Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (1)
  • Open Access

    ARTICLE

    MDCK cells express serotonin-regulable 11ß-hydroxysteroid dehydrogenase type 2

    MARISA L. ZALLOCCHI*1, MARIA C. DAMASCO1, JUAN C. CALVO1,2, CARLOS P. LANTOS1, LAURA B. MATKOVIC1

    BIOCELL, Vol.30, No.3, pp. 469-477, 2006, DOI:10.32604/biocell.2006.30.469

    Abstract Prior to this work, we found that adrenal as well as extra-adrenal factors activate the response of renal 11ß-hydroxysteroid dehydrogenase 2 to stressful situations. These results -showing ways through which the organism hinders the pathological occupation of mineralocorticoid receptors by glucocorticoids leading to sodium retention and hypertension- prompted the present study on the nature of the above-mentioned extraadrenal factors. Serotonin was chosen because of its properties as a widely distributed neurohormone, known to interact with glucocorticoids at many sites, also exhibiting increased levels and effects under stressful situations. We studied serotonin effects on 11ß-hydroxysteroid dehydrogenase… More >

Displaying 1-10 on page 1 of 1. Per Page