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  • Open Access

    ARTICLE

    Generalized Anxiety Disorder Prevalence and Related Risk Factors among Females with Polycystic Ovarian Syndrome in Jazan Region, Saudi Arabia

    Abdullah A. Alharbi1, Ahmad Y. Alqassim1,*, Mohammad A. Jareebi1, Ahmad A. Alharbi2, Nada M. Makein1, Fatimah H. Al Ghazwi3, Seba Y. Muzaiiadi3, Joud N. Refaei3, Revan A. Arishi3, Bashaer A. Al Rajhi3, Fatima A. Aqili3, Saleha M. Ayoub3, Mohammed A. Muaddi1

    International Journal of Mental Health Promotion, Vol.27, No.5, pp. 701-716, 2025, DOI:10.32604/ijmhp.2025.062924 - 05 June 2025

    Abstract Background: Polycystic ovarian syndrome (PCOS), a common endocrine disorder in reproductive-aged women, has substantial physical and psychological impacts. While the physical manifestations of PCOS are well established, the psychological burden, especially anxiety, is understudied in Saudi Arabia. This study aimed to assess the prevalence of generalized anxiety disorder among females with PCOS compared to those without PCOS, and to identify the clinical and sociodemographic factors associated with anxiety in the Jazan region of Saudi Arabia. Methods: A cross-sectional study was conducted between January and March 2023 using an Arabic self-administered online questionnaire distributed via social… More >

  • Open Access

    ARTICLE

    Automatic Diagnosis of Polycystic Ovarian Syndrome Using Wrapper Methodology with Deep Learning Techniques

    Mohamed Abouhawwash1,2, S. Sridevi3, Suma Christal Mary Sundararajan4, Rohit Pachlor5, Faten Khalid Karim6, Doaa Sami Khafaga6,*

    Computer Systems Science and Engineering, Vol.47, No.1, pp. 239-253, 2023, DOI:10.32604/csse.2023.037812 - 26 May 2023

    Abstract One of the significant health issues affecting women that impacts their fertility and results in serious health concerns is Polycystic ovarian syndrome (PCOS). Consequently, timely screening of polycystic ovarian syndrome can help in the process of recovery. Finding a method to aid doctors in this procedure was crucial due to the difficulties in detecting this condition. This research aimed to determine whether it is possible to optimize the detection of PCOS utilizing Deep Learning algorithms and methodologies. Additionally, feature selection methods that produce the most important subset of features can speed up calculation and enhance… More >

  • Open Access

    ARTICLE

    Intrauterine high androgen promotes obesity of the offspring of rats with polycystic ovarian syndrome via activating macrophage-angiogenesis-related androgen signaling

    MIN CHEN1,#, YUAN HUANG2,#, WEN XU2, CHUNLIN SU2,*

    BIOCELL, Vol.46, No.6, pp. 1505-1519, 2022, DOI:10.32604/biocell.2022.016564 - 07 February 2022

    Abstract The development of polycystic ovary syndrome (PCOS) is closely related to the chronic inflammatory and obese. Recent studies have found macrophages regulate the chronic inflammation and adipose tissue remodelling, but the underlying mechanisms have not been clarified. In this study, we established a model of PCOS in the offspring rats by high androgen exposure during late pregnancy in parental and established a female rat macrophage eliminating model by rejection of clodronate liposome. Then, the offspring rat macrophage phenotype in offspring female rat adipose tissue, and levels of testosterone, angiogenic factors (PDGF and VEGF) and inflammatory… More >

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