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  • Open Access

    ARTICLE

    The Neurosurgical Challenge of Primary Central Nervous System Lymphoma Diagnosis: A Multimodal Intraoperative Imaging Approach to Overcome Frameless Neuronavigated Biopsy Sampling Errors

    Roberto Altieri1,2,*, Francesco Certo1, Marco Garozzo1, Giacomo Cammarata1, Massimiliano Maione1, Giuseppa Fiumanò3, Giuseppe Broggi4, Giada Maria Vecchio4, Rosario Caltabiano4, Gaetano Magro4, Giuseppe Barbagallo1

    Oncologie, Vol.24, No.4, pp. 693-706, 2022, DOI:10.32604/oncologie.2022.025393

    Abstract Background: Intracranial lymphoma remains a challenging differential diagnosis in daily neurosurgical practice. We analyzed our early experience with a surgical series of frameless neuronavigated biopsies in Primary CNS Lymphomas (PCNSLs), highlighting the importance of using an intraoperative combined imaging protocol (5-ALA fluorescence, i-CT and 11C-MET-PET) to overcome potential targeting errors secondary to tumor volume reduction after corticosteroid therapy. Materials and Methods: All patients treated for PCNLSs at our center in a 24-month period (1/1/2019 to 31/12/2020) were analyzed. Our cohort included 6 patients (4 males), with a median age of 67 years (59–82). A total of 45 samples were evaluated… More >

  • Open Access

    ARTICLE

    Development of Mobile App to Support the Mobility of Visually Impaired People

    R. Meenakshi1, R. Ponnusamy1,*, Saleh Alghamdi2, Osama Ibrahim Khalaf3, Youseef Alotaibi4

    CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 3473-3495, 2022, DOI:10.32604/cmc.2022.028540

    Abstract In 2017, it was estimated that the number of persons of all ages visually affected would be two hundred and eighty-five million, of which thirty-nine million are blind. There are several innovative technical solutions available to facilitate the movement of these people. The next big challenge for technical people is to give cost-effective solutions. One of the challenges for people with visual impairments is navigating safely, recognizing obstacles, and moving freely between locations in unfamiliar environments. A new mobile application solution is developed, and the application can be installed in android mobile. The application will visualize the environment with portable… More >

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