Xuehui Jing¹, Junchen Guo¹, Zhiyun Wang^2,*

Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 919-937, 2024, DOI:10.32604/fhmt.2024.049689

Abstract In this paper, the combustion conditions in the boiler furnace of a 660 MW tangential fired pulverized coal boiler are numerically simulated at 15% and 20% rated loads, to study the flexibility of coal-fired power units on ultra-low load operation. The numerical results show that the boiler can operate safely at 15% and 20% ultra-low loads, and the combustion condition in the furnace is better at 20% load, and the tangent circles formed by each characteristic section in the furnace are better, and when the boiler load is decreased to 15%, the tangent circles in… More >

Xue-fei Jin, Hai Li, Shi Zong, Hong-yan Li

Oncology Research, Vol.24, No.6, pp. 477-485, 2016, DOI:10.3727/096504016X14685034103716

Abstract Collagen triple helix repeat containing-1 (CTHRC1), a secreted glycoprotein, is frequently upregulated in human cancers. However, the functional role of CTHRC1 in renal cell carcinoma (RCC) remains unclear. Thus, the aim of this study was to explore the role of CTHRC1 in RCC. Our results demonstrated that CTHRC1 was upregulated in RCC tissues and cell lines. Knockdown of CTHRC1 significantly inhibits the proliferation in RCCs. Furthermore, knockdown of CTHRC1 significantly inhibited the epithelial-to-mesenchymal transition (EMT) process in RCCs, as well as suppressed RCC cell migration and invasion. Mechanistically, knockdown of CTHRC1 inhibited the expression of More >

Feng Jiang^*1, Yan Shi^†1, Hong Lu^†, Guojun Li^*

Oncology Research, Vol.24, No.5, pp. 381-389, 2016, DOI:10.3727/096504016X14685034103392

Abstract Armadillo repeat-containing protein 8 (ARMC8) plays an important role in regulating cell migration, proliferation, tissue maintenance, signal transduction, and tumorigenesis. However, the expression pattern and role of ARMC8 in osteosarcoma are still unclear. In this study, our aims were to examine the effects of ARMC8 on osteosarcoma and to explore its underlying mechanism. Our results demonstrated that ARMC8 was overexpressed in osteosarcoma cell lines. Knockdown of ARMC8 significantly inhibited osteosarcoma cell proliferation in vitro and markedly inhibited xenograft tumor growth in vivo. ARMC8 silencing also suppressed the epithelial– mesenchymal transition (EMT) phenotype, as well as More >

Junfeng Zhang^*1, Kun Xu^†1, Lili Shi^*, Li Zhang^*, Zhaohua Zhao^*, Hao Xu^*, Fei Liang^*, Hongbo Li^*, Yan Zhao^*, Xi Xu^*, Yingfang Tian^‡

Oncology Research, Vol.25, No.8, pp. 1317-1327, 2017, DOI:10.3727/096504017X14874323871217

Abstract Increasing studies have suggested that microRNAs (miRNAs) are involved in the development of gliomas. MicroRNA-216a has been reported to be a tumor-associated miRNA in many types of cancer, either as an oncogene or as a tumor suppressor. However, little is known about the function of miR-216a in gliomas. The present study was designed to explore the potential role of miR-216a in gliomas. We found that miR-216a was significantly decreased in glioma tissues and cell lines. Overexpression of miR-216a significantly suppressed the proliferation, migration, and invasion of glioma cells. Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) More >

Jianpeng Liu^*, Wei Li^†, Shunshun Liu^*, Xu Zheng^*, Lin Shi^*, Weitao Zhang^*, Hongfa Yang^*

Oncology Research, Vol.25, No.2, pp. 225-232, 2017, DOI:10.3727/096504016X14732772150587

Abstract Collagen triple helix repeat containing 1 (CTHRC1), an extracellular matrix-related protein, has been found to be upregulated in many solid tumors and contributes to tumorigenesis. We found that CTHRC1 is overexpressed in glioblastoma tissues and cells. By using the technique of RNA interference, the expression of CTHRC1 in the human glioblastoma U-87MG cell line was downregulated, and the proliferation and migration of U-87MG cells were examined. The results showed that the knockdown of CTHRC1 exerts inhibitory effects on the proliferation and migration ability of U-87MG cells. Knockdown of CTHRC1 expression in U-87MG cells resulted in More >

Xuan Liang^*, Qun-Li Men^†, Yong-wei Li^‡, He-Cheng Li^§, Tie Chong^§, Zhao-lun Li^§

Oncology Research, Vol.25, No.1, pp. 99-105, 2017, DOI:10.3727/096504016X14719078133609

Abstract Armadillo repeat-containing protein 8 (ARMc8) is a key factor in regulating cell migration, proliferation, tissue maintenance, and tumorigenesis. However, its role in bladder cancer remains unknown. Thus, in this study we sought to investigate the effect of ARMc8 on the epithelial-to-mesenchymal transition (EMT) progress in bladder cancer cells induced by transforming growth factor-b1 (TGF-β1). Our results found that ARMc8 was highly expressed in bladder cancer cell lines. ARMc8 silencing inhibited the TGF-β1-induced migration and invasion and suppressed the EMT progress in bladder cancer cells. Furthermore, ARMc8 silencing inhibited the TGF-β1-induced expression of β-catenin, cyclin D1, More >

Md. Abdul Quddus¹, Md. Ataur Rahman¹, Razu Ahmed¹, Mohammad Eyakub Ali², Khokan Kumer Sarker³, Md. Alamgir Siddiky⁴, Mohibur Rahman⁴, Lamya Ahmed Alkeridis⁵, Samy Sayed^6,7, Ahmed Gaber^8,9, Akbar Hossain^10,*

Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 901-922, 2024, DOI:10.32604/phyton.2024.049226

Abstract Garden pea productivity and qualities are hampered in zinc (Zn), boron (B), and molybdenum (Mo) deficient soil. Thus, the combination of micronutrients (i.e., Zn, B, and Mo) and rhizobium is necessary to increase the productivity and quality of garden peas, since this management for garden peas is neglected in Bangladesh. Therefore, the present study was made to assess the effectiveness of rhizobium inoculant singly or in combination with the micronutrients (i.e., Zn, B, and Mo) on growth, yield, nutrient uptake, and quality of garden peas. Treatments were: T = Control, T = Rhizobium inoculation at 50… More >

Yuan Ren¹, Yingxian Sun¹, Zhiguang Yang², Yanli Chen^1,*

Congenital Heart Disease, Vol.19, No.2, pp. 157-176, 2024, DOI:10.32604/chd.2024.047930

Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a chronic, progressive, debilitating, and life-threatening complication of pulmonary embolism (PE). Recent technological advances have permitted various treatment options for the treatment of CTEPH, including surgery, angioplasty, and medical treatment, depending on the location and characteristics of lesions. Pulmonary endarterectomy (PEA) is the treatment of choice for CTEPH, as it offers excellent long-term outcomes and a high probability of recovery. Moreover, various medical and interventional therapies are currently being developed for patients with inoperable CTEPH. This review mainly summarizes the current treatment approaches of CTEPH, offering more options for More >

Muhammad Zaman Ali¹, Omer Riaz¹, Hafiz Muhammad Hasnain², Waqas Sharif², Tenvir Ali², Gyu Sang Choi^3,*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2923-2943, 2024, DOI:10.32604/cmc.2024.049139

Abstract In today’s rapidly evolving landscape of communication technologies, ensuring the secure delivery of sensitive data has become an essential priority. To overcome these difficulties, different steganography and data encryption methods have been proposed by researchers to secure communications. Most of the proposed steganography techniques achieve higher embedding capacities without compromising visual imperceptibility using LSB substitution. In this work, we have an approach that utilizes a combination of Most Significant Bit (MSB) matching and Least Significant Bit (LSB) substitution. The proposed algorithm divides confidential messages into pairs of bits and connects them with the MSBs of… More >

Hui Du, Zhiyuan Hu^*, Depeng Lu, Jingrui Liu

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3239-3259, 2024, DOI:10.32604/cmc.2024.046314

Abstract Traditional clustering algorithms often struggle to produce satisfactory results when dealing with datasets with uneven density. Additionally, they incur substantial computational costs when applied to high-dimensional data due to calculating similarity matrices. To alleviate these issues, we employ the KD-Tree to partition the dataset and compute the K-nearest neighbors (KNN) density for each point, thereby avoiding the computation of similarity matrices. Moreover, we apply the rules of voting elections, treating each data point as a voter and casting a vote for the point with the highest density among its KNN. By utilizing the vote counts More >