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  • Open Access

    REVIEW

    Evolution and Prospects of Foundation Models: From Large Language Models to Large Multimodal Models

    Zheyi Chen1,, Liuchang Xu1,, Hongting Zheng1, Luyao Chen1, Amr Tolba2,3, Liang Zhao4, Keping Yu5,*, Hailin Feng1,*

    CMC-Computers, Materials & Continua, Vol.80, No.2, pp. 1753-1808, 2024, DOI:10.32604/cmc.2024.052618

    Abstract Since the 1950s, when the Turing Test was introduced, there has been notable progress in machine language intelligence. Language modeling, crucial for AI development, has evolved from statistical to neural models over the last two decades. Recently, transformer-based Pre-trained Language Models (PLM) have excelled in Natural Language Processing (NLP) tasks by leveraging large-scale training corpora. Increasing the scale of these models enhances performance significantly, introducing abilities like context learning that smaller models lack. The advancement in Large Language Models, exemplified by the development of ChatGPT, has made significant impacts both academically and industrially, capturing widespread… More >

  • Open Access

    ARTICLE

    IMPACT de la déprivation sociale sur les difficultés psychosociales au décours d’un cancer pédiatrique : une étude prospective

    Fanny Delehaye1,2,*, Olivier Dejardin1,3, Isabelle Pellier4, Ludivine Launay1,5, Maxime Esvan6, Damien Bodet2, Liana Carausu7, Julien Lejeune8, Frédéric Millot9, Caroline Thomas10, Virginie Gandemer11, Arnaud Alves1,12, Julien Rod1,13

    Psycho-Oncologie, Vol.18, No.2, pp. 117-126, 2024, DOI:10.32604/po.2024.043073

    Abstract La période post-traitement une part fondamental de la prise en charge du cancer pédiatrique. Durant cette période, les difficultés scolaires et psychologiques chez les survivants d’un cancer pédiatriques (SCP) sont connues et peuvent être pronostic sur la bonne réintégration sociale. Cette étude estime l’influence de la déprivation sociale du foyer de l’enfant sur ces difficultés. Notre étude se base sur une base de données multicentrique, et se concentre sur les SCP avant reçu une évaluation psychosociale au cours de leur suivi, de 2013 à 2020. Nous rapportons les données des difficultés scolaires et psychologiques. Le… More >

  • Open Access

    EDITORIAL

    Key Issues for Modelling, Operation, Management and Diagnosis of Lithium Batteries: Current States and Prospects

    Bo Yang1,*, Yucun Qian1, Jianzhong Xu2, Yaxing Ren3, Yixuan Chen4

    Energy Engineering, Vol.121, No.8, pp. 2085-2091, 2024, DOI:10.32604/ee.2024.050083

    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    Research Progress on Plant Anti-Freeze Proteins

    Zhengyang Zhang#, Weixue Liu#, Yinran Huang*, Ping Li*

    Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1263-1274, 2024, DOI:10.32604/phyton.2024.050755

    Abstract Plant antifreeze proteins (AFPs) are special proteins that can protect plant cells from ice crystal damage in low-temperature environments, and they play a crucial role in the process of plants adapting to cold environments. Proteins with these characteristics have been found in fish living in cold regions, as well as many plants and insects. Although research on plant AFPs started relatively late, their application prospects are broad, leading to the attention of many researchers to the isolation, cloning, and genetic improvement of plant AFP genes. Studies have found that the distribution of AFPs in different species… More >

  • Open Access

    ARTICLE

    Prospect Theory Based Individual Irrationality Modelling and Behavior Inducement in Pandemic Control

    Wenxiang Dong, H. Vicky Zhao*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 139-170, 2024, DOI:10.32604/cmes.2024.047156

    Abstract Understanding and modeling individuals’ behaviors during epidemics is crucial for effective epidemic control. However, existing research ignores the impact of users’ irrationality on decision-making in the epidemic. Meanwhile, existing disease control methods often assume users’ full compliance with measures like mandatory isolation, which does not align with the actual situation. To address these issues, this paper proposes a prospect theory-based framework to model users’ decision-making process in epidemics and analyzes how irrationality affects individuals’ behaviors and epidemic dynamics. According to the analysis results, irrationality tends to prompt conservative behaviors when the infection risk is low More >

  • Open Access

    REVIEW

    Survey and Prospect for Applying Knowledge Graph in Enterprise Risk Management

    Pengjun Li1, Qixin Zhao1, Yingmin Liu1, Chao Zhong1, Jinlong Wang1,*, Zhihan Lyu2

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3825-3865, 2024, DOI:10.32604/cmc.2024.046851

    Abstract Enterprise risk management holds significant importance in fostering sustainable growth of businesses and in serving as a critical element for regulatory bodies to uphold market order. Amidst the challenges posed by intricate and unpredictable risk factors, knowledge graph technology is effectively driving risk management, leveraging its ability to associate and infer knowledge from diverse sources. This review aims to comprehensively summarize the construction techniques of enterprise risk knowledge graphs and their prominent applications across various business scenarios. Firstly, employing bibliometric methods, the aim is to uncover the developmental trends and current research hotspots within the… More >

  • Open Access

    REVIEW

    MicroRNAs modulation in lung cancer: exploring dual mechanisms and clinical prospects

    SHAHID HUSSAIN1,*, HABIB BOKHARI1, XINGXING FAN2, SHAUKAT IQBAL MALIK3, SUNDAS IJAZ1, MUHAMMAD ADNAN SHEREEN4, AIMAN FATIMA3

    BIOCELL, Vol.48, No.3, pp. 403-413, 2024, DOI:10.32604/biocell.2024.044801

    Abstract The global incidence of lung cancer is marked by a considerably elevated mortality rate. MicroRNAs (miRNAs) exert pivotal influence in the intricate orchestration of gene regulation, and their dysregulation can precipitate dire consequences, notably cancer. Within this context, miRNAs encapsulated in exosomes manifest a diversified impact on the landscape of lung cancer, wherein their actions may either foster angiogenesis, cell proliferation, and metastasis, or counteract these processes. This comprehensive review article discerns potential targets for the prospective development of therapeutic agents tailored for lung cancer. Tumor-suppressive miRNAs, such as miR-204, miR-192, miR-30a, miR-34a, miR-34b, miR-203,… More >

  • Open Access

    ARTICLE

    Optical Neural Networks: Analysis and Prospects for 5G Applications

    Doaa Sami Khafaga1, Zongming Lv2, Imran Khan3,4, Shebnam M. Sefat5, Amel Ali Alhussan1,*

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3723-3740, 2023, DOI:10.32604/cmc.2023.039956

    Abstract With the capacities of self-learning, acquainted capacities, high-speed looking for ideal arrangements, solid nonlinear fitting, and mapping self-assertively complex nonlinear relations, neural systems have made incredible advances and accomplished broad application over the final half-century. As one of the foremost conspicuous methods for fake insights, neural systems are growing toward high computational speed and moo control utilization. Due to the inborn impediments of electronic gadgets, it may be troublesome for electronic-implemented neural systems to make the strides these two exhibitions encourage. Optical neural systems can combine optoelectronic procedures and neural organization models to provide ways… More >

  • Open Access

    ARTICLE

    Research progress and prospects of nucleic acid isothermal amplification technology

    SHUHUI WU1,2,#, PING XU3,#, XIANGBIN XU2, SONG-BAI LIU1,2,*

    BIOCELL, Vol.47, No.11, pp. 2385-2395, 2023, DOI:10.32604/biocell.2023.029687

    Abstract Nucleic acid (DNA and RNA) detection and quantification methods play vital roles in molecular biology. With the development of molecular biology, isothermal amplification of DNA/RNA, as a new molecular biology technology, can be amplified under isothermal condition, it has the advantages of high sensitivity, high specificity, and high efficiency, and has been applied in various fields of biotechnology, including disease diagnosis, pathogen detection, food hygiene and safety detection and so on. This paper introduces the progress of isothermal amplification technology, including rolling circle amplification (RCA), nucleic acid sequence-dependent amplification (NASBA), strand displacement amplification (SDA), loop-mediated More >

  • Open Access

    REVIEW

    Cancer-associated fibroblasts of colorectal cancer: Translational prospects in liquid biopsy and targeted therapy

    ELYN AMIELA SALLEH1, YEONG YEH LEE2, ANDEE DZULKARNAEN ZAKARIA3, NUR ASYILLA CHE JALIL4, MARAHAINI MUSA1,*

    BIOCELL, Vol.47, No.10, pp. 2233-2244, 2023, DOI:10.32604/biocell.2023.030541

    Abstract Colorectal cancer (CRC) is a major global health concern. Accumulation of cancer-associated fibroblasts (CAFs) in CRC is associated with poor prognosis and disease recurrence. CAFs are the main cellular component of the tumor microenvironment. CAF-tumor cell interplay, which is facilitated by various secretomes, drives colorectal carcinogenesis. The complexity of CAF populations contributes to the heterogeneity of CRC and influences patient survival and treatment response. Due to their significant roles in colorectal carcinogenesis, different clinical applications utilizing or targeting CAFs have been suggested. Circulating CAFs (cCAFs) which can be detected in blood samples, have been proposed… More > Graphic Abstract

    Cancer-associated fibroblasts of colorectal cancer: Translational prospects in liquid biopsy and targeted therapy

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