Ziying Zhang1,*, Chu Li1, Junwei Zhu1, Qinghong Wu1
The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.010912
Abstract The process of perfusion seeding of cells into a porous scaffold represents a pivotal initial stage in the development of tissue-engineered bones. The rheological behavior of the cell suspension plays a crucial role in influencing the transport and distribution of cells within the scaffold. Currently, there is limited understanding of the non-Newtonian rheology of cell suspensions in complex pores which differs significantly from simple channels or linear shear flow. In this study, we utilize our previously developed mesoscopic model of perfusion cell seeding to investigate the rheological behavior of cell suspensions at the cellular scale. More >
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