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  • Open Access

    ARTICLE

    Optimizing Silver Nanoparticle Concentrations to Improve the In Vitro Regeneration and Growth of Phalaenopsis Orchids

    Hay Mon Aung1, Aung Htay Naing2,*, Chang Kil Kim2, Kyeung II Park1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2719-2727, 2025, DOI:10.32604/phyton.2025.068713 - 30 September 2025

    Abstract Phalaenopsis orchids are economically important ornamental crops; however, their commercial micropropagation is often limited by poor rooting efficiency and inconsistent growth. In this study, we investigated the effects of silver nanoparticles (Ag-NPs) on the in vitro regeneration and growth of Phalaenopsis cultivar 611B to determine the optimal concentration of Ag-NPs for improved micropropagation outcomes. Shoot tip explants (2–3 mm)—derived from protocorm-like bodies were cultured on a regeneration medium containing Hyponex (20:20:20 and 6.5:6.5:19), 18 g/L sugar, 2 g/L peptone, 0.8 g/L activated charcoal, 12.5 g/L potato extract, 50 mL/L apple juice, and 10 mg/L 6-benzylaminopurine (6-BA), with… More >

  • Open Access

    ARTICLE

    Inhibition of Breast Cancer Cell Proliferation by 9-Hydroxycamptothecin-Loaded Zeolitic Imidazolate Nanoparticles

    Chuansheng Yang1, Xiaoling Zhou2,3, Ling Luo3, Zirun Luo4, Kaiming Fan5,*, Chenglai Xia2,3,*

    Oncology Research, Vol.33, No.10, pp. 3065-3076, 2025, DOI:10.32604/or.2025.066058 - 26 September 2025

    Abstract Objectives: Novel drug delivery systems have been designed to enhance local drug concentrations while reducing side effects conducive to improved breast cancer treatment outcomes. This study aimed to identify the anti-cancer function of zeolite imidazole ester-based material loaded with camptothecin nanoparticles. Methods: We utilized a zeolitic imidazolate backbone material to fabricate 9-hydroxycamptothecin nanoparticles and investigated their impact on breast cancer cell proliferation. Scanning electron microscopy and Fourier-transform infrared spectroscopy revealed changes in the carrier skeleton of the loaded 9-hydroxyl camptothecin, characterized by a reduction in surface smoothness, accompanied by slight collapses and folds on the… More >

  • Open Access

    ARTICLE

    Hybrid Nanofluids Mixed Convection inside a Partially Heated Square Enclosure with Driven Sidewalls

    Meriem Bounib1, Aicha Bouhezza2,3,*, Abdelkrim Khelifa4, Mohamed Teggar5, Hasan Köten6, Aissa Atia7, Yassine Cherif 8

    Frontiers in Heat and Mass Transfer, Vol.23, No.4, pp. 1323-1350, 2025, DOI:10.32604/fhmt.2025.065254 - 29 August 2025

    Abstract This study investigates laminar convection in three regimes (forced convection, mixed convection, and natural convection) of a bi-nanofluid (Cu-Al2O3-water)/mono-nanofluid (Al2O3-water) inside a square enclosure of sliding vertical walls which are kept at cold temperature and moving up, down, or in opposite directions. The enclosure bottom is heated partially by a central heat source of various sizes while the horizontal walls are considered adiabatic. The thermal conductivity and dynamic viscosity are dependent on temperature and nanoparticle size. The conservation equations are implemented in the solver ANSYS R2 (2020). The numerical predictions are successfully validated by comparison with… More >

  • Open Access

    ARTICLE

    Targeting c-Src/PKCα/MAPK/NF-κB: Salvianolic Acid A as a Protective Agent against Silica Nanoparticle-Induced Lung Inflammation

    Yan-Jyun Lin1,#, I-Ta Lee2,#, Wen-Bin Wu3,4, Chien-Chung Yang5,6, Chiang-Wen Lee7,8,9, Fuu-Jen Tsai10,11,12, Hui-Ching Tseng13, Wei-Ning Lin4, Li-Der Hsiao4, Chuen-Mao Yang4,*

    BIOCELL, Vol.49, No.7, pp. 1265-1290, 2025, DOI:10.32604/biocell.2025.066223 - 25 July 2025

    Abstract Background: Silica nanoparticles (SiNPs), commonly utilized in industrial and biomedical fields, are known to provoke pulmonary inflammation by elevating cyclooxygenase-2 (COX-2) levels in human pulmonary alveolar epithelial cells (HPAEpiCs). Salvianolic acid A (SAA), a water-soluble polyphenol extracted from Salvia miltiorrhiza (Danshen), possesses well-documented antioxidant and anti-inflammatory activities. Nevertheless, its potential to counteract SiNP-induced inflammatory responses in the lung has not been thoroughly explored. Objective: This study aimed to evaluate the protective role and mechanistic actions of SAA against SiNP-triggered inflammation in both cellular and animal models. Methods: HPAEpiCs were pre-incubated with SAA prior to SiNP exposure to… More >

  • Open Access

    ARTICLE

    Long-Term Synergistic Antimicrobial Tannic Acid-Silver Nanoparticles Coating

    Irina Postnova1,2, Valeria Kurilenko3, Yury Shchipunov1,*

    Journal of Renewable Materials, Vol.13, No.7, pp. 1293-1313, 2025, DOI:10.32604/jrm.2025.02024-0032 - 22 July 2025

    Abstract The main objective of the study was to prepare a highly active antimicrobial remedy by combining active agents such as tannic acid and silver nanoparticles, which are usually used separately. This was achieved by applying a coating of 11 alternating layers of an insoluble complex of tannic acid with polyvinyl alcohol on paper by the layer-by-layer approach, on the surface of which uniformly distributed spherical silver nanoparticles of uniform size, mainly 20–30 nm, were synthesized by in situ reduction using tannic acid, which also acts as a stabilizer, or an external reducing agent, which prevented polyphenol More > Graphic Abstract

    Long-Term Synergistic Antimicrobial Tannic Acid-Silver Nanoparticles Coating

  • Open Access

    REVIEW

    Recent Advancements in Nanocomposites-Based Antibiofilm Food Packaging

    Bandana Padhan1,#, Rajkumar Patel2,#, Priyanka Bhowmik3, Ananya Roy1, Joyjyoti Das1,*, Yong Yu4,5, Madhumita Patel6,*

    Journal of Polymer Materials, Vol.42, No.2, pp. 411-433, 2025, DOI:10.32604/jpm.2024.059156 - 14 July 2025

    Abstract The food industry prioritizes food safety throughout the entire production process. This involves closely monitoring and evaluating all potential sources of biological or chemical contamination, starting from entering raw materials into the production chain and continuing to the final product. Biofilms on food surfaces or containers can harbor dangerous pathogens, such as Listeria monocytogenes. Therefore, it is essential to continuously manage microbial contamination on food contact surfaces to prevent foodborne infections. Recently, there has been increasing interest in using nanomaterials as surface coatings with antimicrobial properties in the food industry, especially since traditional disinfectants or antibiotics… More >

  • Open Access

    ARTICLE

    Thermal Performance Analysis of Shell and Tube Heat Exchanger Using Hybrid Nanofluids Based on Al2O3, TiO2, and ZnO Nanoparticles

    Ans Ahmed Memon1, Laveet Kumar1,2,*, Abdul Ghafoor Memon1, Khanji Harijan1, Ahmad K. Sleiti2

    Frontiers in Heat and Mass Transfer, Vol.23, No.3, pp. 833-856, 2025, DOI:10.32604/fhmt.2025.064805 - 30 June 2025

    Abstract Climate change, rising fuel prices, and fuel security are some challenges that have emerged and have grown worldwide. Therefore, to overcome these obstacles, highly efficient thermodynamic devices and heat recovery systems must be introduced. According to reports, much industrial waste heat is lost as flue gas from boilers, heating plants, etc. The primary objective of this study is to investigate and compare unary (Al2O3) thermodynamically, binary with three different combinations of nanoparticles namely (Al2O3 + TiO2, TiO2 + ZnO, Al2O3 + ZnO) and ternary (Al2O3 + TiO2 + ZnO) as a heat transfer fluid. Initially, three different types of… More > Graphic Abstract

    Thermal Performance Analysis of Shell and Tube Heat Exchanger Using Hybrid Nanofluids Based on Al<sub>2</sub>O<sub>3</sub>, TiO<sub>2</sub>, and ZnO Nanoparticles

  • Open Access

    REVIEW

    Performance Enhancement of Chitosan for Food Packaging: Impact of Additives and Nanotechnology

    Panji Setya Utama Putra1, Damar Rastri Adhika2,3,*, Lia Amelia Tresna Wulan Asri4, Suprijadi Suprijadi3,5

    Journal of Renewable Materials, Vol.13, No.6, pp. 1043-1070, 2025, DOI:10.32604/jrm.2025.02024-0002 - 23 June 2025

    Abstract The continuous increase in petroleum-based plastic food packaging has led to numerous environmental concerns. One effort to reduce the use of plastic packaging in food is through preservation using biopolymer-based packaging. Among the many types of biopolymers, chitosan is widely used and researched due to its non-toxic, antimicrobial, and antifungal properties. Chitosan is widely available since it is a compound extracted from seafood waste, especially shrimps and crabs. The biodegradability and biocompatibility of chitosan also showed good potential for various applications. These characteristics and properties make chitosan an attractive biopolymer to be implemented as food… More > Graphic Abstract

    Performance Enhancement of Chitosan for Food Packaging: Impact of Additives and Nanotechnology

  • Open Access

    REVIEW

    Zinc Oxide Nanoparticles: Abiotic Stress Tolerance in Fruit Crops Focusing on Sustainable Production

    Meryam Manzoor1, Konstantin Korolev2, Maryam3, Riaz Ahmad4,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.5, pp. 1401-1418, 2025, DOI:10.32604/phyton.2025.063930 - 29 May 2025

    Abstract The productivity of fruit crops is badly affected by abrupt changes in climatic conditions. It is a matter of concern for fruit tree researchers to feed the huge population within the available resources. The adverse effects of abiotic stresses are increasing due to fluctuations in climate change. Several abiotic stresses (salinity, drought, water logging, minerals deficiency, temperature extremities and heavy metals) are reducing the overall productivity of crops. Therefore, the application of different management approaches, i.e., phytohormones, nanoparticles, organic amendments, microbes and molecular aspects are effective for the mitigation of abiotic stresses in fruit crops.… More >

  • Open Access

    REVIEW

    Ferroptosis Mediates Zinc Toxicity: Implications for Cancer Therapy

    Anton Tkachenko*

    BIOCELL, Vol.49, No.5, pp. 721-741, 2025, DOI:10.32604/biocell.2025.063301 - 27 May 2025

    Abstract Ferroptosis is an iron-driven, phospholipid hydroperoxide-mediated cell death, which has recently emerged as an attractive tool in cancer research due to its ability to govern the anti-tumor immune response. A growing research interest in ferroptosis biology has revealed the contribution of this regulated cell death to multiple diseases. In addition to iron, ferroptosis has been reported to be triggered by multiple heavy metals, which sheds light on the novel aspects of heavy metals-induced cytotoxicity. In this review, the ability of zinc, an essential biogenic element with a wide array of biological functions, to modulate ferroptosis… More >

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