JOSé A. BOGA^1,2, ANA COTO-MONTES^2,3,*, RUSSEL J. REITER⁴

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.068245 - 23 January 2026

Abstract Aerobic glycolysis, also known as the Warburg effect, and the accumulation of lactate that it causes, are increasingly recognized outside the field of oncology as triggers of chronic non-neoplastic disorders. This review integrates preclinical and clinical evidence to evaluate the ability of melatonin to reverse Warburg-effect-like metabolic reprogramming. Literature on neurodegeneration, age-related sarcopenia, type 2 diabetes, chronic kidney disease, heart failure and pulmonary arterial hypertension (PAH) has been reviewed and synthesised. In all of these conditions, hypoxia-inducible factor 1α (HIF-1α) and pyruvate dehydrogenase kinase 4 (PDK4) inhibit the pyruvate dehydrogenase complex. This diverts pyruvate away… More >

Williams Kyei^*, Chunyong Yin, Kelvin Amos Nicodemas, Khagendra Darlami

Journal on Artificial Intelligence, Vol.8, pp. 19-38, 2026, DOI:10.32604/jai.2026.074988 - 20 January 2026

Abstract The COVID-19 pandemic has underscored the need for rapid and accurate diagnostic tools to differentiate respiratory infections from normal cases using chest X-rays (CXRs). Manual interpretation of CXRs is time-consuming and prone to errors, particularly in distinguishing COVID-19 from viral pneumonia. This research addresses these challenges by proposing a customized EfficientNet-B0 model for ternary classification (COVID-19, Viral Pneumonia, Normal) on the COVID-19 Radiography Database. Employing transfer learning with architectural modifications, including a tailored classification head and regularization techniques, the model achieves superior performance. Evaluated via accuracy, F1-score (macro-averaged), AUROC (macro-averaged), precision (macro-averaged), recall (macro-averaged), inference… More >

Tai Liu^1,2, Mao Ye^2,*, Feng Wu³, Chao Zhu², Bo Chen², Guoyan Zhang^1,*

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072692 - 12 January 2026

Abstract With the continuous advancement of unmanned technology in various application domains, the development and deployment of blind-spot-free panoramic video systems have gained increasing importance. Such systems are particularly critical in battlefield environments, where advanced panoramic video processing and wireless communication technologies are essential to enable remote control and autonomous operation of unmanned ground vehicles (UGVs). However, conventional video surveillance systems suffer from several limitations, including limited field of view, high processing latency, low reliability, excessive resource consumption, and significant transmission delays. These shortcomings impede the widespread adoption of UGVs in battlefield settings. To overcome these… More >

Shuangqing Song¹, Yuan Chen², Xuguang Hu¹, Juwei Zhang^1,3,*

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072392 - 12 January 2026

Abstract In multi-domain neural machine translation tasks, the disparity in data distribution between domains poses significant challenges in distinguishing domain features and sharing parameters across domains. This paper proposes a Transformer-based multi-domain-aware mixture of experts model. To address the problem of domain feature differentiation, a mixture of experts (MoE) is introduced into attention to enhance the domain perception ability of the model, thereby improving the domain feature differentiation. To address the trade-off between domain feature distinction and cross-domain parameter sharing, we propose a domain-aware mixture of experts (DMoE). A domain-aware gating mechanism is introduced within the… More >

Zixuan Guo¹, Houbin Wang², Sameer Kumar^1,*, Yuanfang Chen³

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072064 - 12 January 2026

Abstract With the rapid development of digital culture, a large number of cultural texts are presented in the form of digital and network. These texts have significant characteristics such as sparsity, real-time and non-standard expression, which bring serious challenges to traditional classification methods. In order to cope with the above problems, this paper proposes a new ASSC (ALBERT, SVD, Self-Attention and Cross-Entropy)-TextRCNN digital cultural text classification model. Based on the framework of TextRCNN, the Albert pre-training language model is introduced to improve the depth and accuracy of semantic embedding. Combined with the dual attention mechanism, the… More >

Hongcheng Zhao¹, Tong Yang ², Yihui Hu², Fengxiang Guo^2,*

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.068987 - 08 January 2026

Abstract With the rapid development of transportation infrastructure, ensuring road safety through timely and accurate highway inspection has become increasingly critical. Traditional manual inspection methods are not only time-consuming and labor-intensive, but they also struggle to provide consistent, high-precision detection and real-time monitoring of pavement surface defects. To overcome these limitations, we propose an Automatic Recognition of Pavement Defect (ARPD) algorithm, which leverages unmanned aerial vehicle (UAV)-based aerial imagery to automate the inspection process. The ARPD framework incorporates a backbone network based on the Selective State Space Model (S³M), which is designed to capture long-range temporal dependencies.… More >

Himadri Nath Saha¹, Dipanwita Chakraborty Bhattacharya^2,*, Sancharita Dutta³, Arnab Bera³, Srutorshi Basuray⁴, Satyasaran Changdar⁵, Saptarshi Banerjee⁶, Jon Turdiev⁷

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-56, 2026, DOI:10.32604/cmc.2025.070507 - 09 December 2025

Abstract The emergence of Medical Large Language Models has significantly transformed healthcare. Medical Large Language Models (Med-LLMs) serve as transformative tools that enhance clinical practice through applications in decision support, documentation, and diagnostics. This evaluation examines the performance of leading Med-LLMs, including GPT-4Med, Med-PaLM, MEDITRON, PubMedGPT, and MedAlpaca, across diverse medical datasets. It provides graphical comparisons of their effectiveness in distinct healthcare domains. The study introduces a domain-specific categorization system that aligns these models with optimal applications in clinical decision-making, documentation, drug discovery, research, patient interaction, and public health. The paper addresses deployment challenges of Medical-LLMs, More >

Cyreneo Dofitas¹, Yong-Woon Kim², Yung-Cheol Byun^3,*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-19, 2026, DOI:10.32604/cmc.2025.069374 - 09 December 2025

Abstract Recent advances in deep learning have significantly improved flood detection and segmentation from aerial and satellite imagery. However, conventional convolutional neural networks (CNNs) often struggle in complex flood scenarios involving reflections, occlusions, or indistinct boundaries due to limited contextual modeling. To address these challenges, we propose a hybrid flood segmentation framework that integrates a Vision Transformer (ViT) encoder with a U-Net decoder, enhanced by a novel Flood-Aware Refinement Block (FARB). The FARB module improves boundary delineation and suppresses noise by combining residual smoothing with spatial-channel attention mechanisms. We evaluate our model on a UAV-acquired flood More >

Illia Khurtin^*, Mukesh Prasad

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-15, 2026, DOI:10.32604/cmc.2025.067481 - 09 December 2025

Abstract The field of artificial intelligence has advanced significantly in recent years, but achieving a human-like or Artificial General Intelligence (AGI) remains a theoretical challenge. One hypothesis suggests that a key issue is the formalisation of extracting meaning from information. Meaning emerges through a three-stage interpretative process, where the spectrum of possible interpretations is collapsed into a singular outcome by a particular context. However, this approach currently lacks practical grounding. In this research, we developed a model based on contexts, which applies interpretation principles to the visual information to address this gap. The field of computer… More >

Ali S. Alzaharani, Abid Iqbal^*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-27, 2026, DOI:10.32604/cmc.2025.070410 - 10 November 2025

Abstract In this study, an automated multimodal system for detecting, classifying, and dating fruit was developed using a two-stage YOLOv11 pipeline. In the first stage, the YOLOv11 detection model locates individual date fruits in real time by drawing bounding boxes around them. These bounding boxes are subsequently passed to a YOLOv11 classification model, which analyzes cropped images and assigns class labels. An additional counting module automatically tallies the detected fruits, offering a near-instantaneous estimation of quantity. The experimental results suggest high precision and recall for detection, high classification accuracy (across 15 classes), and near-perfect counting in More >