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  • Open Access

    REVIEW

    Microglia-precursor cell interactions in health and in pathology

    Estela M. MUÑOZ

    BIOCELL, Vol.42, No.2, pp. 41-46, 2018, DOI:10.32604/biocell.2018.07011

    Abstract Until recently, microglia were mainly known as the resident phagocytes of the brain, i.e. the ‘immunological warriors’ of the brain. However, extensive knowledge is being accumulated about the functions of microglia beyond immunity. Nowadays, it is well accepted that microglial cells are highly dynamic and responsive, and that they intervene in a dual manner in many developmental processes that shape the central nervous system, including neurogenesis, gliogenesis, spatial patterning, synaptic formation and elimination, and neural circuit establishment and maturation. The differentiation and the pool of precursor cells were also shown to be under microglia More >

  • Open Access

    ARTICLE

    Defense reactions of Dermatobia hominis (Diptera: Cuterebridae) larval hemocytes

    Ana Carolina Faraldo, Edy Lello

    BIOCELL, Vol.27, No.2, pp. 197-203, 2003, DOI:10.32604/biocell.2003.27.197

    Abstract The defense reactions against biological (Histoplasma capsulatum and Escherichia coli) and non-biological materials (China ink and nylon thread) were tested in vivo in third instar larvae of Dermatobia hominis. The cellular defense performed by larval hemocytes was observed under electron microscopy. China ink particles were phagocytosed by granular cells 5 h after injection. E. coli cells were internalized by granular cells as early as 5 min after injection and totally cleared 180 min post-injection, when many hemocytes appeared disintegrated and others in process of recovering. H. capsulatum yeasts provoked, 24 h after being injected, the beginning of nodule formation. Nylon More >

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