Yuan Xu^1,*, Govind Gour², Manuela Galati³, Abdollah Saboori³, Antonio Pellegrino⁴

The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.013220

Abstract The dynamic behaviour of Ti-6Al-2Sn-4Zr-2Mo additively manufactured by electron beam melting (EBM) is presented in this study considering synchronised tension-torsion loading. A bespoke spilt Hopkinson Tension-Torsion bar is used to generate combined tensile and torsional stress pulses that interact simultaneously with a novel specimen geometry. High-speed digital imaging correlation techniques are employed to assess the high-rate deformation and crack propagation of the specimen. The material's dynamic response was analysed across a spectrum of stress states, including uniaxial tension, shear, and combinations of tension and shear at strain rates ranging between 500 s^-1 and 2000 s^-1. Comparable More >

Xueyi Yang¹, Yue Xu¹, Chun Yang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 101-101, 2019, DOI:10.32604/mcb.2019.07117

Abstract Cell-matrix interactions guide various cell behaviors, including proliferation, differentiation, migration, etc. Integrins, as a known transmembrane mechanosensor, undergo conformational changes in response to mechanical stimuli, and manipulate cell-matrix chemical-mechanical coupled signaling transduction [1]. The integrin-ligand bond kinetics has gain increasing attention among researchers. Independent studies showed that the integrin-ligand bond has been reported to be reinforced by the applied force f, while the loading rate df/dt had little effect on the bond lifetime [2].
We previously observed a dramatic increase in bond lifetime beyond a loading rate threshold for the integrin α2β1-DGEA bond, by introducing… More >