Claudia G. REIDES1,2, Romina M. LASAGNI VITAR1,2, Agustina PEVERINI1, Natasha S. JANEZIC1, Ailen G. HVOZDA ARANA1, Sandra M. FERREIRA1,2, Susana F. LLESUY1,2*
BIOCELL, Vol.40, No.1, pp. 51-54, 2016, DOI:10.32604/biocell.2016.40.051
Abstract The purpose of this study was to evaluate the redox status changes of primary visual targets in the rat
brain of a high pressure-induced glaucoma model. The animal model consisted of inducing ocular hypertension by
cauterizing two episcleral veins on the left eye. The markers of oxidative damage and the oxidative balance evaluated
in the brain seven days postoperative were: nitrites concentration, levels of non-enzymatic antioxidants and antioxidant enzymes activity.
The increase in the nitrite content, which could be the result of the enhancement in the production of nitrogen
species, and in the activity of NADPH… More >
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