Nadezhda Golubkina^1,*, Viktor Kharchenko¹, Ekaterina Krainyuk², Lubov Riff², Vladimir Lapchenko³, Helene Lapchenko³, Anastasia Moldovan¹, Uliana Plotnoikova⁴, Otilia Cristina Murariu⁵, Gianluca Caruso⁶

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4139-4153, 2025, DOI:10.32604/phyton.2025.072328 - 29 December 2025

Abstract Despite their remarkable content of biologically active compounds, highly valuable for human health, wild relatives of Umbelliferous plants show limited utilization. The aim of the present work was the evaluation of the antioxidant status of Anthriscus, Chaerophyllum, and Myrrhoides species gathered in different climatic zones (from Mediterranean to Arctic) and of their suitability to produce valuable functional food for optimizing the human Se status. Among the Crimean plants, A. sylvestris, C. bulbosis, and M. nososa showed the highest antioxidant status, while the lowest was recorded in A. cerefolium and A. caucalis, displaying a significant correlation between the antioxidant activity (AOA) and polyphenols… More >

Manzhu Liao¹, Lan Yang¹, Liehua Tie¹, Qiqiang Guo^1,*, Weilie Zheng^2,*, Jiangrong Li², Yongxia Li²

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3633-3652, 2025, DOI:10.32604/phyton.2025.072725 - 01 December 2025

Abstract Cupressus gigantea is an endemic endangered tree species in the Tibet Plateau, and studying the survival status of the different C. gigantea populations and revealing the main environmental factors that affect the population survival are particularly significant for the conservation and sustainable development of endangered species. Based on the 28 sample plots, the Hierarchical Cluster Method was used to classify the C. gigantea populations into four community types. Age structure diagrams were drawn based on the structure of each community, static life tables and survival curves were compiled, and the future development trends of each age group in… More >

Andrea Panunzio¹, Rossella Orlando¹, Federico Greco^2,3, Giovanni Mazzucato⁴, Floriana Luigina Rizzo¹, Serena Domenica D’Elia¹, Antonio Benito Porcaro⁵, Alessandro Antonelli⁵, Alessandro Tafuri^1,6,*

Canadian Journal of Urology, Vol.32, No.5, pp. 375-384, 2025, DOI:10.32604/cju.2025.066140 - 30 October 2025

Abstract Background: The Barthel Index (BI) measures the level of patient independence in activities of daily living. This review aims to summarize current evidence on the use of the BI in urology, highlighting its potential as a tool for assessing patients prior to surgery. Materials and methods: A comprehensive search of PubMed, Scopus, and Web of Science databases was conducted for studies evaluating the BI in patients undergoing urologic surgery, following Systematic Review and Meta-analyses (PRISMA) guidelines. The BI was investigated both as a descriptor of baseline or postoperative health status and a prognostic indicator. A qualitative… More >

Chiao-Ping Chen^1,2, Yan-Jei Tang^1,2, You-Yan Cai¹, Yi-Ru Pan³, Chun-Nan Yeh^3,4, Wen-Kuan Huang^1,2, Chih-Hong Lo^1,2, Yu-Tien Hsiao^1,2, Hsuan-Jen Shih^1,*, Chiao-En Wu^1,2,4,5,*

Oncology Research, Vol.33, No.11, pp. 3429-3446, 2025, DOI:10.32604/or.2025.066672 - 22 October 2025

Abstract Background: KIT proto-oncogene, receptor tyrosine kinase (KIT, CD117) and platelet-derived growth factor-alpha (PDGFRA) are key drivers of gastrointestinal stromal tumors (GIST), but resistance to targeted therapy often arises from tumor protein p53 (p53) alterations and loss of cell cycle control. However, the role of p53 status in GIST therapeutic potential has rarely been studied, so this study aimed to employ both wild-type and mutant p53 GIST models to investigate how p53 dysfunction influences the efficacy of p53 pathway-targeted therapies. Methods: The efficacy of the mouse double minute 2 homolog (MDM2) inhibitor (HDM201) and the Wee1… More >

Jovan Peškanov^1,*, Sandro Bogdanović², Aleksa Vlku¹, Goran Anačkov¹, Boris Radak¹

Phyton-International Journal of Experimental Botany, Vol.94, No.6, pp. 1769-1786, 2025, DOI:10.32604/phyton.2025.065536 - 27 June 2025

Abstract Since its description, the taxon Ophrys sphegodes subsp. grammica has been considered endemic to Greece. The morphological and chorological data of this taxon have been overlooked because the name has been used as a synonym for O. sphegodes subsp. taurica in most publications and online databases. Recently discovered Ophrys populations in Serbia were identified as O. sphegodes subsp. grammica. As these populations represent the northernmost point of distribution of this taxon, we provided data on the morphology, flowering season, and ecology. To determine the taxonomic status of this taxon, we performed comparative morphological analyses, comparing them to other populations of… More >

CHUCHU ZHANG^1,#, YING LIU^2,#, ZEHUI CHEN¹, YI LIU³, QIYUAN MAO⁴, GE ZHANG⁵, HONGSHENG LIN⁴, JIABIN ZHENG^6,*, HAIYAN LI^1,*

Oncology Research, Vol.33, No.6, pp. 1437-1458, 2025, DOI:10.32604/or.2025.059290 - 29 May 2025

Abstract Objectives: Decades of clinical and fundamental research advancements in oncology have led to significant breakthroughs such as early screening, targeted therapies, and immunotherapy, contributing to reduced mortality rates in cancer patients. Despite these achievements, cancer continues to be a major public health challenge. This study employs bibliometric techniques to visually analyze the English literature on cancer prevention, screening, diagnosis, treatment, and rehabilitation. Methods: We systematically reviewed publications from 01 March 2014, to 01 March 2024, indexed in the Web of Science core collection. Tools such as VOSviewer Version 1.6.20 is characterized by its core idea… More > Graphic Abstract

MIAO YAN¹, DONGXUAN CHI², WEN WANG³, PEI PEI⁴, MIN XIE¹, SHUANGLING LI^1,*

BIOCELL, Vol.49, No.5, pp. 893-906, 2025, DOI:10.32604/biocell.2025.063622 - 27 May 2025

Abstract Background: Transcription factor Krüppel-like factor 3 (KLF3) may be involved in regulating inflammation and lymphocyte function. Immune dysfunction in sepsis involves both hyper-inflammation and immunosuppression. However, studies on T-lymphocyte KLF3 expression in sepsis are lacking. Methods: We induced sepsis in mice via cecal ligation and puncture (CLP), and their survival rate over 7 days was evaluated. To identify the immune status of these mice, we assessed their cytokine levels, organ damage scores, and splenic T-lymphocyte phenotype. Finally, T-lymphocyte KLF3 expression was detected through flow cytometry. Results: Over the 7 days of observation, septic mice demonstrated 64.7%… More >

Xiaolin Zhang¹, Shujie Li², Enguo Wang^1,*

Journal of Psychology in Africa, Vol.35, No.1, pp. 75-81, 2025, DOI:10.32604/jpa.2025.065767 - 30 April 2025

Abstract This study examined the relationship between leader-employee calling congruence on employees’ voice behaviour. Participants were 173 leader-employee dyads from the Chinese service industry. They completed online surveys on calling, perceived insider status, and voice behaviour. Results from polynomial regression and response surface analysis showed that employees perceived insider status to be weaker with the low leader-low subordinate calling congruence, and stronger with high leader and high subordinate calling congruence. Employees perceived insider status is stronger in low leader and high subordinate calling incongruence compared with high leader and low subordinate calling incongruence. Perceived insider status More >

Tao Zheng¹, Wenyi Tang^1,2,4,*, Xingshu Chen^1,3,4, Changxiang Shen^1,3,4

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 1687-1701, 2024, DOI:10.32604/cmc.2024.056141 - 15 October 2024

Abstract The security performance of cloud services is a key factor influencing users’ selection of Cloud Service Providers (CSPs). Continuous monitoring of the security status of cloud services is critical. However, existing research lacks a practical framework for such ongoing monitoring. To address this gap, this paper proposes the first Non-Collaborative Container-Based Cloud Service Operation State Continuous Monitoring Framework (NCCMF), based on relevant standards. NCCMF operates without the CSP’s collaboration by: 1) establishing a scalable supervisory index system through the identification of security responsibilities for each role, and 2) designing a Continuous Metrics Supervision Protocol (CMA) More >

Shahin Imran^1,2,*, Md. Asif Mahamud³, Newton Chandra Paul¹, Prosenjit Sarker⁴, Md. Tahjib-Ul-Arif⁵, Nazmul Islam⁵, Mohammad Saidur Rhaman⁶, Saleh H. Salmen⁷, Sulaiman Ali Alharbi⁷, Mohammad Javed Ansari⁸, Mohammed Ali Alshehri⁹, Akbar Hossain^10,*

Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2251-2266, 2024, DOI:10.32604/phyton.2024.055736 - 30 September 2024

Abstract Soybean (Glycine max) is a potential legume crop, but it cannot thrive in mild salinity. Salicylic acid (SA) is a renowned plant growth hormone that improves tolerance to saline conditions. Hence, the study was performed to understand the functions of priming seeds and supplementation of SA in modulating salt tolerance in soybean seedlings. When exposed to salt stress, soybean seedlings showed considerably higher contents of hydrogen peroxide (H₂O₂) and malondialdehyde (MDA) while having decreased germination and growth factors, water contents, and photosynthetic pigments. The germination rate, final germination percentage, germination index, germination energy, and seed vigor index… More >