Shivani M. Bhatt1,*, Michael L. O’Byrne2, Michael McBride2, Stephen M. Paridon2, Elizabeth Goldmuntz2, Laura Mercer-Rosa2
Congenital Heart Disease, Vol.15, No.2, pp. 101-115, 2020, DOI:10.32604/CHD.2020.011287
- 23 June 2020
Abstract Objective: The determinants of exercise capacity in repaired tetralogy of
Fallot (rTOF) are multifactorial and remain incompletely understood. This study
sought to evaluate the association of chronotropic response with exercise parameters
and investigate the determinants of heart rate reserve (HRR) in a cohort of children
and adolescents with rTOF. Design: We retrospectively analyzed patients with
rTOF, age 8–18 years, who underwent cardiac magnetic resonance (CMR) and
cardiopulmonary exercise test (CPET) for research purposes. Linear regression
models were performed to test associations among clinical, CMR and CPET
parameters. Outcomes included percent-predicted maximum VO2 (%mVO2) and
HRR. Results: A total… More >