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Search Results (7)
  • Open Access

    ARTICLE

    Effectiveness of Post-Traumatic Growth Intervention to Promote Positive PostTraumatic Traits in Chinese Breast Cancer Patients: A Randomized Controlled Trial

    Cuirong Xu1,*, Han Yan2, Dawei Xu3, Guanjie Chen5, Qian Xu2, Kunpeng Li6, Yehao Rui7, Zanmin Song3, Neeraj Gill3, Jing Sun3,4,*

    International Journal of Mental Health Promotion, Vol.25, No.10, pp. 1089-1102, 2023, DOI:10.32604/ijmhp.2023.030526 - 03 November 2023

    Abstract Objective: The purpose of this study was to evaluate the effectiveness of post-traumatic growth (PTG) model-based intervention to improve positive psychological traits in Chinese breast cancer patients. Design: A randomized control trial of a psychological group intervention based on PTG model. Methods: The Clinical Trial was registered on 17 August 2019 at Chinese Clinical Trials.gov with Registration number ChiCTR1900025264. A total of 92 patients with breast cancer were recruited. The participants were randomly assigned to the experimental group (n = 46) and the control group (n = 46). A six-session psychological group intervention based on PTG model… More >

  • Open Access

    ARTICLE

    Short-Term Mindfulness Intervention on Adolescents’ Negative Emotion under Global Pandemic

    Yue Yuan1,*, Aibao Zhou1,*, Tinghao Tang1, Manying Kang2, Haiyan Zhao1, Zhi Wang3

    International Journal of Mental Health Promotion, Vol.25, No.4, pp. 563-577, 2023, DOI:10.32604/ijmhp.2023.022161 - 01 March 2023

    Abstract Objective: In this research, we tried to explore how short-term mindfulness (STM) intervention affects adolescents’ anxiety, depression, and negative and positive emotion during the COVID-19 pandemic. Design: 10 classes were divided into experiment groups (5 classes; n = 238) and control (5 classes; n = 244) randomly. Hospital Anxiety and Depression Scale (HADS) and Positive and Negative Affect Schedule (PANAS) were used to measure participants’ dependent variables. In the experiment group, we conducted STM practice interventions every morning in their first class from March to November 2020. No interventions were conducted in the control group. Methods: Paired-sample t-tests were used to identify… More >

  • Open Access

    ARTICLE

    Mindfulness Intervention on Adolescents’ Emotional Intelligence and Psychological Capital during the COVID-19 Pandemic: A Randomized Controlled Trial

    Aibao Zhou1, Yue Yuan1,*, Manying Kang2

    International Journal of Mental Health Promotion, Vol.24, No.5, pp. 665-677, 2022, DOI:10.32604/ijmhp.2022.019623 - 27 July 2022

    Abstract Background: Since the outbreak of COVID-19 caused adults suffer from mental disorders, it would be an essential for psychologist to help individuals overcome mental disorders. Objective: This study aim to explore whether the intervention of mindfulness is an efficient method to enhance adolescents’ emotional intelligence (EI) and psychological capital (PC) to provide a theoretical basis and future directions for both targeted crisis intervention and psychological trauma recovery plans. Design: This research was designed as randomized controlled trial and total of 798 students were evaluated statistically. Methods: We used paired-sample t-tests and repeated measures ANOVA to compare every factor defined… More >

  • Open Access

    ARTICLE

    Endostar, an Antiangiogenesis Inhibitor, Combined With Chemoradiotherapy for Locally Advanced Cervical Cancer

    Heming Lu*†1, Yuying Wu‡1, Xu Liu, Huixian Huang, Hailan Jiang, Chaohua Zhu, Yuping Man§, Zhaohong Chen, Xianfeng Long, Qiang Pang, Luxing Peng, Xianglong Li, Junzhao Gu, Shan Deng, Ligang Xing*

    Oncology Research, Vol.28, No.9, pp. 929-944, 2020, DOI:10.3727/096504021X16318716607908

    Abstract This phase II randomized clinical trial aimed to assess the efficacy and toxicity of Endostar, an antiangiogenesis inhibitor, combined with concurrent chemoradiotherapy (CCRT) for locally advanced cervical cancer (LACC). Patients with LACC were randomly assigned to either CCRT plus Endostar (CCRT+E arm) or CCRT alone (CCRT arm). All patients received pelvic intensity-modulated radiation therapy (IMRT) and brachytherapy. Weekly cisplatin was administered concurrently with IMRT. Patients in the CCRT+E arm also received concurrent Endostar every 3 weeks for two cycles. The primary endpoint was progression-free survival (PFS) and acute toxicities. The exploratory endpoint was the impact… More >

  • Open Access

    ARTICLE

    Excellent Early Outcomes of Combined Chemotherapy With Arsenic Trioxide for Stage 4/M Neuroblastoma in Children: A Multicenter Nonrandomized Controlled Trial

    Chunmou Li*1, Xiaomin Peng*1, Chuchu Feng*1, Xilin Xiong*, Jianxin Li, Ning Liao, Zhen Yang§, Aiguo Liu, Pingping Wu*, Xuehong Liang, Yunyan He, Xin Tian§, Yunbi Lin§, Songmi Wang, Yang Li*

    Oncology Research, Vol.28, No.7-8, pp. 791-800, 2020, DOI:10.3727/096504021X16184815905096

    Abstract This nonrandomized, multicenter cohort, open-label clinical trial evaluated the efficacy and safety of combined chemotherapy with arsenic trioxide (ATO) in children with stage 4/M neuroblastoma (NB). We enrolled patients who were newly diagnosed with NB and assessed as stage 4/M and received either traditional chemotherapy or ATO combined with chemotherapy according to their own wishes. Twenty-two patients were enrolled in the trial group (ATO combined with chemotherapy), and 13 patients were enrolled in the control group (traditional chemotherapy). Objective response rate (ORR) at 4 weeks after completing induction chemotherapy was defined as the main outcome,… More >

  • Open Access

    ARTICLE

    Comparative Effectiveness of Mind-Body Exercise Versus Cognitive Behavioral Therapy for College Students with Problematic Smartphone Use: A Randomized Controlled Trial

    Chunping Lu1,#, Liye Zou2,#, Benjamin Becker3, Mark D. Griffiths4, Qian Yu2, Si-Tong Chen5, Zsolt Demetrovics6, Can Jiao7, Xinli Chi7, Aiguo Chen8, Albert Yeung9, Shijie Liu10, Yanjie Zhang2,11,*

    International Journal of Mental Health Promotion, Vol.22, No.4, pp. 271-282, 2020, DOI:10.32604/IJMHP.2020.014419 - 22 December 2020

    Abstract Purpose: The purpose of the present study was to compare the effectiveness of mind-body exercise (ME) and cognitive behavioral therapy (CBT) on addiction level and psychological well-being among college students with problematic smartphone use (PSU). Methods: A 12-week randomized controlled study was carried out at a university in central China. A total of 95 PSU college students who met the inclusion criteria were randomly assigned to a ME group (ME, n = 31), CBT group (CBT, n = 30), or control group (CG, n = 34). Both ME intervention and CBT, twice per week for 90… More >

  • Open Access

    ARTICLE

    Clinical Value of Capecitabine-Based Combination Adjuvant Chemotherapy in Early Breast Cancer: A Meta-Analysis of Randomized Controlled Trials

    Guanling Chen1, Zhaoze Guo1, Minfeng Liu, Guangyu Yao, Jianyu Dong, Jingyun Guo, Changsheng Ye

    Oncology Research, Vol.25, No.9, pp. 1567-1578, 2017, DOI:10.3727/096504017X14897173032733

    Abstract Capecitabine has consistently demonstrated high efficacy and acceptable tolerability in salvage chemotherapy for advanced breast cancer. However, there remains no consensus on its role in adjuvant chemotherapy for early breast cancer (EBC). To estimate the value of capecitabine-based combination adjuvant treatment in EBC, eight randomized controlled trials with 14,072 participants were analyzed. The efficacy and safety outcomes included disease-free survival (DFS), overall survival (OS), relapse, breast cancer-specific survival (BCSS), and grades 3–5 adverse events. Capecitabine-based combination adjuvant chemotherapy demonstrated a 16% increase in BCSS (HR = 0.84, 95% CI = 0.71–0.98, p = 0.03) in the… More >

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