp. 1-8, 2011, DOI:10.5098/hmt.v2.3.3005

Abstract Pan Retinal photocoagulation (PRP), a retinal laser surgical process, is simulated using a three-dimensional bio-heat transfer numerical model. Spots of two different type of array, square array of 3 × 3 spots and a circular array of six spots surrounding a central spot, are sequentially irradiated. Pennes bio-heat transfer model is used as the governing equation. Finite volume method is applied to find the temperature distribution due to laser irradiation inside the human eye. Each spot is heated for 100 ms and subsequently cooled for 100 ms with an initial laser power of 0.2 W. More >

Vitaliy Suvorov^1,2,*, Olga Loboda², Maria Balakina¹, Igor Kulczycki²

Congenital Heart Disease, Vol.18, No.5, pp. 491-505, 2023, DOI:10.32604/chd.2023.030583

Abstract Background: Three-dimensional printing technology may become a key factor in transforming clinical practice and in significant improvement of treatment outcomes. The introduction of this technique into pediatric cardiac surgery will allow us to study features of the anatomy and spatial relations of a defect and to simulate the optimal surgical repair on a printed model in every individual case. Methods: We performed the prospective cohort study which included 29 children with congenital heart defects. The hearts and the great vessels were modeled and printed out. Measurements of the same cardiac areas were taken in the… More > Graphic Abstract

Dongyun Bie^1,#, Hongbai Wang^1,#, Chaobin Zhang², Chunrong Wang³, Yuan Jia¹, Su Yuan¹, Sheng Shi¹, Jiangshan Huang¹, Jianhui Wang^1,*, Fuxia Yan^1,*

Congenital Heart Disease, Vol.18, No.4, pp. 475-488, 2023, DOI:10.32604/chd.2023.028017

Abstract Purpose: This study sought to explore the effect of intraoperative mean blood glucose levels and variability on postoperative acute kidney injury (AKI) in children undergoing congenital cardiac surgery. Methods: We conducted a prospective nested case-control study in children (age < 18 years) undergoing congenital heart surgery with cardiopulmonary bypass (CPB) at the Fuwai Hospital between April 01, 2022 and July 30, 2022. Cases were individuals who developed AKI within the first postoperative 7 days (AKI group) and controls were those without AKI (Non-AKI group) according to KDIGO criteria. AKI and Non-AKI groups unmatched and 1:1 matched by… More > Graphic Abstract

Birgitta Svensson^1,2,*, Petru Liuba^1,2, Anne Wennick³, Malin Berghammer^4,5

Congenital Heart Disease, Vol.18, No.3, pp. 349-359, 2023, DOI:10.32604/chd.2023.028391

Abstract Background: Parents of children with complex right ventricular outflow tract (RVOT) anomalies are confronted with their child’s need for heart surgery early in life and repeated reoperations later on. Preoperative assessment needs to be performed whenever an indication for reoperation is suspected. The aim was to illuminate the experiences of parents of children diagnosed with RVOT anomalies, in particular, how they experience their child’s heart disease and everyday life during the assessment and after the decision on whether to perform a reoperation. Method: Individual interviews (n = 27) were conducted with nine parents on three occasions between… More >

Jae Gun Kwak¹, Eung Re Kim², Taeyoung Yun¹, Sungkyu Cho¹, Chang-Ha Lee², Woong-Han Kim^1,*

Congenital Heart Disease, Vol.18, No.3, pp. 325-336, 2023, DOI:10.32604/chd.2023.027758

Abstract Objectives: To access the effectiveness of our modified right-ventricular overhauling procedure on tricuspid valve (TV) growth in patients with pulmonary atresia with intact ventricular septum (PAIVS). Methods: We retrospectively reviewed 21 patients with PAIVS who underwent modified right ventricular overhauling (mRVoh) between 2008 and 2019 at two institutions. Our mRVoh consisted of wide resection of hypertrophied infundibular and trabecular muscle, peeling off fibrotic endocardial tissue in the right ventricle (RV) cavity, surgical pulmonary valvotomy, and Blalock-Taussig shunt or banding of ductus arteriosus under cardiopulmonary bypass. The TV annulus sizes were measured and analyzed using echocardiography… More > Graphic Abstract

Rohan Suresh Daniel^1,2, Georgia K. Schmidt^1,2, Hayato Nakanishi^1,2, Karen Smayra^1,2, Mariah N. Mascara^1,2, Dilip K. Vankayalapati^1,2, Reem H. Matar^1,2,3, Christian A. Than^1,2,4, George Shiakos⁵, Ioannis Tzanavaros^2,5,*

Congenital Heart Disease, Vol.18, No.2, pp. 245-265, 2023, DOI:10.32604/chd.2023.027596

Abstract Background: Persistent patent ductus arteriosus (pPDA) is a common condition in preterm infants. This meta-analysis aimed to assess the safety and efficacy of transcatheter closure (TC) when compared to surgical ligation (SL) in preterm infants with pPDA. Methods: A literature search of Ovid Cochrane Library, Medline, Embase, Epub, Scopus, PMC Preprints, and was conducted from inception to May 06, 2022. Eligible studies reported infants diagnosed with pPDA born at ≤2000 g birth weight or at ≤37 weeks’ who underwent TC or SL as treatment. This review was registered in PROSPERO (CRD42022325944). Results: From 97 studies screened, 8… More >

Alain J. Poncelet^1,*, Maureen Peers de Nieuwburgh², Stéphane Moniotte², Geoffroy de Beco¹, Karlien Carbonez², Jean E. Rubay¹, Thierry Detaille³, Laurent Houtekie³, Mona Momeni⁴

Congenital Heart Disease, Vol.18, No.2, pp. 151-168, 2023, DOI:10.32604/chd.2023.022636

Abstract Background: Most outcome studies in congenital cardiac surgery for “low weight” neonates include patients undergoing surgery without cardiopulmonary bypass (CPB). The primary objective of our study was to identify risk factors for in-hospital mortality in neonates weighing less than 3 Kg and undergoing surgery with CPB. In addition, we compared the effect of early surgery with CPB (before 37W-gestational age (GA)) for congenital heart disease to delayed surgery until a corrected GA of 37 weeks in an attempt to promote weight gain. Methods: Retrospective single-center study including all patients operated between 1997 and 2017. Uni- and… More >