Ching-Chi Hsu^1,*, Hsin-Hao Lin¹, Kao-Shang Shih²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.3, pp. 1-2, 2024, DOI:10.32604/icces.2024.011792

Abstract Decompression surgery is one of the useful methods to relieve the pressure on the spinal cord and nerves [1]. In computational simulation, various bone material modelling strategies have been used to model cortical bone and cancellous bone of spinal vertebrae [2,3]. However, the effects of the bone material modelling strategies on the biomechanics of the thoracolumbar spine are unclear. Thus, this study aimed to investigate the biomechanics of the thoracolumbar spine with various bone modelling strategies using a patient-specific finite element modelling technique.
Three-dimensional finite element models of the human thoracolumbar spine were developed from the… More >

Jiaojiao Wu^1,#, Dou Fu^2,#, Lili Zhang^1,*, Xiangying Xie³, Xinmei Wang², Xiangying Shen¹, Shanshan Liu², Xu Xu⁴, Hui Cheng⁵, Xiaojie Ma¹, Doudou Lin¹

International Journal of Mental Health Promotion, Vol.26, No.11, pp. 897-904, 2024, DOI:10.32604/ijmhp.2024.056223 - 28 November 2024

Abstract Background: With the rapid aging of China’s population and the increasing prevalence of comorbidities in the elderly, psychological crises have become more common. This study aims to investigate the present status of psychological vulnerability, aging attitudes, and life meaning in elderly patients with comorbidities. Methods: A total of 685 elderly inpatients and outpatients at Renmin Hospital of Wuhan University between July and December 2022 were selected using the simple random sampling method. Social demographic data were collected, and the Attitudes to aging Questionnaire (AAQ), the Chinese Life Meaning Questionnaire (C-MLQ), and the Psychological Vulnerability Scale… More >

YUSHI YANG^1,#, CHUJIAO HU^2,#, SHAN LEI³, XIN BAO³, ZHIRUI ZENG^3,*, WENPENG CAO^4,*

Oncology Research, Vol.32, No.12, pp. 1921-1934, 2024, DOI:10.32604/or.2024.046191 - 13 November 2024

Abstract Background: The heterogeneity of prognosis and treatment benefits among patients with gliomas is due to tumor microenvironment characteristics. However, biomarkers that reflect microenvironmental characteristics and predict the prognosis of gliomas are limited. Therefore, we aimed to develop a model that can effectively predict prognosis, differentiate microenvironment signatures, and optimize drug selection for patients with glioma. Materials and Methods: The CIBERSORT algorithm, bulk sequencing analysis, and single-cell RNA (scRNA) analysis were employed to identify significant cross-talk genes between M2 macrophages and cancer cells in glioma tissues. A predictive model was constructed based on cross-talk gene expression, and… More >

Priyambada Praharaj^1,*, Chandrakant R. Sonawane^2,*, Arunkumar Bongale²

CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.3, pp. 2021-2064, 2024, DOI:10.32604/cmes.2024.056289 - 31 October 2024

Abstract This paper represents a detailed and systematic review of one of the most ongoing applications of computational fluid dynamics (CFD) in biomedical applications. Beyond its various engineering applications, CFD has started to establish a presence in the biomedical field. Cardiac abnormality, a familiar health issue, is an essential point of investigation by research analysts. Diagnostic modalities provide cardiovascular structural information but give insufficient information about the hemodynamics of blood. The study of hemodynamic parameters can be a potential measure for determining cardiovascular abnormalities. Numerous studies have explored the rheological behavior of blood experimentally and numerically.… More >

Wen Zhang^1,2, Ting Wu^1,2, Xijian Chen^1,3, Hong Luo^1,2,*, Yifei Li^1,4,*

Congenital Heart Disease, Vol.19, No.4, pp. 399-406, 2024, DOI:10.32604/chd.2024.055178 - 31 October 2024

Abstract This article has no abstract. More >

Hamed Taherdoost^1,2,3,4,*

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 79-104, 2024, DOI:10.32604/cmc.2024.054378 - 15 October 2024

Abstract Technical and accessibility issues in hospitals often prevent patients from receiving optimal mental and physical health care, which is essential for independent living, especially as societies age and chronic diseases like diabetes and cardiovascular disease become more common. Recent advances in the Internet of Things (IoT)-enabled wearable devices offer potential solutions for remote health monitoring and everyday activity recognition, gaining significant attention in personalized healthcare. This paper comprehensively reviews wearable healthcare technology integrated with the IoT for continuous vital sign monitoring. Relevant papers were extracted and analyzed using a systematic numerical review method, covering various More >

EGOR V. BATOROV^1,2,*, ALISA D. INESHINA², TATIANA A. ARISTOVA³, VERA V. DENISOVA³, SVETLANA A. SIZIKOVA³, DARIA S. BATOROVA³, GALINA Y. USHAKOVA³, EKATERINA Y. SHEVELA¹, ELENA R. CHERNYKH¹

Oncology Research, Vol.32, No.10, pp. 1575-1587, 2024, DOI:10.32604/or.2024.047893 - 18 September 2024

Abstract Background: Immune checkpoint ligand-receptor interactions appear to be associated with multiple myeloma (MM) progression. Simultaneously, previous studies showed the possibility of PD-1 and TIM-3 expression on T cells upon stimulation with common γ-chain family cytokines in vitro and during homeostatic proliferation. The aim of the present work was to study the impact of homeostatic proliferation on the expansion of certain T cell subsets up-regulating PD-1 and TIM-3 checkpoint molecules. Methods: The expression of CD25, CD122, CD127 common γ-chain cytokine receptors, phosphorylated signal transducer and activator of transcription-5 (pSTAT5) and eomesodermin (EOMES) was comparatively assessed with flow… More >

Youqi Jiang^1,#, Bing Wu^2,#, Jiahui Chen³, Ruyi Jin³, Guangshan Jin³, Minhao Zhang⁴, Qin Zhou^4,*, Aiji Jiang^2,*

Psycho-Oncologie, Vol.18, No.3, pp. 191-200, 2024, DOI:10.32604/po.2024.053942 - 12 September 2024

Abstract Objective: This study evaluated the effect of resilience on depression among patients with breast cancer from individual and familial perspectives by exploring the mediating and moderating effects of family resilience between individual resilience and depression. Methods: A questionnaire survey was conducted among 337 patients with breast cancer who were admitted to the Oncology Department of Jiangsu Province Hospital. The survey included demographic information, the Connor–Davidson Resilience Scale (CD-RISC), the Family Resilience Assessment Scale (FRAS), and the Chinese version of the Patient Health Questionnaire-9 (PHQ-9) for Depression. The relationship among individual resilience, family resilience, and depression… More >

Huimin Zheng, Minghui Wang^*, Miao Ye

Psycho-Oncologie, Vol.18, No.3, pp. 169-179, 2024, DOI:10.32604/po.2024.052703 - 12 September 2024

Abstract Background: Although fear of cancer recurrence (FCR) is the most important factor affecting the life quality of young breast cancer patients, and it may be affected by the patient’s personality, marital relationship and communication, there is a lack of research on the relationship between adult attachment, self-disclosure and FCR in patients. This study investigated the current situation of FCR in young breast cancer patients, its correlation with adult attachment and self-disclosure and its influencing factors, in order to predict the impact of adult attachment and self-disclosure of patients to spouse on FCR. Methods: A survey… More >

Qian Liu^1,#, Hui Zhang^1,#, Juan Gao², Meiping Sha¹, Lijun Shen¹, Xianfeng Cheng^3,*, Hao Chen^4,*

Psycho-Oncologie, Vol.18, No.3, pp. 213-221, 2024, DOI:10.32604/po.2024.052607 - 12 September 2024

Abstract Background: Keratinocyte carcinoma (KC) is a common malignancy characterized by a high recurrence rate and considerable psychological distress. The incidence of KC is increasing in China, raising concerns about its psychological consequences and adverse effects on quality of life. Demographic and clinical factors are thought to influence mental health outcomes in these patients. Nonetheless, data on the prevalence of anxiety in Chinese patients with KC and the factors associated with this anxiety are notably lacking. Therefore, a comprehensive investigation into the anxiety of patients with KC is imperative. Objective: This study aimed to investigate the… More >