Yuhua Gong1, Shilei Hao1,*, Bochu Wang1,*
Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 143-143, 2019, DOI:10.32604/mcb.2019.07095
Abstract The mechanical response of brain tissue closely relates to cerebral blood flow and brain diseases. During intracerebral haemorrhage (ICH), a mass effect occurs during the initial bleeding. As the hematoma increases, the haematoma mass effect continues to squeeze the brain tissue mechanically, which can even lead to the formation of fatal cerebral hernia. However, fewer studies have focused on the brain damage mechanisms and treatment approaches associated with mass effects compared to the secondary brain injuries after ICH, which may be a result of the absence of acceptable animal models mimicking a mass effect. Thus,… More >
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