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    ARTICLE

    Surgical Repair of Ventricular Septal Defect in Neonates: Indications and Outcomes

    Jae Hong Lee1, Sungkyu Cho2,*, Jae Gun Kwak2, Hye Won Kwon2, Woong-Han Kim2, Mi Kyoung Song3, Sang-Yun Lee3, Gi Beom Kim3, Eun Jung Bae3

    Congenital Heart Disease, Vol.19, No.1, pp. 69-83, 2024, DOI:10.32604/chd.2024.045137 - 20 March 2024

    Abstract Background: The optimal surgical timing and clinical outcomes of ventricular septal defect (VSD) closure in neonates remain unclear. We aimed to evaluate the clinical outcomes of VSD closure in neonates (age ≤ 30 days). Methods: We retrospectively reviewed 50 consecutive neonates who underwent VSD closure for isolated VSDs between August 2003 and June 2021. Indications for the procedure included congestive heart failure/failure to thrive and pulmonary hypertension. Major adverse events (MAEs) were defined as the composite of all-cause mortality, reoperation, persistent atrioventricular block, and significant (≥grade 2) valvular dysfunction. Results: The median age and body weight… More >

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