Xiaoli Zhang^1,2,#, Xiaohong Yin^2,3,#, Jiana Chen^3,#, Fangbo Cao³, Yu Liu³, Zhengwu Xiao³, Liqin Hu³, Guanghui Chen³, Tianfeng Liang^1,2,*, Min Huang^3,*

Phyton-International Journal of Experimental Botany, Vol.90, No.4, pp. 1285-1292, 2021, DOI:10.32604/phyton.2021.014778 - 27 April 2021

Abstract Protein in rice grains is an important source of nutrition for rice consumers. This study mainly aimed to identify the critical factors that determine grain protein concentration in rice. Accumulation parameters, including mean accumulation rate (R_mean) and active accumulation duration (D_active), for protein and non-protein components and their correlations with protein concentration in rice grains were investigated in field experiments conducted over two years with six rice cultivars. Results showed that grain protein concentration ranged from 9.6% to 11.9% across cultivars and years. Accumulation processes of protein and non-protein components were well fitted by the logistic More >

Fei Liu^*1, Bihua Lin^*1, Xin Liu^*, Wenzhang Zhang^*, Erying Zhang^*, Liang Hu^*, Yuefan Ma^*, Xiangyong Li^*, Xudong Tang^*†

Oncology Research, Vol.23, No.3, pp. 109-118, 2015, DOI:10.3727/096504015X14496932933610

Abstract Extracellular signal-regulated kinase (ERK)1/2 signaling pathway plays a critical role in regulating tumor angiogenesis. Our previous studies have demonstrated that HPV-16 oncoproteins enhanced hypoxia-inducible factor-1α (HIF-1α) protein accumulation and vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) expression in non-small cell lung cancer (NSCLC) cells, thus contributing to angiogenesis. In this study, we further investigated the role of ERK1/2 signaling pathway in HPV-16 oncoprotein-induced HIF-1α, VEGF, and IL-8 expression and in vitro angiogenesis in NSCLC cells. Our results showed that HPV-16 E6 and HPV-16 E7 oncoproteins promoted the activation of ERK1/2 signaling pathway in A549 More >