S. Praveenkumar^*, T. Karthick

Computer Systems Science and Engineering, Vol.48, No.4, pp. 1073-1073, 2024, DOI:10.32604/csse.2024.054414

Abstract This article has no abstract. More >

Heng Zhang^1,2, Chao Su^2,*, Xiaohu Chen¹, Zhizhong Song¹, Weijie Zhan³

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2977-3000, 2024, DOI:10.32604/cmes.2024.047972

Abstract Temperature-induced cracking during the construction of mass concrete is a significant concern. Numerical simulations of concrete temperature have primarily assumed that the concrete is placed in an open environment. The problem of heat transfer between the air and concrete has been simplified to the concrete’s heat dissipation boundary. However, in the case of tubular concrete structures, where air inlet and outlet are relatively limited, the internal air temperature does not dissipate promptly to the external environment as it rises. To accurately simulate the temperature and creep stress in tubular concrete structures with enclosed air spaces… More >

SIYUAN LIU, YUAN ZHAO, YU YU, DOU YE, QIAN WANG, ZHAOYAN WANG, ZUO LUAN^*

BIOCELL, Vol.48, No.7, pp. 1115-1126, 2024, DOI:10.32604/biocell.2024.050493

Abstract Introduction: Transplantation of mesenchymal stromal cells (MSCs) is a promising therapy for type 1 diabetes (T1D). However, whether the infused MSCs affect the endoplasmic reticulum stress or subsequent unfolded protein response in β cells remains unclear. Methods: To investigate this, we induced early-onset T1D in non-obese diabetic mice using streptozotocin. Subsequently, T1D mice were randomly assigned to receive either MSCs or phosphate-buffered saline. We observed the in vivo homing of MSCs and assessed their effectiveness by analyzing blood glucose levels, body weight, histopathology, pancreatic protein expression, and serum levels of cytokines, proinsulin, and C-peptide. Results: Infused MSCs… More > Graphic Abstract

Yun-Jung Choi¹, Heewon Song^2,*

International Journal of Mental Health Promotion, Vol.26, No.6, pp. 475-480, 2024, DOI:10.32604/ijmhp.2024.050824

Abstract During the rapid spread of COVID-19, first responders are at risk of being exposed to COVID-19 due to their role in providing first aid and responding to an unspecified number of people. This uncertainty can have adverse mental health effects, such as increased anxiety and fear. This study aimed to investigate the degree of association between fear of COVID-19, obsession with COVID-19, and post-traumatic stress disorder (PTSD) in emergency rescue firefighters. The participants were 150 emergency rescue firefighters working in Region S, Korea. They filled out self-report questionnaires: The data obtained through the Fear of… More >

Binyang Zhao¹, Fengchan Wu², Guojun Cai³, Peiyu Xi², Yulin Guo², Anding Li^2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1345-1363, 2024, DOI:10.32604/phyton.2024.050950

Abstract In order to explore the response mechanism of Passiflora edulis Sims to drought stress, the changes in morphological and physiological traits of Passiflora edulis Sims under different drought conditions were studied. A total of 7 germplasm resources of Passiflora edulis Sims were selected and tested under drought stress by the pot culture method under 4 treatment levels: 75%–80% (Control, CK) of maximum field water capacity, 55%–60% (Light Drought, LD) of maximum field water capacity, i.e., mild drought, 40%–45% (Moderate Drought, MD) of maximum field water capacity, i.e., moderate drought and 30%–35% (Severe Drought, SD) of maximum field water… More >

Cinthia T. Lucero¹, María de los Á. Ruíz², Fabiola Pagliero¹, Carolina Castaño¹, Mariela L. Ambrosino¹, Graciela S. Lorda^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1081-1099, 2024, DOI:10.32604/phyton.2024.050762

Abstract Beneficial microbes can improve soil health by promoting soil structure, nutrient cycling, and disease suppression. In addition, a wide array of rhizospheric microbes are responsible for producing metabolically active compounds including various types of plant growth regulators. So, microbial biodiversity studies could contribute to the improvement of agricultural practices in deprived areas, such as the Pampean semiarid region. The vast majority of studies conducted on endophytic microorganisms have focused on intensive crop legume species. In contrast, little attention has been paid to microorganisms of native legumes, whose ecology is not directly affected by human action.… More >

Muhammad Saleem¹, Jianhua Zhang¹, Muhammad Qasim², Rashid Iqbal³, Li Song^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1325-1344, 2024, DOI:10.32604/phyton.2024.048493

Abstract Variations in the nutrients and water that plants require for metabolism, development, and the maintenance of cellular homeostasis are the main causes of abiotic stress in plants. It has, however, hardly ever been studied how these transporter proteins, such as aquaporin which is responsible for food and water intake in cell plasma membranes, interact with one another. This review aims to explore the interactions between nutrient transporters and aquaporins during water and nutrient uptake. It also investigates how symbiotic relationships influence the plant genome’s responses to regulatory processes such as photoperiodism, senescence, and nitrogen fixation. More >

CARLOS ALBERTO-SILVA^*, BRENDA RUFINO DA SILVA

BIOCELL, Vol.48, No.6, pp. 897-904, 2024, DOI:10.32604/biocell.2024.050443

Abstract Venom snake-derived peptides have multiple biochemical, pharmacological, and toxicological profiles, allowing for the discovery of new medicinal products and therapeutic applications. This review specifically examines the fundamental elements of neuroprotection offered by different oligopeptides derived from snake venom. It also includes a brief evaluation of short peptides that are being considered as potential therapeutic agents. Proline-rich peptides and tryptophyllin family peptides isolated from the crude venom of Viperidae family snakes, specifically Bothrops atrox, Bothrops jararaca, and Bothrops moojeni, have been shown to have pro-survival properties, the ability to reduce oxidative stress, and the ability to promote cell viability More >

Fang Li^1,*, Juan Wu¹, Haiyong Yi², Lihong Wu², Lingyun Du¹, Yuan Zeng¹

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 1015-1030, 2024, DOI:10.32604/fdmp.2023.043256

Abstract Methods for horizontal well spacing calculation in tight gas reservoirs are still adversely affected by the complexity of related control factors, such as strong reservoir heterogeneity and seepage mechanisms. In this study, the stress sensitivity and threshold pressure gradient of various types of reservoirs are quantitatively evaluated through reservoir seepage experiments. On the basis of these experiments, a numerical simulation model (based on the special seepage mechanism) and an inverse dynamic reserve algorithm (with different equivalent drainage areas) were developed. The well spacing ranges of Classes I, II, and III wells in the Q gas More > Graphic Abstract

Makoto Isono, Akinori Sato, Kazuki Okubo, Takako Asano, Tomohiko Asano

Oncology Research, Vol.24, No.5, pp. 327-335, 2016, DOI:10.3727/096504016X14666990347635

Abstract The histone deacetylase (HDAC) inhibitor belinostat increases the amount of unfolded proteins in cells by promoting the acetylation of heat shock protein 90 (HSP90), thereby disrupting its chaperone function. The human immunodeficiency virus protease inhibitor ritonavir, on the other hand, not only increases unfolded proteins by suppressing HSP90 but also acts as a proteasome inhibitor. We thought that belinostat and ritonavir together would induce endoplasmic reticulum (ER) stress and kill renal cancer cells effectively. The combination of belinostat and ritonavir induced drastic apoptosis and inhibited the growth of renal cancer cells synergistically. Mechanistically, the combination More >