Xingbang Li^1,#, Xuan Zheng^2,#, Bowen Jin¹, Yunyan Li¹, Yongyu Shao¹, Xiaoxian Deng¹, Dingyang Li¹, Shanshan Li¹, Hongmei Zhou¹, Jie Zhang³, Xianya Zhang⁴, Qunshan Shen¹, Gangcheng Zhang^2,*

Congenital Heart Disease, Vol.18, No.4, pp. 489-489, 2023, DOI:10.32604/chd.2023.031413

Abstract This article has no abstract. More >

Abdulghani M. Abdulghani, Mokhles M. Abdulghani, Wilbur L. Walters, Khalid H. Abed^*

Journal on Artificial Intelligence, Vol.5, pp. 1-14, 2023, DOI:10.32604/jai.2023.039786

Abstract Autonomous agents can explore the environment around them when equipped with advanced hardware and software systems that help intelligent agents minimize collisions. These systems are developed under the term Artificial Intelligence (AI) safety. AI safety is essential to provide reliable service to consumers in various fields such as military, education, healthcare, and automotive. This paper presents the design of an AI safety algorithm for safe autonomous navigation using Reinforcement Learning (RL). Machine Learning Agents Toolkit (ML-Agents) was used to train the agent with a proximal policy optimizer algorithm with an intrinsic curiosity module (PPO + ICM). This training aims to improve AI… More >

Xingbang Li^1,#, Xuan Zheng^2,#, Bowen Jin¹, Yunyan Li¹, Yongyu Shao¹, Xiaoxian Deng¹, Dingyang Li¹, Shanshan Li¹, Hongmei Zhou¹, Jie Zhang³, Xianya Zhang⁴, Qunshan Shen¹, Gangcheng Zhang^2,*

Congenital Heart Disease, Vol.18, No.3, pp. 373-385, 2023, DOI:10.32604/chd.2023.028979

Abstract Background: Transcatheter closure of patent foramen ovale (PFO) has been widely accepted as a highly effective way to treat high-risk PFO-related diseases. However, traditional non-degradable occluders made of metal alloys will permanently exist in the body, resulting in thrombosis, valve damage, hemolysis, arrhythmia, or other complications. The biodegradable PFO occluder developed by Shanghai Mallow Medical Instrument Co., Ltd., China can be fully absorbed and degrade into nontoxic ingredients, reducing postoperative complications. Objectives: To study the safety and efficacy of biodegradable PFO occluders in treating PFO. Methods: This single-center clinical trial collected 30 patients treated with a biodegradable PFO occluder. The… More > Graphic Abstract

Henry P. Foote¹, Huali Wu², Stephen J. Balevic^1,2, Elizabeth J. Thompson^1,2, Kevin D. Hill^1,2, Eric M. Graham³, Christoph P. Hornik^1,2, Karan R. Kumar^1,2,*

Congenital Heart Disease, Vol.18, No.3, pp. 295-313, 2023, DOI:10.32604/chd.2023.026262

Abstract Background: Infants undergoing cardiac surgery with cardiopulmonary bypass (CPB) frequently receive intra-operative methylprednisolone (MP) to suppress CPB-related inflammation; however, the optimal dosing strategy and efficacy of MP remain unclear. Methods: We retrospectively analyzed all infants under 90 days-old who received intra-operative MP for cardiac surgery with CPB from 2014–2017 at our institution. We combined real-world dosing data from the electronic health record (EHR) and two previously developed population pharmacokinetic/pharmacodynamic models to simulate peak concentration (Cmax) and area under the concentration-time curve for 24 h (AUC24) for MP and the inflammatory cytokines interleukin-6 (IL-6) and interleukin-10 (IL-10). We evaluated the relationships… More > Graphic Abstract

Sharad Saxena¹, Shailendra Mishra^2,*, Mohammed Baljon^2,*, Shamiksha Mishra³, Sunil Kumar Sharma², Prakhar Goel¹, Shubham Gupta¹, Vinay Kishore¹

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 1027-1045, 2023, DOI:10.32604/cmc.2023.039677

Abstract In recent years, the growth of female employees in the commercial market and industries has increased. As a result, some people think travelling to distant and isolated locations during odd hours generates new threats to women’s safety. The exponential increase in assaults and attacks on women, on the other hand, is posing a threat to women’s growth, development, and security. At the time of the attack, it appears the women were immobilized and needed immediate support. Only self-defense isn’t sufficient against abuse; a new technological solution is desired and can be used as quickly as hitting a switch or button.… More >

Ammar Almomani^1,2,*, Mohammad Alauthman³, Amal Malkawi², Hadeel Shwaihet², Batool Aldigide², Donia Aldabeek², Karmen Abu Hamoodeh²

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 415-436, 2023, DOI:10.32604/cmc.2023.036266

Abstract People’s lives have become easier and simpler as technology has proliferated. This is especially true with the Internet of Things (IoT). The biggest problem for blind people is figuring out how to get where they want to go. People with good eyesight need to help these people. Smart shoes are a technique that helps blind people find their way when they walk. So, a special shoe has been made to help blind people walk safely without worrying about running into other people or solid objects. In this research, we are making a new safety system and a smart shoe for… More >

Gang Xiang^1,2, Xiaoyu Cheng³, Wei He^3,4,*, Peng Han³

Computer Systems Science and Engineering, Vol.47, No.1, pp. 273-298, 2023, DOI:10.32604/csse.2023.037892

Abstract A liquid launch vehicle is an important carrier in aviation, and its regular operation is essential to maintain space security. In the safety assessment of fluid launch vehicle body structure, it is necessary to ensure that the assessment model can learn self-response rules from various uncertain data and not differently to provide a traceable and interpretable assessment process. Therefore, a belief rule base with interpretability (BRB-i) assessment method of liquid launch vehicle structure safety status combines data and knowledge. Moreover, an innovative whale optimization algorithm with interpretable constraints is proposed. The experiments are carried out based on the liquid launch… More >

Huiling Fu¹, Mijun Peng², Qiuwen Tang², Haojun Liang², Yanli Liang², Jiali Fang^2,*, Xuesong Wang^2,*

Journal of Renewable Materials, Vol.11, No.7, pp. 3091-3114, 2023, DOI:10.32604/jrm.2023.026689

Abstract To ensure the export quality of Eucommia ulmoides leaf extract (ELE) and facilitate E. ulmoides leaf inclusion in the directory of traditional Chinese health foods, an overall safety assessment of ELE was performed, including genotoxicity and long-term toxicity, according to the national food safety standards of China. No variations in the reverse mutation number of the nominal bacterial strains were observed under ELE treatment in comparison with the solvent control. Additionally, the micronucleus rates of in vivo mammalian erythrocytes and in vitro mammalian cells under ELE treatment were equivalent to or significantly lower than those of the solvent control. The… More > Graphic Abstract

Pedro Montenegro^1,*, Raphael Heleno², Hermes Carvalho², Diogo Ribeiro³, Rui Calçada¹, Chris Baker⁴

The International Conference on Computational & Experimental Engineering and Sciences, Vol.24, No.1, pp. 1-2, 2022, DOI:10.32604/icces.2022.08678

Abstract This work consists of evaluating the impact of the most relevant characteristics of railway vehicles, namely geometric, mechanical and aerodynamic properties, in their runnability in the presence of strong winds, more precisely in the risk of derailment. Such objective is achieved by performing several dynamic with a non-linear vehicle-structure interaction model developed by the authors [1,2] and used in other works in this field [3,4], which allows the evaluation of the wheel-rail contact forces and, consequently, the unloading index, as suggested by the European Norm EN 14067-6 [5]. The calculations are carried out for several scenarios characterized by different train… More >

Christopher C. Rosser, Wilbur L. Walters, Abdulghani M. Abdulghani, Mokhles M. Abdulghani, Khalid H. Abed^*

Journal on Artificial Intelligence, Vol.4, No.4, pp. 261-277, 2022, DOI:10.32604/jai.2022.039703

Abstract Intrinsic motivation helps autonomous exploring agents traverse a larger portion of their environments. However, simulations of different learning environments in previous research show that after millions of timesteps of successful training, an intrinsically motivated agent may learn to act in ways unintended by the designer. This potential for unintended actions of autonomous exploring agents poses threats to the environment and humans if operated in the real world. We investigated this topic by using Unity’s Machine Learning Agent Toolkit (ML-Agents) implementation of the Proximal Policy Optimization (PPO) algorithm with the Intrinsic Curiosity Module (ICM) to train autonomous exploring agents in three… More >