Mehmet Sitki Copur^*†, Julie Marie Wurdeman^†, Debra Nelson^*, Ryan Ramaekers^*, Dron Gauchan^*, David Crockett^*

Oncology Research, Vol.26, No.3, pp. 515-518, 2018, DOI:10.3727/096504017X15128550060375

Abstract Solid tumors involving glandular organs express mucin glycoprotein that is eventually shed into the circulation. As a result, these proteins can easily be measured in the serum and be used as potential tumor markers. The most commonly used tumor markers for breast cancer are CA27-29 and CA15-3, which both measure the glycoprotein product of the mucin-1 (MUC1) gene. CA27-29 has been approved by the US Food and Drug Administration for monitoring disease activity in breast cancer patients. Most oncology clinical practice guidelines do not recommend the use of tumor markers for routine surveillance of early… More >

Samar M. Alqhtani¹, Toufique A. Soomro^2,*, Faisal Bin Ubaid³, Ahmed Ali⁴, Muhammad Irfan⁵, Abdullah A. Asiri⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1539-1562, 2024, DOI:10.32604/cmes.2024.051475

Abstract Cancer-related to the nervous system and brain tumors is a leading cause of mortality in various countries. Magnetic resonance imaging (MRI) and computed tomography (CT) are utilized to capture brain images. MRI plays a crucial role in the diagnosis of brain tumors and the examination of other brain disorders. Typically, manual assessment of MRI images by radiologists or experts is performed to identify brain tumors and abnormalities in the early stages for timely intervention. However, early diagnosis of brain tumors is intricate, necessitating the use of computerized methods. This research introduces an innovative approach for… More > Graphic Abstract

Luda Chen¹, Kuangzhu Bao², Ying Chen², Jingang Hao^2,*, Jianfeng He^1,3,*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 409-427, 2024, DOI:10.32604/cmc.2024.048507

Abstract Pancreatic diseases, including mass-forming chronic pancreatitis (MFCP) and pancreatic ductal adenocarcinoma (PDAC), present with similar imaging features, leading to diagnostic complexities. Deep Learning (DL) methods have been shown to perform well on diagnostic tasks. Existing DL pancreatic lesion diagnosis studies based on Magnetic Resonance Imaging (MRI) utilize the prior information to guide models to focus on the lesion region. However, over-reliance on prior information may ignore the background information that is helpful for diagnosis. This study verifies the diagnostic significance of the background information using a clinical dataset. Consequently, the Prior Difference Guidance Network (PDGNet)… More >

Manas Ranjan Prusty¹, Rishi Dinesh², Hariket Sukesh Kumar Sheth², Alapati Lakshmi Viswanath², Sandeep Kumar Satapathy^2,3,*

CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3077-3094, 2023, DOI:10.32604/cmc.2023.042718

Abstract This paper presents a novel computerized technique for the segmentation of nuclei in hematoxylin and eosin (H&E) stained histopathology images. The purpose of this study is to overcome the challenges faced in automated nuclei segmentation due to the diversity of nuclei structures that arise from differences in tissue types and staining protocols, as well as the segmentation of variable-sized and overlapping nuclei. To this extent, the approach proposed in this study uses an ensemble of the UNet architecture with various Convolutional Neural Networks (CNN) architectures as encoder backbones, along with stain normalization and test time… More >

Dawei Liang^1,2,4, Meng Wu^1,*, Yan Hu³

CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 279-293, 2023, DOI:10.32604/cmc.2023.035279

Abstract As an indispensable part of identity authentication, offline writer identification plays a notable role in biology, forensics, and historical document analysis. However, identifying handwriting efficiently, stably, and quickly is still challenging due to the method of extracting and processing handwriting features. In this paper, we propose an efficient system to identify writers through handwritten images, which integrates local and global features from similar handwritten images. The local features are modeled by effective aggregate processing, and global features are extracted through transfer learning. Specifically, the proposed system employs a pre-trained Residual Network to mine the relationship… More >

Yong Chen^1,*, Chao Xu¹, Jing Selena He², Sheng Xiao³

Journal of Quantum Computing, Vol.4, No.2, pp. 75-84, 2022, DOI:10.32604/jqc.2022.031312

Abstract With the rapid development of information technology, audit objects and audit itself are more and more inseparable from software. As an important means of software security audit, code security audit will become an important aspect of future audit that cannot be ignored. However, the existing code security audit is mainly based on source code, which is difficult to meet the audit needs of more and more programming languages and binary commercial software. Based on the idea of normalized transformation, this paper constructs a cross language code security audit framework (CLCSA). CLCSA first uses compile/decompile technology… More >

Zhipeng Bin¹, Huihuang Zhao^1,2,*, Xiaoman Liang^1,2, Wenli Chen¹

Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 971-983, 2023, DOI:10.32604/iasc.2023.037270

Abstract The main challenges in face swapping are the preservation and adaptive superimposition of attributes of two images. In this study, the Face Swapping Attention Network (FSA-Net) is proposed to generate photorealistic face swapping. The existing face-swapping methods ignore the blending attributes or mismatch the facial keypoint (cheek, mouth, eye, nose, etc.), which causes artifacts and makes the generated face silhouette non-realistic. To address this problem, a novel reinforced multi-aware attention module, referred to as RMAA, is proposed for handling facial fusion and expression occlusion flaws. The framework includes two stages. In the first stage, a More >

Cong Lin¹, Chenghao Qiu¹, Can Wu¹, Siling Feng^1,*, Mengxing Huang^1,2,*

CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 4317-4340, 2023, DOI:10.32604/cmc.2023.036249

Abstract The random-value impulse noise (RVIN) detection approach in image denoising, which is dependent on manually defined detection thresholds or local window information, does not have strong generalization performance and cannot successfully cope with damaged pictures with high noise levels. The fusion of the K-means clustering approach in the noise detection stage is reviewed in this research, and the internal relationship between the flat region and the detail area of the damaged picture is thoroughly explored to suggest an unique two-stage method for gray image denoising. Based on the concept of pixel clustering and grouping, all… More >

Shoukai Lin^1,2,#, Shichang Xu^1,#, Liyan Huang¹, Fuxiang Qiu¹, Yihong Zheng¹, Qionghao Liu¹, Shiwei Ma^1,2, Bisha Wu^1,2, Jincheng Wu^1,2,*

Phyton-International Journal of Experimental Botany, Vol.92, No.4, pp. 1185-1201, 2023, DOI:10.32604/phyton.2023.026752

Abstract Loquat (Eriobotrya japonica Lindl.) is a subtropical evergreen fruit tree that produces fruits with abundant nutrients and medicinal components. Confirming suitable reference genes for a set of loquat samples before qRT-PCR experiments is essential for the accurate quantification of gene expression. In this study, eight candidate reference genes were selected from our previously published RNA-seq data, and primers for each candidate reference gene were designed and evaluated. The Cq values of the candidate reference genes were calculated by RT-qPCR in 31 different loquat samples, including 12 subgroups of developing or abiotic-stressed tissues. Different combinations of stable… More >

Sihua Wang^1,2, Wenhui Zhang^1,2,*, Gaofei Zheng^1,2, Xujie Li^1,2, Yougeng Zhao^1,2

Energy Engineering, Vol.119, No.6, pp. 2431-2445, 2022, DOI:10.32604/ee.2022.020779

Abstract In order to improve the condition monitoring and fault diagnosis of wind turbines, a stacked noise reduction autoencoding network based on group normalization is proposed in this paper. The network is based on SCADA data of wind turbine operation, firstly, the group normalization (GN) algorithm is added to solve the problems of stack noise reduction autoencoding network training and slow convergence speed, and the RMSProp algorithm is used to update the weight and the bias of the autoenccoder, which further optimizes the problem that the loss function swings too much during the update process. Finally, More >