Weiliang Qi^1,2,3,4,*, Wancang Sun⁵, Li Ma⁵, Xiaolong Li¹, Haiqing Liu¹, Cairong Yang⁶, Ziyao Wei¹

Phyton-International Journal of Experimental Botany, Vol.94, No.3, pp. 739-762, 2025, DOI:10.32604/phyton.2025.060712 - 31 March 2025

Abstract Brassica napus L. (B. napus), recognized as a significant cash and oil crop, faces challenges in popularization and application in northern China due to its limited cold resistance. Clarifying the mechanism of cold stress on gene regulation and signal transduction in B. napus is crucial. To address these issues, we conducted transcriptome sequencing and gene expression analysis, along with gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathway profiling under natural (25°C) and cold (4°C) conditions in cold tolerant 16VHNTS309 and weak cold-resistant Tianyou 2238 B. napus seedlings. Enhanced genomic annotation was achieved through additional sequencing.… More >

Shanlong Che, Guangliang Qu, Jin Ding^*, Guochen Wang, Yunyan Hao, Dianchen Li

Journal of Polymer Materials, Vol.42, No.1, pp. 221-236, 2025, DOI:10.32604/jpm.2025.058587 - 27 March 2025

Abstract Acrylonitrile–butadiene–styrene (ABS) is the main material used in fused deposition modeling (FDM), which has good toughness and strength, but the single ABS material has poor heat resistance, which tends to cause warping and deformation during the printing process. Polycarbonate (PC) exhibits good performance in heat resistance, allowing it to maintain stable performance at higher temperatures. In this work, PC was used as a blending modifier to prepare five kinds of ABS/PC composite filaments, and the mechanical and thermal properties of the ABS/PC (Acrylonitrile–butadiene–styrene/Polycarbonate) composite filaments were studied and analyzed. Results showed that the glass transition… More >

Hongjuan Guo¹, Dan Liu^1,2, Ruyu Yan^1,2, Tianjing Zhang³, Kecheng Zhou^1,2,*, Minxia Liu^1,*

BIOCELL, Vol.49, No.3, pp. 483-502, 2025, DOI:10.32604/biocell.2025.062143 - 31 March 2025

Abstract Objectives: Non-small cell lung cancer (NSCLC) represents a formidable malignancy characterized by its marked metastatic potential and intrinsic resistance to therapeutic interventions. The identification of potential biomarkers delineating the progression and metastatic cascade of NSCLC assumes paramount importance in fostering advancements toward enhanced patient outcomes and prognostic stratification. Methods: The expression level of the actin-related protein 2/3 complex; subunit 1A (ARPC1A) in NSCLC was evaluated using The Cancer Genome Atlas (TCGA) and Gene Expression Profiling Interactive Analysis (GEPIA) databases; along with the LinkedOmics database for co-expression genes. Further verification of ARPC1A expression in normal lung cells… More >

Xiang Zhang^1,2,*, Shenyan Han^1,2, Wenbin Huang^1,2, Daoyong Fu^1,2

CMC-Computers, Materials & Continua, Vol.83, No.1, pp. 1149-1171, 2025, DOI:10.32604/cmc.2025.060876 - 26 March 2025

Abstract Generative image steganography is a technique that directly generates stego images from secret information. Unlike traditional methods, it theoretically resists steganalysis because there is no cover image. Currently, the existing generative image steganography methods generally have good steganography performance, but there is still potential room for enhancing both the quality of stego images and the accuracy of secret information extraction. Therefore, this paper proposes a generative image steganography algorithm based on attribute feature transformation and invertible mapping rule. Firstly, the reference image is disentangled by a content and an attribute encoder to obtain content features… More >

LUIZ FERNANDO LOPES SILVA^1,#, JULIETE NATHALI SCHOLL^1,#, AUGUSTO FERREIRA WEBER¹, CAMILA KEHL DIAS¹, PAULINE RAFAELA PIZZATO², VINíCIUS PIERDONá LIMA¹, JEAN SÉVIGNY^3,4, ANA MARIA OLIVEIRA BATTASTINI¹, FABRÍCIO FIGUEIRÓ^1,2,*

Oncology Research, Vol.33, No.4, pp. 951-964, 2025, DOI:10.32604/or.2024.055508 - 19 March 2025

Abstract Objectives: Glioblastoma (GB) is a grade IV glial tumor characterized by high malignancy and dismal prognosis, primarily due to high recurrence rates and therapeutic resistance. The epidermal growth factor receptor (EGFR), a receptor tyrosine kinase (RTK), regulates signaling pathways, including cell growth, proliferation, survival, migration, and cell death. Many cancers utilize immune checkpoints (ICs) to attenuate immune responses. CD73 is an enzyme that functions as an IC by hydrolyzing AMP to adenosine, suppressing immune cells in the tumor microenvironment. However, the role of CD73 in resistance to EGFR inhibitors is poorly understood. This study aims… More >

JIAHENG WEI¹, LIANGMING ZHU^2,*

Oncology Research, Vol.33, No.4, pp. 863-872, 2025, DOI:10.32604/or.2024.054201 - 19 March 2025

Abstract Lung cancer is one of the main causes of cancer-related deaths globally, with non-small cell lung cancer (NSCLC) being the most prevalent histological subtype of lung cancer. Glutathione peroxidase 4 (GPX4) is a crucial antioxidant enzyme that plays a role in regulating ferroptosis. It is also involved in a wide variety of biological processes, such as tumor cell growth invasion, migration, and resistance to drugs. This study comprehensively examined the role of GPX4 in NSCLC and investigated the clinical feasibility of targeting GPX4 for NSCLC treatment. We discovered that GPX4 influences the progression of NSCLC More >

HENG ZHANG^1,#, XIAO YANG^2,#, YUJIN GUO³, HAIBO ZHAO⁴, PEI JIANG^5,*, QING-QING YU^3,*

Oncology Research, Vol.33, No.4, pp. 837-849, 2025, DOI:10.32604/or.2024.053882 - 19 March 2025

Abstract As living conditions improve and diagnostic capabilities advance, the incidence of tumors has increased, with cancer becoming a leading cause of death worldwide. Surgery, chemotherapy, and radiotherapy are the most common treatments. Despite advances in treatment options, chemotherapy remains a routine first-line treatment for most tumors. Due to the continuous and extensive use of chemotherapy drugs, tumor resistance often develops, becoming a significant cause of treatment failure and poor prognosis. Recent research has increasingly focused on how long stranded non-coding RNAs (LncRNAs) influence the development of malignant tumors and drug resistance by regulating gene expression More >

Sally Negm¹, Badwy Mohdly², Motrih Al-Mutiry³, Wael Shehata⁴, Karima Ahmed⁵, Mohamed Abou-Zeid^2,*, Rana Elessawy⁶, Ashgan Abdel-Azim⁵, Amr Abdel-Fattah², Amani Omar Abuzaid⁷, Enas A. Almanzalawi⁷, Tahani M. Alqahtani⁷, Shouaa A. Alrobaish⁸, Diaa Abd El Moneim⁹, Ahmed M. Abbas^10,11, Mohammed O. Alshaharni¹⁰, Huda Alghamdi¹⁰, Shaimaa G. Salama¹², Kairy Amer⁵

Phyton-International Journal of Experimental Botany, Vol.94, No.2, pp. 347-377, 2025, DOI:10.32604/phyton.2025.057448 - 06 March 2025

Abstract Barley (Hordeum vulgare L.) is a significant global crop that thrives in various climatic and drought-stress conditions. Furthermore, increased drought intervals and more significant weather variability resulting from climate change can affect the severity of plant diseases. Therefore, two primary objectives of integrated disease management regarding climate change are identifying cultivars resistant to foliar diseases and understanding disease progression under abiotic stress. In the current study, we assessed the quantitative foliar disease resistance of 17 commercial barley cultivars under both normal and water stress conditions over two growing seasons (from 2020/21 to 2021/22). The findings demonstrated… More >

Shun Chen^1,2,3, Yingjie Wang¹, Xingyang He^1,2,3,*, Ying Su^1,2,3, Yingyuan Pan¹, Yimin Cao¹, Wentian Wang¹, Chao Yang^1,2,3, Bo Jiang^1,2,3, Shaolin Zhang⁴

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.2, pp. 387-404, 2025, DOI:10.32604/fdmp.2024.055697 - 06 March 2025

Abstract Styrene-butadiene-styrene (SBS) modified asphalt (SA) has long found effective applications in road construction materials. When combined with fillers, SBS-modified asphalt has demonstrated promising resistance to fatigue cracking caused by temperature fluctuations and aging. In this study, molybdenum disulfide (MoS₂) and polyphosphoric acid (PPA) were ground in naphthenic oil (NO) and subjected to mechanical activation to create PPA-modified MoS₂, referred to as OMS-PPA. By blending various ratios of OMS-PPA with SBS-modified asphalt, composite-modified asphalts were successfully developed to enhance their overall properties. To assess the mechanical characteristics and stability of these modified asphalts, various methods were employed,… More > Graphic Abstract

Oncology Research Editorial Office

Oncology Research, Vol.33, No.3, pp. 733-733, 2025, DOI:10.32604/or.2024.056906 - 28 February 2025

Abstract This article has no abstract. More >