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  • Open Access

    PROCEEDINGS

    A Multiscale Dynamic Model of Cell–Substrate Interfaces

    Huiyan Liang1, Wei Fang1, Xiqiao Feng1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012719

    Abstract Cell–extracellular matrix (ECM) interactions play a pivotal role in many functions of cells, for example, sensing, signaling, migration, and gene expression. The spatial-temporal dynamic evolution of cell–substrate adhesions involves complicated mechano-bio-chemical coupling mechanisms of integrin, adaptor and signaling proteins, and the interplay between the cytoskeleton and ECM as well. In this paper, we establish a multiscale dynamic model of cell–substrate interfaces considering intermolecular force transmission pathways, i.e., intra- and extra-cellular bond dynamics, and mechanochemical coupling regulations. To illustrate its applications, this model is used to reproduce several adhesion-related experimental phenomena of cells, including substrate rigidity… More >

  • Open Access

    ARTICLE

    The Disintegration of a Floating Ferrofluid Layer into an Ordered Drop System in a Vertical Magnetic Field

    Christina Khokhryakova1,*, Konstantin Kostarev2, Irina Mizeva3

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.10, pp. 2205-2218, 2024, DOI:10.32604/fdmp.2024.051053 - 23 September 2024

    Abstract Magnetic fluids, also known as ferrofluids, are versatile functional materials with a wide range of applications. These applications span from industrial uses such as vacuum seals, actuators, and acoustic devices to medical uses, including serving as contrast agents for magnetic resonance imaging (MRI), delivering medications to specific locations within the body, and magnetic hyperthermia for cancer treatment. The use of a non-wettable immiscible liquid substrate to support a layer of magnetic fluid opens up new possibilities for studying various fluid flows and related instabilities in multi-phase systems with both a free surface and an interface.… More > Graphic Abstract

    The Disintegration of a Floating Ferrofluid Layer into an Ordered Drop System in a Vertical Magnetic Field

  • Open Access

    ARTICLE

    Film Flow of Nano-Micropolar Fluid with Dissipation Effect

    Abuzar Abid Siddiqui1, Mustafa Turkyilmazoglu2,3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2487-2512, 2024, DOI:10.32604/cmes.2024.050525 - 08 July 2024

    Abstract The physical problem of the thin film flow of a micropolar fluid over a dynamic and inclined substrate under the influence of gravitational and thermal forces in the presence of nanoparticles is formulated. Five different types of nanoparticle samples are accounted for in this current study, namely gold Au, silver Ag, molybdenum disulfide MoS2, aluminum oxide Al2O3, and silicon dioxide SiO2. Blood, a micropolar fluid, serves as the common base fluid. An exact closed-form solution for this problem is derived for the first time in the literature. The results are particularly validated against those for the Newtonian fluid… More >

  • Open Access

    ARTICLE

    Developing a Breast Cancer Resistance Protein Substrate Prediction System Using Deep Features and LDA

    Mehdi Hassan1,2, Safdar Ali3, Jin Young Kim2,*, Muhammad Sanaullah4, Hani Alquhayz5, Khushbakht Safdar6

    CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 1643-1663, 2023, DOI:10.32604/cmc.2023.038578 - 30 August 2023

    Abstract Breast cancer resistance protein (BCRP) is an important resistance protein that significantly impacts anticancer drug discovery, treatment, and rehabilitation. Early identification of BCRP substrates is quite a challenging task. This study aims to predict early substrate structure, which can help to optimize anticancer drug development and clinical diagnosis. For this study, a novel intelligent approach-based methodology is developed by modifying the ResNet101 model using transfer learning (TL) for automatic deep feature (DF) extraction followed by classification with linear discriminant analysis algorithm (TLRNDF-LDA). This study utilized structural fingerprints, which are exploited by DF contrary to conventional More >

  • Open Access

    ARTICLE

    Substrate, Hormone, Winnowing, and Stratification Influence the Seed Germination of Ilex asprella (Hook. et Arn.) Champ. ex Benth

    Yuquan Huang1,2, Fan Wei1, Qing Ma2, Yang Lin1, Jinpeng Huang2, Yanxia Zhu1,*, Danfeng Tang1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 2105-2116, 2023, DOI:10.32604/phyton.2023.029205 - 29 May 2023

    Abstract Ilex asprella (Hook. et Arn.) Champ. ex Benth is one of the most important traditional Chinese medicines in southern China. The seeds of Ilex asprella usually have extremely low germination due to their dormancy characteristics, which severely impacts the efficiency of seedling raising and increases labor costs. In this study, to improve the seed germination of I. asprella, the effects of germination substrate, hormone, winnowing, and stratification treatments on the seed germination of I. asprella were investigated. The results of the germination matrix showed that the highest germination percentage of 45.2% was achieved under the 20°C/10°C day/night temperature and… More >

  • Open Access

    ARTICLE

    Molecular Dynamics Simulation of Interface Properties between Water-Based Inorganic Zinc Silicate Coating Modified by Organosilicone and Iron Substrate

    Hengjiao Gao1, Yuqing Xiong1,*, Kaifeng Zhang1, Shengzhu Cao1, Mingtai Hu1, Yi Li1, Ping Zhang2, Xiaoli Liu3

    Journal of Renewable Materials, Vol.11, No.4, pp. 1715-1729, 2023, DOI:10.32604/jrm.2022.024023 - 01 December 2022

    Abstract The interface properties of Fe(101)/zinc silicate modified by organo-siloxane (KH-570) was studied by using the method of molecular dynamics simulation. By calculating the temperature and energy fluctuation of equilibrium state, equilibrium concentration distribution, MSD of layer and different groups, and interaction energy of two interface models, the influencing mechanism on the interface properties of adding organosiloxane into coating system was studied at the atomic scale. It shows that the temperature and energy of interface oscillated in a small range and it was exited in a state of dynamic equilibrium within the initial simulation stage (t More > Graphic Abstract

    Molecular Dynamics Simulation of Interface Properties between Water-Based Inorganic Zinc Silicate Coating Modified by Organosilicone and Iron Substrate

  • Open Access

    ARTICLE

    A Substrate Integrated Waveguide Based Filtenna for X and Ku Band Application

    S. Leo Pauline1,*, T. R. GaneshBabu2

    Intelligent Automation & Soft Computing, Vol.35, No.1, pp. 465-473, 2023, DOI:10.32604/iasc.2023.024030 - 06 June 2022

    Abstract In this paper Substrate Integrated Waveguide-based filtenna operating at Ku band is proposed. The model is designed on a low loss dielectric substrate having a thickness of 0.508 mm and comprises of shorting vias along two edges of the substrate walls. To realize a bandpass filter, secondary shorting vias are placed close to primary shorting vias. The dimension and position of the vias are carefully analyzed for Ku band frequencies. The model is fabricated on Roger RT/duroid 5880 and the performance characteristics are measured. The proposed model achieves significant impedance characteristics with wider bandwidth in the More >

  • Open Access

    ARTICLE

    STUDY OF SUBSTRATE CONDUCTANCE EFFECT ON THE COOLING OF ELECTRONIC COMPONENTS

    Shankar Durgam

    Frontiers in Heat and Mass Transfer, Vol.18, pp. 1-10, 2022, DOI:10.5098/hmt.18.49

    Abstract This article explores experimentally and numerically the effect of conductance on cooling of electronic chips by forced air flow in a vertical channel for thermal control. Experiments are conducted using substrates of FR4, bakelite, copper clad board (single layer) equipped with aluminum heat sources at uniform heat fluxes of 1000, 2000, and 3000 W/m2 at 500 ≤ Re ≤ 1500. Computer simulations are performed to validate experimental results using a finite element method based COMSOL Multiphysics 4.3b software and the results are in agreements of below 10%. The temperatures obtained showed high thermal conductance copper clad More >

  • Open Access

    ARTICLE

    Effects of Drought Stress on Key Enzymes of Carbon Metabolism, Photosynthetic Characteristics and Agronomic Traits of Soybean at the Flowering Stage under Different Soil Substrates

    Shuang Song1, Xiaomei Li2, Xin Wang1, Qi Zhou1, Yongping Li1, Xiaojing Wang1, Shoukun Dong1,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.11, pp. 2475-2490, 2022, DOI:10.32604/phyton.2022.021090 - 12 July 2022

    Abstract Soybean is an important legume food crop, and its seeds are rich in nutrients, providing humans and animals with edible oil and protein feed. However, soybean is sensitive to water requirements, and drought is an important factor limiting soybean yield and quality. This study used Heinong 84 (drought resistant variety) and Hefeng 46 (intermediate variety) as tested varieties planted in chernozem, albic, and black soils. The effects of drought stress on the activities of key enzymes in carbon metabolism and photosynthetic characteristics of soybean were studied during the flowering stage, most sensitive to water. (1)… More >

  • Open Access

    ARTICLE

    Short-Term and Long-Term Effects of Natural and Artificial Carbonaceous Substrates on Greenhouse Gas Fluxes

    Jürgen Kern1,*, Judy Libra1, Christian Ammon1, York Neubauer2, Wenceslau Teixeira3

    Journal of Renewable Materials, Vol.10, No.7, pp. 1773-1786, 2022, DOI:10.32604/jrm.2022.019608 - 07 March 2022

    Abstract The emissions of two greenhouse gases (GHG), carbon dioxide (CO2) and nitrous oxide (N2O), from six substrates with different carbonaceous content were compared in short and long-term incubation experiments. Three natural soils and three artificial chars were mixed with carbon (C) poor soil (Cambisol) to simulate real conditions after application of char to farmland. The natural soils were a Cambisol, an Anthrosol and a Histosol with C contents of 1.3%, 4.4% and 13.2%, respectively. The three chars produced through thermal conversion of wood chips by hydrothermal carbonisation (HTC), fluidized bed gasification and pyrolysis had C… More >

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