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    PROCEEDINGS

    Numerical Simulation of In Situ Deformation Behavior of Pt-DNA Hydrogel

    Isamu Riku1,*, Arisa Fukatsu1, Koji Mimura1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.3, pp. 1-1, 2024, DOI:10.32604/icces.2024.011356

    Abstract Pt-DNA hydrogel is formed by cross-linking the DNA strands with Pt-ions and the resultant three-dimensionally cross-linked DNA strands’ network is expected be used as a biocompatible polymeric carrier, i.e. the drug delivery platform for in situ tissue repair due to its high toughness. On the other hand, as another essential qualification for the drug delivery platform, the stability of the microstructure of the platform is indispensable.
    To evaluate the stability of the microstructure of Pt-DNA hydrogel, in this study, we at first employ the nonaffine molecular chains’ network model to reproduce the experimental results of the More >

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