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  • Open Access

    ARTICLE

    Associated Factors of Anxiety Symptoms in Patients with Keratinocyte Carcinoma: A Cross-Sectional Study

    Qian Liu1,#, Hui Zhang1,#, Juan Gao2, Meiping Sha1, Lijun Shen1, Xianfeng Cheng3,*, Hao Chen4,*

    Psycho-Oncologie, Vol.18, No.3, pp. 213-221, 2024, DOI:10.32604/po.2024.052607 - 12 September 2024

    Abstract Background: Keratinocyte carcinoma (KC) is a common malignancy characterized by a high recurrence rate and considerable psychological distress. The incidence of KC is increasing in China, raising concerns about its psychological consequences and adverse effects on quality of life. Demographic and clinical factors are thought to influence mental health outcomes in these patients. Nonetheless, data on the prevalence of anxiety in Chinese patients with KC and the factors associated with this anxiety are notably lacking. Therefore, a comprehensive investigation into the anxiety of patients with KC is imperative. Objective: This study aimed to investigate the… More >

  • Open Access

    ARTICLE

    Cardiovascular Disease Prediction Using Risk Factors: A Comparative Performance Analysis of Machine Learning Models

    Adil Hussain1,*, Ayesha Aslam2

    Journal on Artificial Intelligence, Vol.6, pp. 129-152, 2024, DOI:10.32604/jai.2024.050277 - 21 May 2024

    Abstract The diagnosis and prognosis of cardiovascular diseases are critical medical responsibilities that assist cardiologists in correctly classifying patients and treating them accordingly. The utilization of machine learning in the medical domain has witnessed a notable surge due to its ability to discern patterns from vast amounts of data. Machine learning algorithms that can categorize cases of cardiovascular illness may help doctors reduce the number of wrong diagnoses. This research investigates the efficacy of different machine learning algorithms in predicting cardiovascular disease in accordance with risk factors. This study utilizes a variety of machine learning models, More >

  • Open Access

    ARTICLE

    Risk Factors for Abuse in Children with Congenital Heart Disease Presenting at a Pediatric Tertiary Care Hospital

    Kristi K. Westphaln1,2,*, Karen Kay Imagawa2,3, Lorena Espinosa Smith1,4, Julia Srivastava5, Nancy A. Pike1,5

    Congenital Heart Disease, Vol.18, No.6, pp. 657-670, 2023, DOI:10.32604/chd.2023.044179 - 19 January 2024

    Abstract Background: Congenital heart disease (CHD) is a chronic medical condition often diagnosed at birth and requires surgical intervention, multiple hospitalizations, and lifelong care. This can put significant stress on the family, leading to altered maternal mental health, bonding and attachment issues, and the potential for child abuse. The purpose of this study is to explore the characteristics of a sample of young children with CHD who experienced hospitalization with concurrent concern for child abuse in a free-standing pediatric tertiary care hospital. Methods: Electronic medical records were reviewed for children aged 0–5 years old who were… More >

  • Open Access

    REVIEW

    Molecular basis of COVID-19, ARDS and COVID-19-associated ARDS: Diagnosis pathogenesis and therapeutic strategies

    PRIYADHARSHINI THANJAVUR SRIRAMAMOORTHI1,2, GAYATHRI GOPAL1,2, SHIBI MURALIDAR1,2, SAI RAMANAN ESWARAN1,2, DANUSH NARAYAN PANNEERSELVAM1,2, BHUVANESWARAN MEIYANATHAN1,2, SRICHANDRASEKAR THUTHIKKADU INDHUPRAKASH1,2, SENTHIL VISAGA AMBI1,2,*

    BIOCELL, Vol.47, No.11, pp. 2335-2350, 2023, DOI:10.32604/biocell.2023.029379 - 27 November 2023

    Abstract The novel coronavirus pneumonia (COVID-19) is spreading worldwide and threatening people greatly. The routes by which SARS-CoV-2 causes lung injury have grown to be a major concern in the scientific community since patients with new Coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV-2) have a high likelihood of developing acute respiratory distress syndrome (ARDS) in severe cases. The mortality rate of COVID-19 has increased over the period due to rapid spread, and it becomes crucial to understand the disease epidemiology, pathogenic mechanisms, and suitable treatment strategies. ARDS is a respiratory disorder and is one of the… More > Graphic Abstract

    Molecular basis of COVID-19, ARDS and COVID-19-associated ARDS: Diagnosis pathogenesis and therapeutic strategies

  • Open Access

    ARTICLE

    Ventricular Arrhythmia in the Fontan Circulation: Prevalence, Risk Factors and Clinical Implications

    Charis Tan1,2 , Diana Zannino3, Carley Clendenning3, Sophie Offen4, Thomas L. Gentles5, Julian Ayer6, David Tanous7, Vishva Wijesekera8, Leeanne Grigg9, David Celermajer2,4,10, Mark McGuire2,4 , Yves d’Udekem3,11,12, Rachael Cordina2,4,10,*

    Congenital Heart Disease, Vol.18, No.5, pp. 507-523, 2023, DOI:10.32604/chd.2023.028829 - 10 November 2023

    Abstract Objective: Sudden cardiac death (SCD) and malignant ventricular arrhythmia (VA) are increasingly recognized as important issues for people living with a Fontan circulation, but data are lacking. We sought to characterize the cohort who had sudden cardiac death, most likely related to VA and/or documented VA in the Australia and New Zealand Fontan Registry including risk factors and clinical outcomes. Methods: A retrospective cohort study was performed. Inclusion criteria were documented non-sustained ventricular tachycardia, sustained ventricular tachycardia, ventricular fibrillation, resuscitated cardiac arrest or SCD > 30 days post-Fontan completion. Results: Of 1611 patients, 20 (1.2%) had VA;… More >

  • Open Access

    ARTICLE

    Analysis of Risk Factors for Early Mortality in Surgical Shunt Palliation: Time for a Change?

    François-Xavier Van Vyve1, Karlien Carbonez2, Jelena Hubrechts2, Geoffroy de Beco1, Jean E. Rubay1, Mona Momeni3, Thierry Detaille4, Alain J. Poncelet1,*

    Congenital Heart Disease, Vol.18, No.5, pp. 539-550, 2023, DOI:10.32604/chd.2023.042344 - 10 November 2023

    Abstract Objectives: Over the last decade, neonatal repair has been advocated for many congenital heart diseases. However, specific subgroups of complex congenital heart disease still require temporary palliation for which both surgical and endovascular techniques are currently available. We reviewed our institutional experience with shunt palliation with an emphasis on risk factors for early mortality. Methods: This is a single-center retrospective study on 175 patients undergoing surgery for central shunt or modified Blalock-Taussig shunt. All data were extracted from a prospectively collected computerized database. We identified risk factors for early mortality by uni- and multi-variable analysis.… More >

  • Open Access

    ARTICLE

    Predicting Dementia Risk Factors Based on Feature Selection and Neural Networks

    Ashir Javeed1,2, Ana Luiza Dallora2, Johan Sanmartin Berglund2,*, Arif Ali4, Peter Anderberg2,3, Liaqat Ali5

    CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 2491-2508, 2023, DOI:10.32604/cmc.2023.033783 - 31 March 2023

    Abstract Dementia is a disorder with high societal impact and severe consequences for its patients who suffer from a progressive cognitive decline that leads to increased morbidity, mortality, and disabilities. Since there is a consensus that dementia is a multifactorial disorder, which portrays changes in the brain of the affected individual as early as 15 years before its onset, prediction models that aim at its early detection and risk identification should consider these characteristics. This study aims at presenting a novel method for ten years prediction of dementia using on multifactorial data, which comprised 75 variables.… More >

  • Open Access

    REVIEW

    Suicide in Digestive System Cancers: A Scoping Review

    Jie Chen1,2, Xiaoping Ding1,2, Xin Peng3, Deying Hu1,3,*

    International Journal of Mental Health Promotion, Vol.25, No.1, pp. 1-20, 2023, DOI:10.32604/ijmhp.2022.022578 - 29 November 2022

    Abstract Digestive system cancers are important causes of morbidity and mortality worldwide. Cancer patients are more likely to commit suicide. The objective of this scoping review is to provide a comprehensive and updated summary of the existing literature on suicide among patients with digestive system cancers to identify the incidence and risk factors relevant to suicide in these populations. The PRISMA-Scr (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension protocol for scoping reviews) protocol was used. The review was based on relevant articles published prior to January 2022 in databases of Web of Science and… More >

  • Open Access

    REVIEW

    Epidemiology of Breast Cancer

    Chao Shang, Dongkui Xu*

    Oncologie, Vol.24, No.4, pp. 649-663, 2022, DOI:10.32604/oncologie.2022.027640 - 31 December 2022

    Abstract All over the world, the most common malignancy in women is breast cancer. Breast cancer is also a significant factor of death in women. In 2020, approximately 2.3 million cases of breast cancer were newly diagnosed in women globally, and approximately 685,000 people died. Breast cancer incidence varies by region around the world, but it is all increasing. According to the current morbidity and mortality trend of breast cancer, it is estimated that by 2030, the number of incidence and deaths of breast cancer will reach 2.64 million and 1.7 million, respectively. The age-standardized incidence… More >

  • Open Access

    ARTICLE

    Incidence and Related Risk Factors of Junctional Ectopic Tachycardia in Infants after Cardiac Surgery for Congenital Heart Disease

    Jae Hee Seol1,4,#, Se Yong Jung1,#, Jae Young Choi1, Han Ki Park2, Young Hwan Park2, Nam Kyun Kim1,3,*

    Congenital Heart Disease, Vol.17, No.5, pp. 569-578, 2022, DOI:10.32604/chd.2022.018436 - 06 September 2022

    Abstract Objective: Junctional ectopic tachycardia is common after cardiac surgery for congenital heart disease. However, its incidence and related risk factors in infants after cardiac surgery are not well known. The objective of this study was to determine the overall incidence and related risk factors for junctional ectopic tachycardia in neonates and infants. Methods: We enrolled a total of 271 patients aged <1 year who underwent open cardiac surgery at Severance Cardiovascular Hospital from January 2018 to December 2020. Exclusion criteria were immediate postoperative mortality, other arrhythmias detected in the perioperative period, and prematurity. Result: The overall incidence of… More >

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