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    ARTICLE

    Effects of prenatal stress on male offspring sexual maturity

    NANCY RODRÍGUEZ, NORA MAYER, HÉCTOR F. GAUNA

    BIOCELL, Vol.31, No.1, pp. 67-74, 2007, DOI:10.32604/biocell.2007.31.067

    Abstract Prenatal stimulations have been shown to have long-term effects on at reproductive activity. We evaluated the influence of the prenatal stress on the hypothalamic-pituitary-gonad (HPG) axis in male offsprings from mothers with high number of offsprings per litter (HNL) and low number of offsprings per litter (LNL) after hypothesizing that the number of offsprings per litter may modify the effect of the prenatal stress on the HPG of adult offsprings. Pregnant Wistar rats were used for this study. Immobilization (IMO) stress was used, 30 min, 3 times per week, from the 5th to 21st day… More >

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