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  • Open Access

    VIEWPOINT

    Future of the current anticoronaviral agents: A viewpoint on the validation for the next COVIDs and pandemics

    AMGAD M. RABIE*

    BIOCELL, Vol.47, No.10, pp. 2133-2139, 2023, DOI:10.32604/biocell.2023.030057 - 08 November 2023

    Abstract Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease still represents a major concern to the relevant scientific and medical communities. The primary concern of drug scientists, virologists, and other concerned specialists in this respect is to find ready-to-use suitable and potent anticoronaviral therapies that are broadly effective against the different species/strains of the coronaviruses in general, not only against the current and previous coronaviruses (e.g., the recently-appeared severe acute respiratory syndrome coronavirus 2 “SARS-CoV-2”), i.e., effective antiviral agents for treatment and/or prophylaxis of any coronaviral infections, including More > Graphic Abstract

    Future of the current anticoronaviral agents: A viewpoint on the validation for the next COVIDs and pandemics

  • Open Access

    ARTICLE

    Blockchain and IIoT Enabled Solution for Social Distancing and Isolation Management to Prevent Pandemics

    Muhammad Saad1, Maaz Bin Ahmad1,*, Muhammad Asif2, Muhammad Khalid Khan1, Toqeer Mahmood3, Elsayed Tag Eldin4,*, Hala Abdel Hameed5,6

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 687-709, 2023, DOI:10.32604/cmc.2023.038335 - 08 June 2023

    Abstract Pandemics have always been a nightmare for humanity, especially in developing countries. Forced lockdowns are considered one of the effective ways to deal with spreading such pandemics. Still, developing countries cannot afford such solutions because these may severely damage the country’s economy. Therefore, this study presents the proactive technological mechanisms for business organizations to run their standard business processes during pandemic-like situations smoothly. The novelty of this study is to provide a state-of-the-art solution to prevent pandemics using industrial internet of things (IIoT) and blockchain-enabled technologies. Compared to existing studies, the immutable and tamper-proof contact… More >

  • Open Access

    REVIEW

    The Primacy of Moringa (Moringa oleifera Lam.) in Boosting Nutrition Status and Immunity Defence Amidst the COVID-19 Catastrophe: A Perspective

    Hirdayesh Anuragi1, Rajesh Kumar Singhal2, Yashfa Tanveer3, Humaira Yasmin3, Ambati Srijan4, Alka Bharati1, Lal Chand5, Sukumar Taria1, Kunasekaran Rajarajan1, Asha Ram1, Arun Kumar Handa1, Ayyanadar Arunachalam1, Khalid Rehman Hakeem6,7,8,*, Deniz Özbilici9, Ayman EL Sabagh10,11,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 1831-1858, 2022, DOI:10.32604/phyton.2022.020540 - 13 May 2022

    Abstract A severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led novel coronavirus disease (COVID-19) outbreak spread through China has become the biggest global public health challenge today. The virus upon several mutations has led to the resurgence of more infectious and lethal variants infecting over 298 million people with more than 5.46 million deaths worldwide by the end of December, 2021. Though vaccines are available, various preventive measures particularly a high body immunity is still extremely important which determines the likelihood of disease severity and subsequent recovery in the current and future pandemics. This review acknowledges the… More >

  • Open Access

    VIEWPOINT

    SARS-CoV-2 induced myocarditis: Current knowledge about its molecular and pathophysiological mechanisms

    DOMENICO MARIA CARRETTA1,§, MARINA DI DOMENICO2,§, ROBERTO LOVERO3, ROBERTO ARRIGONI4, ANGELIKA ELZBIETA WEGIERSKA5, MARIAROSARIA BOCCELLINO2,*, ANDREA BALLINI2,6,*, IOANNIS ALEXANDROS CHARITOS7,#, LUIGI SANTACROCE5,#

    BIOCELL, Vol.46, No.8, pp. 1779-1788, 2022, DOI:10.32604/biocell.2022.020009 - 22 April 2022

    Abstract The existence of an inflammatory process in the heart muscle, related to a progressive worsening of myocardial function, different etiopathogenetic mechanisms concur and often overlap, thus making the diagnosis and the therapeutic approach complex. As the COVID-19 pandemic progresses, the effects of the disease on the organ systems and in particular on the cardiovascular system are becoming more and more profound. Cardiac involvement is a well-known event with a high percentage of findings in the heart’s magnetic field, even in asymptomatic areas. There are numerous uncertainties regarding their evolution, in the long and short term,… More >

  • Open Access

    ARTICLE

    Drone-based AI/IoT Framework for Monitoring, Tracking and Fighting Pandemics

    Abdelhamied A. Ateya1,2, Abeer D. Algarni1, Andrey Koucheryavy3, Naglaa. F. Soliman1,2,*

    CMC-Computers, Materials & Continua, Vol.71, No.3, pp. 4677-4699, 2022, DOI:10.32604/cmc.2022.021850 - 14 January 2022

    Abstract Since World Health Organization (WHO) has declared the Coronavirus disease (COVID-19) a global pandemic, the world has changed. All life's fields and daily habits have moved to adapt to this new situation. According to WHO, the probability of such virus pandemics in the future is high, and recommends preparing for worse situations. To this end, this work provides a framework for monitoring, tracking, and fighting COVID-19 and future pandemics. The proposed framework deploys unmanned aerial vehicles (UAVs), e.g.; quadcopter and drone, integrated with artificial intelligence (AI) and Internet of Things (IoT) to monitor and fight… More >

  • Open Access

    ARTICLE

    Sentiment Analytics: Extraction of Challenging Influencing Factors from COVID-19 Pandemics

    Mahmoud Oglah Al Hasan Baniata*, Sohail Asghar

    Intelligent Automation & Soft Computing, Vol.30, No.3, pp. 821-836, 2021, DOI:10.32604/iasc.2021.018612 - 20 August 2021

    Abstract The advancement in electronic devices and communication technologies in social media have introduced major changes in today’s communication and people have accepted such communicational habits at a rapid pace. The changes involve the way people started interacting with each other, and modern mean of discovering new groups of people, and individuals with similar mindsets, mutual interests, and ideas to share with. As far as the communities are concerned, there are so many social drives (such as “Say No to Plastic”) that need to be discussed on a certain platform for their promotion. Although, it’s quit… More >

  • Open Access

    ARTICLE

    Stressors and Coping Strategies of Medical Staff in the COVID-19 Pandemic in Wuhan

    Long Liu1,2, Yanlin Shi1,*, Xiyan Fei3, Zhenzhen Wang1,4, Zhi Wang1,5, Li Li6, Lin Ding6, Qiaoyuan Yan7,*

    International Journal of Mental Health Promotion, Vol.23, No.3, pp. 319-330, 2021, DOI:10.32604/IJMHP.2021.015699 - 23 July 2021

    Abstract Exploring whether medical staff perceive stress on the assigned medical tasks, what are the specific sources of stress, what are the tangible sources of support they expected to be helpful, and individual coping with stress to provide more accurate, personal support for psychological crisis. This study uses a cross-sectional descriptive survey adopting convenience sampling among the medical staff who worked for over seven days in the infected areas of one Grade 2A and three Grade 3A hospitals during the COVID-19 pandemic. The assessment includes attitude when receiving tasks, major stressors, factors relieving stress, and personal… More >

  • Open Access

    ARTICLE

    Automatic Surveillance of Pandemics Using Big Data and Text Mining

    Abdullah Alharbi1,*, Wael Alosaimi1, M. Irfan Uddin2

    CMC-Computers, Materials & Continua, Vol.68, No.1, pp. 303-317, 2021, DOI:10.32604/cmc.2021.016230 - 22 March 2021

    Abstract COVID-19 disease is spreading exponentially due to the rapid transmission of the virus between humans. Different countries have tried different solutions to control the spread of the disease, including lockdowns of countries or cities, quarantines, isolation, sanitization, and masks. Patients with symptoms of COVID-19 are tested using medical testing kits; these tests must be conducted by healthcare professionals. However, the testing process is expensive and time-consuming. There is no surveillance system that can be used as surveillance framework to identify regions of infected individuals and determine the rate of spread so that precautions can be… More >

  • Open Access

    ARTICLE

    Managing Delivery of Safeguarding Substances as a Mitigation Against Outbreaks of Pandemics

    Said Ali Hassan1, Khalid Alnowibet2,3, Prachi Agrawal4, Ali Wagdy Mohamed5,6,*

    CMC-Computers, Materials & Continua, Vol.68, No.1, pp. 1161-1181, 2021, DOI:10.32604/cmc.2021.015494 - 22 March 2021

    Abstract The optimum delivery of safeguarding substances is a major part of supply chain management and a crucial issue in the mitigation against the outbreak of pandemics. A problem arises for a decision maker who wants to optimally choose a subset of candidate consumers to maximize the distributed quantities of the needed safeguarding substances within a specific time period. A nonlinear binary mathematical programming model for the problem is formulated. The decision variables are binary ones that represent whether to choose a specific consumer, and design constraints are formulated to keep track of the chosen route.… More >

  • Open Access

    ARTICLE

    Social Distancing and Isolation Management Using Machine-to-Machine Technologies to Prevent Pandemics

    Muhammad Saad1, Maaz Bin Ahmad1, Muhammad Asif2,*, Khalid Masood2, Mohammad A. Al Ghamdi3

    CMC-Computers, Materials & Continua, Vol.67, No.3, pp. 3545-3562, 2021, DOI:10.32604/cmc.2021.015720 - 01 March 2021

    Abstract Social distancing and self-isolation management are crucial preventive measures that can save millions of lives during challenging pandemics of diseases such as the Spanish flu, swine flu, and coronavirus disease 2019 (COVID-19). This study describes the comprehensive and effective implementation of the Industrial Internet of Things and machine-to-machine technologies for social distancing and smart self-isolation management. These technologies can help prevent outbreaks of any disease that can disperse widely and develop into a pandemic. Initially, a smart wristband is proposed that incorporates Bluetooth beacon technology to facilitate the tracing and tracking of Bluetooth Low Energy… More >

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