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  • Open Access

    PROCEEDINGS

    Non-Newtonian Rheology of Cell Suspension in a Porous Scaffold During Perfusion Cell Seeding

    Ziying Zhang1,*, Chu Li1, Junwei Zhu1, Qinghong Wu1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.010912

    Abstract The process of perfusion seeding of cells into a porous scaffold represents a pivotal initial stage in the development of tissue-engineered bones. The rheological behavior of the cell suspension plays a crucial role in influencing the transport and distribution of cells within the scaffold. Currently, there is limited understanding of the non-Newtonian rheology of cell suspensions in complex pores which differs significantly from simple channels or linear shear flow. In this study, we utilize our previously developed mesoscopic model of perfusion cell seeding to investigate the rheological behavior of cell suspensions at the cellular scale. More >

  • Open Access

    PROCEEDINGS

    Treatments of Fractures Intersection in the Enriched-Embedded Discrete Fracture Model (nEDFM) for Porous Flow

    Kaituo Jiao1, Dongxu Han2,*, Bo Yu2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.1, pp. 1-3, 2024, DOI:10.32604/icces.2024.011520

    Abstract Motivated by the fractures being very thin compared to the size of rock matrix, utilizing the non-conforming grid is an efficient approach to simulate fluid flow in fractured porous media. The embedded discrete fracture model (EDFM) is the typical one that using the conforming grid and modelled based on the finite volume method (FVM) framework. The EDFM maintains advantages of mass conservation and low computational complexity, but it cannot characterize blocking fractures and has a low accuracy on the mass exchange between fractures and matrix [1]. In our previous work [2], we developed the enriched-EDFM… More >

  • Open Access

    ABSTRACT

    A Multigrid Coupled DEIM Method for High-Efficient Simulation of Compressible Gas Porous Flow

    Jingfa Li1, Daobing Wang1, Bo Yu1,*, Shuyu Sun2, Dongliang Sun1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.23, No.1, pp. 3-3, 2021, DOI:10.32604/icces.2021.08209

    Abstract In natural gas engineering, the numerical simulation plays a significant role in the exploration, production and optimization of natural gas reservoir. However, numerical simulations of compressible gas flow in porous media are always expensive due to the gas compressibility and nonlinear properties. To save the computational cost, in this work we present a multigrid coupled discrete empirical interpolation method (MG-DEIM) to speedup the simulation of compressible gas porous flow. In this MG-DEIM framework, the core idea is that the multigrid method based on the full approximate scheme (FAS) is used to solve the flow equation… More >

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