YUSHI YANG^1,#, CHUJIAO HU^2,#, SHAN LEI³, XIN BAO³, ZHIRUI ZENG^3,*, WENPENG CAO^4,*

Oncology Research, Vol.32, No.12, pp. 1921-1934, 2024, DOI:10.32604/or.2024.046191 - 13 November 2024

Abstract Background: The heterogeneity of prognosis and treatment benefits among patients with gliomas is due to tumor microenvironment characteristics. However, biomarkers that reflect microenvironmental characteristics and predict the prognosis of gliomas are limited. Therefore, we aimed to develop a model that can effectively predict prognosis, differentiate microenvironment signatures, and optimize drug selection for patients with glioma. Materials and Methods: The CIBERSORT algorithm, bulk sequencing analysis, and single-cell RNA (scRNA) analysis were employed to identify significant cross-talk genes between M2 macrophages and cancer cells in glioma tissues. A predictive model was constructed based on cross-talk gene expression, and… More >

Shahlaa Mashhadani^1,*, Wisal Hashim Abdulsalam¹, Oday Ali Hassen², Saad M. Darwish³

Intelligent Automation & Soft Computing, Vol.39, No.5, pp. 805-828, 2024, DOI:10.32604/iasc.2024.054611 - 31 October 2024

Abstract Signature verification involves vague situations in which a signature could resemble many reference samples or might differ because of handwriting variances. By presenting the features and similarity score of signatures from the matching algorithm as fuzzy sets and capturing the degrees of membership, non-membership, and indeterminacy, a neutrosophic engine can significantly contribute to signature verification by addressing the inherent uncertainties and ambiguities present in signatures. But type-1 neutrosophic logic gives these membership functions fixed values, which could not adequately capture the various degrees of uncertainty in the characteristics of signatures. Type-1 neutrosophic representation is also… More >

Xin Cong, Lanjin Feng^*, Lingling Zi

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 663-684, 2024, DOI:10.32604/cmc.2024.054372 - 15 October 2024

Abstract In the digital information age, distributed file storage technologies like the InterPlanetary File System (IPFS) have gained considerable traction as a means of storing and disseminating media content. Despite the advantages of decentralized storage, the proliferation of decentralized technologies has highlighted the need to address the issue of file ownership. The aim of this paper is to address the critical issues of source verification and digital copyright protection for IPFS image files. To this end, an innovative approach is proposed that integrates blockchain, digital signature, and blind watermarking. Blockchain technology functions as a decentralized and… More >

Ang Liu¹, Qing Zhang², Shengwei Xu^3,*, Huamin Feng⁴, Xiu-bo Chen⁵, Wen Liu¹

CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 1727-1751, 2024, DOI:10.32604/cmc.2024.051233 - 18 July 2024

Abstract The Internet of Things (IoT) is a network system that connects physical devices through the Internet, allowing them to interact. Nowadays, IoT has become an integral part of our lives, offering convenience and smart functionality. However, the growing number of IoT devices has brought about a corresponding increase in cybersecurity threats, such as device vulnerabilities, data privacy concerns, and network susceptibilities. Integrating blockchain technology with IoT has proven to be a promising approach to enhance IoT security. Nevertheless, the emergence of quantum computing poses a significant challenge to the security of traditional classical cryptography used… More >

Jane Kim¹, Soojin Lee¹, Chan Yeob Yeun², Seung-Hyun Seo^1,3,*

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 3495-3518, 2024, DOI:10.32604/cmc.2024.050461 - 20 June 2024

Abstract As big data, Artificial Intelligence, and Vehicle-to-Everything (V2X) communication have advanced, Intelligent Transportation Systems (ITS) are being developed to enable efficient and safe transportation systems. Electronic Toll Collection (ETC), which is one of the services included in ITS systems, is an automated system that allows vehicles to pass through toll plazas without stopping for manual payment. The ETC system is widely deployed on highways due to its contribution to stabilizing the overall traffic system flow. To ensure secure and efficient toll payments, designing a distributed model for sharing toll payment information among untrusted toll service… More >

Fangjun Luan^1,2,3, Xuewen Mu^1,2,3, Shuai Yuan^1,2,3,*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 695-712, 2024, DOI:10.32604/cmc.2024.048502 - 25 April 2024

Abstract Online Signature Verification (OSV), as a personal identification technology, is widely used in various industries. However, it faces challenges, such as incomplete feature extraction, low accuracy, and computational heaviness. To address these issues, we propose a novel approach for online signature verification, using a one-dimensional Ghost-ACmix Residual Network (1D-ACGRNet), which is a Ghost-ACmix Residual Network that combines convolution with a self-attention mechanism and performs improvement by using Ghost method. The Ghost-ACmix Residual structure is introduced to leverage both self-attention and convolution mechanisms for capturing global feature information and extracting local information, effectively complementing whole and… More >

Hongliang Tian, Jiaming Wang^*

CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 1611-1629, 2024, DOI:10.32604/cmc.2023.046698 - 27 February 2024

Abstract Blockchain, known for its secure encrypted ledger, has garnered attention in financial and data transfer realms, including the field of energy trading. However, the decentralized nature and identity anonymity of user nodes raise uncertainties in energy transactions. The broadcast consensus authentication slows transaction speeds, and frequent single-point transactions in multi-node settings pose key exposure risks without protective measures during user signing. To address these, an alliance blockchain scheme is proposed, reducing the resource-intensive identity verification among nodes. It integrates multi-signature functionality to fortify user resources and transaction security. A novel multi-signature process within this framework… More >

Cai Ming Liu^1,2,3, Yan Zhang^1,2,*, Zhihui Hu^1,2, Chunming Xie¹

CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 2361-2389, 2024, DOI:10.32604/cmc.2023.045282 - 27 February 2024

Abstract Artificial immune detection can be used to detect network intrusions in an adaptive approach and proper matching methods can improve the accuracy of immune detection methods. This paper proposes an artificial immune detection model for network intrusion data based on a quantitative matching method. The proposed model defines the detection process by using network data and decimal values to express features and artificial immune mechanisms are simulated to define immune elements. Then, to improve the accuracy of similarity calculation, a quantitative matching method is proposed. The model uses mathematical methods to train and evolve immune More >

DAIXIN ZHAO¹, QINGYU WANG², JIANBO WANG^1,*

BIOCELL, Vol.48, No.2, pp. 271-281, 2024, DOI:10.32604/biocell.2023.029094 - 23 February 2024

Abstract Background: Esophageal cancer (ESCA) is a common digestive tract tumor. As a result, optimization of the early diagnosis of ESCA and identifying the contributing prognostic genes is urgently required. Herein, the prognosis of mitochondrial autophagy-related genes was analyzed in different subtypes of ESCA, and prognostic models were constructed to identify the immune cell infiltration with significant differences between subtypes. Methods: The Cancer Genome Atlas database was searched to download 185 ESCA samples, covering gene expression level data and clinical follow-up data, and 179 samples from the Gene Expression Omnibus database for subsequent validation analysis. The… More >

QIOU GU¹, CHUILIN LAI¹, XIAO GUAN¹, JING ZHU², TIAN ZHAN¹, JIANPING ZHANG^1,*

BIOCELL, Vol.48, No.2, pp. 253-269, 2024, DOI:10.32604/biocell.2023.028336 - 23 February 2024

Abstract Objectives: Colorectal cancer (CRC) is a serious threat to human health worldwide. Oxaliplatin is a platinum analog and is widely used to treat CRC. However, resistance to oxaliplatin restricts its effectiveness and application while its target recognition and mechanism of action also remain unclear. Therefore, we aimed to develop an oxaliplatin-resistant prognostic model to clarify these aspects. Methods: We first obtained oxaliplatin-resistant and parental cell lines, and identified oxaliplatin-resistant genes using RNA sequencing (RNA-seq) and differential gene analysis. We then acquired relevant data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases.… More > Graphic Abstract