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  • Open Access

    ARTICLE

    Quasi-Static and Low-Frequency Dynamic Mechanical Analysis Characterization of Graphene Nanoplatelets/Glass Fabric/Bisphenol-A-Based Epoxy Nanocomposites

    Santhanakrishnan Mamallan1, Venkateshwaran Narayanan1,*, Canungo Bhimarao Ragothaman2

    Journal of Polymer Materials, Vol.41, No.3, pp. 105-116, 2024, DOI:10.32604/jpm.2024.056744 - 30 September 2024

    Abstract Glass fabric/polymer composites are widely used in various industrial applications due to their lightweight, exceptional strength, and fatigue resistance. Graphene nanoplatelets, a recently developed type of carbon material, stand out as unique nanofillers due to their 2D quantum confinement and expansive surface area within a polymer matrix. These features make them more effective than traditional carbon nanofillers at enhancing a range of properties. In this study, 3-weight % of graphene nanoplatelets with epoxy resin were used for investigation by varying sonication durations (0, 20, 40, and 60 min) using an ultrasonic bath sonicator. The laminates More >

  • Open Access

    ARTICLE

    Radiative Blood-Based Hybrid Copper-Graphene Nanoliquid Flows along a Source-Heated Leaning Cylinder

    Siti Nur Ainsyah Ghani1, Noor Fadiya Mohd Noor1,2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 1017-1037, 2024, DOI:10.32604/cmes.2023.031372 - 30 December 2023

    Abstract Variant graphene, graphene oxides (GO), and graphene nanoplatelets (GNP) dispersed in blood-based copper (Cu) nanoliquids over a leaning permeable cylinder are the focus of this study. These forms of graphene are highly beneficial in the biological and medical fields for cancer therapy, anti-infection measures, and drug delivery. The non-Newtonian Sutterby (blood-based) hybrid nanoliquid flows are generalized within the context of the Tiwari-Das model to simulate the effects of radiation and heating sources. The governing partial differential equations are reformulated into a nonlinear set of ordinary differential equations using similar transformational expressions. These equations are then… More >

  • Open Access

    ARTICLE

    Study of Galvanic Charging-Discharging Properties of Graphene Nanoplatelets Incorporated Epoxy-Carbon Fabric Composites

    HADIMANI SHIVAKUMAR1, GURUMURTHY G. D.1, BOMMEGOWDA K. B.2, S. PARAMESHWARA3

    Journal of Polymer Materials, Vol.40, No.1-2, pp. 93-103, 2023, DOI:10.32381/JPM.2023.40.1-2.8

    Abstract Polymer composites are increasing in demand in energy storage applications including in the electronic as well as electrical industries due to the ease of processing of these materials with associated advantages like light weight, corrosion resistance, and high mechanical strength. In this investigation, efforts are made to enhance the charging and discharging properties of epoxy/carbon fabric composite by the addition of graphene nanoplatelets (GNPs) into the epoxy/ carbon matrix. The performance of the composites with graphene platelets of 0.5 to 5 wt. % in epoxy were characterized and 1wt.% percolation threshold was observed poor performance… More >

  • Open Access

    ARTICLE

    Effects of platelets on characteristics of lymphocytes cultured in vitro and optimization of adoptive immunotherapy

    CONGLIANG CHEN#, XIAOHONG LENG#, YU ZHANG, JUNMEI HU, DAPENG WEI, PEIPEI WANG*, XIA WANG*

    BIOCELL, Vol.47, No.12, pp. 2661-2669, 2023, DOI:10.32604/biocell.2023.043084 - 27 December 2023

    Abstract Background: T lymphocytes, the main participants of cellular immunity, can express a variety of surface molecules and form different lymphocyte subsets under the induction of different factors to play the functions of immune regulation and immune killing. Studies have shown that platelets play a crucial role in maintaining the stable differentiation of lymphocytes and the balance in immunomodulation. Therefore, it is necessary to study the effect of platelets on lymphocytes in vitro to better understand the role of platelets in the immune system and broaden the application of adoptive immunotherapy. Methods: Cell counting and microscopic observation were… More >

  • Open Access

    ARTICLE

    Characterization of Nanocomposite Membrane Based Bacterial Cellulose Made of Pineapple Waste Reinforced by Graphite Nanoplatelets

    Heru Suryanto1,2,*, Bili Darnanto Susilo3, Jibril Maulana3, Aminnudin3, Uun Yanuhar4, Surjani Wonorahardjo2,5, Husni Wahyu Wijaya2,5, Abu Saad Ansari6

    Journal of Renewable Materials, Vol.10, No.9, pp. 2455-2465, 2022, DOI:10.32604/jrm.2022.020478 - 30 May 2022

    Abstract Waste is the main problem for the environment. Handling waste for various useful applications has a benefit for the future. This work has been studied for handling pineapple peel waste to make composite film bacterial cellulose nanocomposite membrane (BCNM) with addition graphite nanoplatelet (GNP). The concentration of GNP in the membrane influence the membrane properties. The bacterial cellulose (BC) pellicle was synthesized by using media from pineapple peel waste extract. BC pellicle is cleaned with water and NaOH solution to be free from impactors. BCNM is synthesized through the mechanical disintegration stage. The results of… More > Graphic Abstract

    Characterization of Nanocomposite Membrane Based Bacterial Cellulose Made of Pineapple Waste Reinforced by Graphite Nanoplatelets

  • Open Access

    ARTICLE

    Computational Microfluidic Channel for Separation of Escherichia coli from Blood-Cells

    Chinnapalli Likith Kumar1,*, A. Vimala Juliet1, Bandaru Ramakrishna2, Shubhangi Chakraborty1, Mazin Abed Mohammed3, Kalakanda Alfred Sunny4

    CMC-Computers, Materials & Continua, Vol.67, No.2, pp. 1369-1384, 2021, DOI:10.32604/cmc.2021.015116 - 05 February 2021

    Abstract Microfluidic channels play a vital role in separation of analytes of interest such as bacteria and platelet cells, etc., in various biochemical diagnosis procedures including urinary tract infections (UTI) and bloodstream infections. This paper presents the multi physics computational model specifically designed to study the effects of design parameters of a microfluidics channel for the separation of Escherichia coli (E. coli) from various blood constituents including red blood cells (RBC) and platelets. A standard two inlet and a two outlet microchannel of length 805 m with a channel width of 40 m is simulated. The effect of… More >

  • Open Access

    ARTICLE

    Numerical Evaluation of Residual Water Content after Freezing during the Lyophilization of Platelets

    Shaozhi Zhang, Ruoyi Xie, Mengjie Xu, Guangming Chen*

    FDMP-Fluid Dynamics & Materials Processing, Vol.16, No.6, pp. 1177-1189, 2020, DOI:10.32604/fdmp.2020.010352 - 17 December 2020

    Abstract Pre-freezing is an important stage in freeze-drying processes. For the lyophilization of a cell, freezing not only plays a role for primary dehydration, but it also determines the amount of residual (intracellular or extracellular) water, which in turn can influence the solution properties and the choice of operation parameters. The freezing of human platelets in lyoprotectant solution is theoretically investigated here. A two-parameter model and an Arrhenius expression are used to describe cell membrane permeability and its temperature dependency. It is assumed that the intracellular solution is composed of four components: sodium chloride, trehalose, serum… More >

  • Open Access

    ARTICLE

    Application of Smooth Particle Hydrodynamics Method for Modelling Blood Flow with Thrombus Formation

    M. Al-Saad1, C. A. Suarez2, 4, A. Obeidat2, S. P. A. Bordas1, 2, 3, *, S. Kulasegaram1

    CMES-Computer Modeling in Engineering & Sciences, Vol.122, No.3, pp. 831-862, 2020, DOI:10.32604/cmes.2020.08527 - 01 March 2020

    Abstract Thrombosis plays a crucial role in atherosclerosis or in haemostasis when a blood vessel is injured. This article focuses on using a meshless particle-based Lagrangian numerical technique, the smoothed particles hydrodynamic (SPH) method, to study the flow behaviour of blood and to explore the flow parameters that induce formation of a thrombus in a blood vessel. Due to its simplicity and effectiveness, the SPH method is employed here to simulate the process of thrombogenesis and to study the effect of various blood flow parameters. In the present SPH simulation, blood is modelled by two sets More >

  • Open Access

    ARTICLE

    Transfusion‐related acute hepatic injury following postoperative platelets administration in pediatric patients undergoing the Fontan procedure

    Uri Pollak1,2,3,4,*, Tatyana Ruderman5,*, Sharon Borik‐Chiger5,6, David Mishaly5,7, Alain Serraf5,7, Amir Vardi5,8

    Congenital Heart Disease, Vol.14, No.6, pp. 968-977, 2019, DOI:10.1111/chd.12825

    Abstract Objective: The final common pathway of single ventricle patients is the Fontan procedure. Among the immediate postoperative complications is acute hepatic injury presented by marked elevation of liver enzymes (alanine transaminase [ALT] and aspartate transaminase [AST]). We aimed to determine the contribution of blood products transfusion to acute hepatic injury.
    Design: Single center retrospective cohort study.
    Setting: Pediatric Cardiac Intensive Care Unit at a tertiary medical center.
    Patients: Ninety‐nine pediatric patients undergoing the Fontan procedure between January 2009 and December 2016.
    Interventions: None.
    Measurements and Main Results: Out of the four types of blood products, transfusion of platelets was found to… More >

  • Open Access

    ARTICLE

    Phosphodiesterase type 5 inhibitors improve microvascular dysfunction markers in pulmonary arterial hypertension associated with congenital heart disease

    Mariana M. Clavé1, Nair Y. Maeda2, Ana M. Thomaz1, Sergio P. Bydlowski3, Antonio A. Lopes1

    Congenital Heart Disease, Vol.14, No.2, pp. 246-255, 2019, DOI:10.1111/chd.12688

    Abstract Background: Ideally, vasodilator therapies for pulmonary arterial hypertension (PAH) should have a favorable impact on markers of vascular dysfunction, in addition to their known effects on hemodynamics, cardiac function, and patient’s physical capacity.
    Methods: We analyzed circulating (plasma) markers of endothelial and platelet activation/dys‐ function (enzyme‐linked immunoassays) in the specific setting of advanced PAH associated with congenital heart disease, during the course of sildenafil and tadalafil therapies. Thirty‐one patients were enrolled (age 10‐54 years), most of them with chronic hypoxemia and elevated hematocrit. Drugs were administered orally for 6 months (sildenafil [n = 16], 20 mg t.i.d.;… More >

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