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    ARTICLE

    The ovary of Lagostomus maximus (Mammalia, Rodentia): an analysis by confocal microscopy

    MARÍA B. ESPINOSA2 , NICOLÁS A. FRAUNHOFFER1 , NOELIA P. LEOPARDO1 , ALFREDO D. VITULLO2 AND MIGUEL A. WILLIS1

    BIOCELL, Vol.35, No.2, pp. 37-42, 2011, DOI:10.32604/biocell.2011.35.037

    Abstract Lagostomus maximus is a notable mammalian model for reproductive studies. Females have an extremely high ovulation rate, which is due to down-regulation of the follicular apoptosis pathway, which ensures a large pool of developing follicles. This large pool is supported by the convoluted anatomy of the mature ovary, whose germinal tissue is found in irregularly curved ridges throughout the cortex. Medullary tissue is restricted to a minimum. Lyso Tracker Red reconstruction under confocal laser scanning microscopy was used to recognize and measure all follicular stages from primordial to antral. Unlike most mammals in which early primordial More >

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