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  • Open Access

    ARTICLE

    Improved Corrosion Resistance of Carbon Reinforced Aluminium Laminates in Atmospheric Environment: Role of Environment Friendly Jute Fibre/ Alumina nano Coating

    M. VASUMATHI1,a,*, VELA MURALI2,b, S. RASHIA BEGUM1,c, N. RAJENDRAN2,d

    Journal of Polymer Materials, Vol.36, No.1, pp. 1-11, 2019, DOI:10.32381/JPM.2019.36.01.1

    Abstract In the Fibre Metal Laminate (FML), Carbon Reinforced Aluminium laminate (CARALL), aluminium is placed next to carbon fibres. The potential difference between the aluminium and carbon is larger, leads to galvanic corrosion, which tries to bring down the durability of the FML. To bring down the effect of corrosion, a material layer is introduced between fibres and aluminium so as to separate them thus lowering the possibility of occurrence of corrosion. Another approach is to coat the surfaces of aluminium with different proportions of aluminium oxide nano particles prior to fabrication of the FML. For both the cases, corrosion rates… More >

  • Open Access

    ARTICLE

    Mathematical Modelling and Simulations of Active Direct Methanol Fuel Cell

    RABIRANJAN MURMUa,b, DEBASHIS ROYa, HAREKRUSHNA SUTARb

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 125-139, 2023, DOI:10.32381/JPM.2023.40.3-4.1

    Abstract A one dimensional isothermal model is proposed by modelling the kinetics of methanol transport at anode flow channel (AFC), membrane and cathode catalyst layer of direct methanol fuel cell (DMFC). Analytical model is proposed to predict methanol cross-over rate through the electrolyte membrane and cell performance. The model presented in this paper considered methanol diffusion and electrochemical oxidation at the anode and cathode channels. The analytical solution of the proposed model was simulated in a MATLAB environment to obtain the polarization curve and leakage current. The effect of methanol concentration on cell voltage and leakage current is studied. The methanol… More >

  • Open Access

    ARTICLE

    CMTM6 deletion affects chemoresistance and macrophage M2 polarization in colorectal cancer cells

    YANG XU1,#, HONGYUN LI1,#, GE YOU2,*

    BIOCELL, Vol.48, No.2, pp. 229-237, 2024, DOI:10.32604/biocell.2023.045030

    Abstract Background: Colorectal cancer (CRC) constitutes the leading cause of death worldwide. Chemoresistance and tumor immune evasion are critical contributors to therapeutic failure in cancer patients. CKLF-like MARVEL transmembrane domain-containing 6 (CMTM6) is aberrantly expressed in various cancers and can regulate tumor immunity. However, its role in chemoresistance and tumor immunity of CRC is not well understood. Methods: Online bioinformatics tools were used to analyze expression and prognosis of CMTM6 in CRC patients. CRC cells were transfected with si-CMTM6. Subsequently, the effects on CRC cell viability and chemoresistance were investigated by CCK-8 assay and flow cytometer. Furthermore, CRC cell-induced macrophage recruitments… More > Graphic Abstract

    CMTM6 deletion affects chemoresistance and macrophage M2 polarization in colorectal cancer cells

  • Open Access

    REVIEW

    Application of exosomal miRNA mediated macrophage polarization in colorectal cancer: Current progress and challenges

    YUN ZHANG1,2,#, SHALING TANG1,2,#, YUBO GAO1,2, ZHONGTING LU1,2, YUAN YANG1,2, JING CHEN3, TAO LI4,*

    Oncology Research, Vol.32, No.1, pp. 61-71, 2024, DOI:10.32604/or.2023.043481

    Abstract Colorectal cancer (CRC) is a major global health problem with high morbidity and mortality rates. Surgical resection is the main treatment for early-stage CRC, but detecting it early is challenging. Therefore, effective therapeutic targets for advanced patients are still lacking. Exosomes, tiny vesicles in body fluids, play a crucial role in tumor metastasis, immune regulation, and drug resistance. Interestingly, they can even serve as a biomarker for cancer diagnosis and prognosis. Studies have shown that exosomes can carry miRNA, mediate the polarization of M1/M2 macrophages, promote the proliferation and metastasis of cancer cells, and affect the prognosis of CRC. Since… More > Graphic Abstract

    Application of exosomal miRNA mediated macrophage polarization in colorectal cancer: Current progress and challenges

  • Open Access

    PROCEEDINGS

    Phase Field Modeling of Coupling Evolution of Polarization, Fracture and Dielectric Breakdown in Ferroelectric Materials

    Yong Zhang1,*, Jie Wang2,3

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.1, pp. 1-1, 2023, DOI:10.32604/icces.2023.09368

    Abstract Ferroelectric materials have been widely used in various electromechanical devices such as sensors, actuators, transducers and energy storage devices due to their distinguished electromechanical coupling properties. Ferroelectric materials usually bear large mechanical loads and high electric fields in order to give full play to their potential. The interaction between fracture and dielectric breakdown is able to occur since the filler inside a crack will change the dielectric behaviors around it and dielectric breakdown can change the local mechanical properties of dielectric materials because of its weakening of chemical bonds. Therefore, a comprehensive and in-depth understanding of the fracture and dielectric… More >

  • Open Access

    ARTICLE

    Royal Crown Shaped Polarization Insensitive Perfect Metamaterial Absorber for C-, X-, and Ku-Band Applications

    Md. Salah Uddin Afsar1, Mohammad Rashed Iqbal Faruque1,*, Sabirin Abdullah1, Mohammad Tariqul Islam2

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 455-469, 2023, DOI:10.32604/cmc.2023.036655

    Abstract This study proposed a new royal crown-shaped polarisation insensitive double negative triple band microwave range electromagnetic metamaterial absorber (MA). The primary purpose of this study is to utilise the exotic characteristics of this perfect metamaterial absorber (PMA) for microwave wireless communications. The fundamental unit cell of the proposed MA consists of two pentagonal-shaped resonators and two inverse C-shaped metallic components surrounded by a split ring resonator (SRR). The bottom thin copper deposit and upper metallic resonator surface are disjoined by an FR-4 dielectric substrate with 1.6 mm thickness. The CST MW studio, a high-frequency electromagnetic simulator has been deployed for… More >

  • Open Access

    ARTICLE

    A Th2-score in the tumor microenvironment as a predictive biomarker of response to Bacillus Calmette Guérin in patients with non-muscle invasive bladder carcinoma: A retrospective study

    GUSTAVO MARTÍN VILLOLDO1, MARÍA TERESA POMBO2, MARIANA ARIS3, JOAQUÍN CHEMI1, PABLO MANDÓ3, SUPRIYA NAGARAJU4, JUAN CAMEAN1, ADRIÁN BURIONI1, DEBORAH EGEA1, MORA AMAT5, JOSÉ LEÓN MELLADO3, JOSÉ MORDOH3, ALBERTO VILLARONGA1, MARÍA MARCELA BARRIO3,*

    Oncology Research, Vol.31, No.2, pp. 207-220, 2023, DOI:10.32604/or.2023.028163

    Abstract Intravesical Bacillus Calmette Guerin (BCG) is the gold standard therapy for intermediate/high-risk nonmuscle invasive bladder cancer (NMIBC). However, the response rate is ~60%, and 50% of non-responders will progress to muscle-invasive disease. BCG induces massive local infiltration of inflammatory cells (Th1) and ultimately cytotoxic tumor elimination. We searched for predictive biomarker of BCG response by analyzing tumor-infiltrating lymphocyte (TIL) polarization in the tumor microenvironment (TME) in pre-treatment biopsies. Pre-treatment biopsies from patients with NMIBC who received adequate intravesical instillation of BCG (n = 32) were evaluated retrospectively by immunohistochemistry. TME polarization was assessed by quantifying the T-Bet+ (Th1) and GATA-3+… More > Graphic Abstract

    A Th2-score in the tumor microenvironment as a predictive biomarker of response to Bacillus Calmette Guérin in patients with non-muscle invasive bladder carcinoma: A retrospective study

  • Open Access

    ARTICLE

    Graphene-Based Active Tunable Metasurfaces for Dynamic Terahertz Absorption and Polarization Conversion

    Haoran Wei, Tian Ji, Jianqing Huang*

    Journal of Renewable Materials, Vol.11, No.2, pp. 731-743, 2023, DOI:10.32604/jrm.2022.022283

    Abstract Simultaneous broadband absorption and polarization conversion are crucial in many practical applications, especially in terahertz communications. Thus, actively tunable metamaterial systems can exploit the graphene-based nanomaterials derived from renewable resources because of the flexible surface conductivity and selective permeability of the nanomaterials at terahertz frequencies. In this paper, we propose a graphene-based active tunable bifunctional metasurface for dynamic terahertz absorption and polarization conversion. The graphene ring presents a certain opening angle (A) along the diagonal of the xoy plane. When A = 0°, the proposed metasurface behaves as a broadband absorber. Numerical results show the feasibility of achieving this polarization-insensitive… More >

  • Open Access

    ARTICLE

    Modelling of Wideband Concentric Ring Frequency Selective Surface for 5G Devices

    Ankush Kapoor1, Pradeep Kumar2,*, Ranjan Mishra3

    CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 341-361, 2023, DOI:10.32604/cmc.2023.028874

    Abstract Frequency selective surfaces (FSSs) play an important role in wireless systems as these can be used as filters, in isolating the unwanted radiation, in microstrip patch antennas for improving the performance of these antennas and in other 5G applications. The analysis and design of the double concentric ring frequency selective surface (DCRFSS) is presented in this research. In the sub-6 GHz 5G FR1 spectrum, a computational synthesis technique for creating DCRFSS based spatial filters is proposed. The analytical tools presented in this study can be used to gain a better understanding of filtering processes and for constructing the spatial filters.… More >

  • Open Access

    ARTICLE

    Incidence and Related Risk Factors of Junctional Ectopic Tachycardia in Infants after Cardiac Surgery for Congenital Heart Disease

    Jae Hee Seol1,4,#, Se Yong Jung1,#, Jae Young Choi1, Han Ki Park2, Young Hwan Park2, Nam Kyun Kim1,3,*

    Congenital Heart Disease, Vol.17, No.5, pp. 569-578, 2022, DOI:10.32604/chd.2022.018436

    Abstract Objective: Junctional ectopic tachycardia is common after cardiac surgery for congenital heart disease. However, its incidence and related risk factors in infants after cardiac surgery are not well known. The objective of this study was to determine the overall incidence and related risk factors for junctional ectopic tachycardia in neonates and infants. Methods: We enrolled a total of 271 patients aged <1 year who underwent open cardiac surgery at Severance Cardiovascular Hospital from January 2018 to December 2020. Exclusion criteria were immediate postoperative mortality, other arrhythmias detected in the perioperative period, and prematurity. Result: The overall incidence of junctional ectopic… More >

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