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  • Open Access

    PROCEEDINGS

    Research on the Synergistic Mechanism of Photothermal-Chemotherapy-Immunotherapy of Multi-Functional Nanoparticles Against Gastric Cancer

    Erdong Shen1, Ting Pan1, Pan Guo1, Ke Chen1, Rui Xu1, Mei Yang1, Dahe Zhan1, Fang Fang1, Qinghui Wu1,*, Jianbing Hu1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-3, 2024, DOI:10.32604/icces.2024.012772

    Abstract Objective
    This study investigates the synergistic effects of a novel multifunctional nanoparticle on gastric cancer treatment through photothermal therapy, chemotherapy, and immunotherapy.

    Method
    Synthesize hollow mesoporous Prussian blue nanoparticles and load them with luteolin. Use exosomes to encapsulate the nanoparticles and modify the surface of the targeted peptide GX1. Detect the morphology of nanoparticles using a nanoparticle size analyzer and transmission electron microscopy. Use Coomassie Brilliant Blue to detect the effect of extracellular vesicle encapsulation. Detect the thermal conversion efficiency of nanoparticles under specific laser irradiation through infrared and ultraviolet spectroscopy, as well as the release rate… More >

  • Open Access

    REVIEW

    Impact of nanoparticles on immune cells and their potential applications in cancer immunotherapy

    JYOTHI B. NAIR1,2, ANU MARY JOSEPH3, SANOOP P.4, MANU M. JOSEPH5,*

    BIOCELL, Vol.48, No.11, pp. 1579-1602, 2024, DOI:10.32604/biocell.2024.054879 - 07 November 2024

    Abstract Nanoparticles represent a heterogeneous collection of materials, whether natural or synthetic, with dimensions aligning in the nanoscale. Because of their intense manifestation with the immune system, they can be harvested for numerous bio-medical and biotechnological advancements mainly in cancer treatment. This review article aims to scrutinize various types of nanoparticles that interact differently with immune cells like macrophages, dendritic cells, T lymphocytes, and natural killer (NK) cells. It also underscores the importance of knowing how nanoparticles influence immune cell functions, such as the production of cytokines and the presentation of antigens which are crucial for… More >

  • Open Access

    ARTICLE

    A Mathematical Modeling of 3D Cubical Geometry Hypothetical Reservoir under the Effect of Nanoparticles Flow Rate, Porosity, and Relative Permeability

    Mudasar Zafar1,2,3,*, Hamzah Sakidin1, Abida Hussain1, Loshini Thiruchelvam4, Mikhail Sheremet5, Iskandar Dzulkarnain3, Roslinda Nazar6, Abdullah Al-Yaari1, Rizwan Safdar7,8

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.2, pp. 1193-1211, 2024, DOI:10.32604/cmes.2024.049259 - 27 September 2024

    Abstract This study aims to formulate a steady-state mathematical model for a three-dimensional permeable enclosure (cavity) to determine the oil extraction rate using three distinct nanoparticles, SiO2, Al2O3, and Fe2O3, in unconventional oil reservoirs. The simulation is conducted for different parameters of volume fractions, porosities, and mass flow rates to determine the optimal oil recovery. The impact of nanoparticles on relative permeability ( and water is also investigated. The simulation process utilizes the finite volume ANSYS Fluent. The study results showed that when the mass flow rate at the inlet is low, oil recovery goes up. In addition, More >

  • Open Access

    ARTICLE

    Enhanced Dye Adsorption and Bacterial Removal of Magnetic Nanoparticle-Functionalized Bacterial Cellulose Acetate Membranes

    Heru Suryanto1,2,*, Daimon Syukri3, Fredy Kurniawan4, Uun Yanuhar5, Joseph Selvi Binoj6, Sahrul Efendi2, Fajar Nusantara2, Jibril Maulana7, Nico Rahman Caesar5, Komarudin Komarudin2

    Journal of Renewable Materials, Vol.12, No.9, pp. 1605-1624, 2024, DOI:10.32604/jrm.2024.054047 - 25 September 2024

    Abstract Utilizing biomass waste as a potential resource for cellulose production holds promise in mitigating environmental consequences. The current study aims to utilize pineapple biowaste extract in producing bacterial cellulose acetate-based membranes with magnetic nanoparticles (Fe3O4 nanoparticles) through the fermentation and esterification process and explore its characteristics. The bacterial cellulose fibrillation used a high-pressure homogenization procedure, and membranes were developed incorporating 0.25, 0.50, 0.75, and 1.0 wt.% of Fe3O4 nanoparticles as magnetic nanoparticle for functionalization. The membrane characteristics were measured in terms of Scanning Electron Microscope, X-ray diffraction, Fourier Transform Infrared, Vibrating Sample Magnetometer, antibacterial activity, bacterial… More > Graphic Abstract

    Enhanced Dye Adsorption and Bacterial Removal of Magnetic Nanoparticle-Functionalized Bacterial Cellulose Acetate Membranes

  • Open Access

    ARTICLE

    FPGA Accelerators for Computing Interatomic Potential-Based Molecular Dynamics Simulation for Gold Nanoparticles: Exploring Different Communication Protocols

    Ankitkumar Patel1, Srivathsan Vasudevan1,*, Satya Bulusu2,*

    CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 3803-3818, 2024, DOI:10.32604/cmc.2024.052851 - 12 September 2024

    Abstract Molecular Dynamics (MD) simulation for computing Interatomic Potential (IAP) is a very important High-Performance Computing (HPC) application. MD simulation on particles of experimental relevance takes huge computation time, despite using an expensive high-end server. Heterogeneous computing, a combination of the Field Programmable Gate Array (FPGA) and a computer, is proposed as a solution to compute MD simulation efficiently. In such heterogeneous computation, communication between FPGA and Computer is necessary. One such MD simulation, explained in the paper, is the (Artificial Neural Network) ANN-based IAP computation of gold (Au147 & Au309) nanoparticles. MD simulation calculates the forces… More >

  • Open Access

    SHORT COMMUNICATION

    Preparation of Regenerated Silk Fibroin Hybrid Fibers with Hydrogen Peroxide Sensing Properties by Wet Spinning

    Song Lu1, Jianjun Guo2, Richard Ansah Herman1, Xinyi Wu1, Lin Ma1, Guohua Wu1,*

    Journal of Renewable Materials, Vol.12, No.6, pp. 1043-1055, 2024, DOI:10.32604/jrm.2024.051767 - 02 August 2024

    Abstract Silk is widely used in the production of high-quality textiles. At the same time, the amount of silk textiles no longer in use and discarded is increasing, resulting in significant waste and pollution. This issue is of great concern in many countries where silk is used. Hydrogen peroxide as a naturally occurring compound is an important indicator of detection in both biology and the environment. This study aims to develop a composite fiber with hydrogen peroxide-sensing properties using discarded silk materials. To achieve this goal, firstly, polydopamine (PDA) was used to encapsulate the ZnFeO NPs… More > Graphic Abstract

    Preparation of Regenerated Silk Fibroin Hybrid Fibers with Hydrogen Peroxide Sensing Properties by Wet Spinning

  • Open Access

    ARTICLE

    One-Step to Prepare Lignin Based Fluorescent Nanoparticles with Excellent Radical Scavenging Activity

    Xujing Zhang1, Hatem Abushammala2, Debora Puglia3, Binbao Lu1, Pengwu Xu1, Weijun Yang1,*, Piming Ma1

    Journal of Renewable Materials, Vol.12, No.5, pp. 895-908, 2024, DOI:10.32604/jrm.2024.049810 - 17 July 2024

    Abstract Fluorescent nanomaterials have attracted much attention, due to their unique luminescent properties and promising applications in biomedical areas. In this study, lignin based fluorescent nanoparticles (LFNP) with high yield (up to 32.4%) were prepared from lignin nanoparticles (LNP) by one-pot hydrothermal method with ethylenediamine (EDA) and citric acid. Morphology and chemical structure of LFNP were investigated by SEM, FT-IR, and zeta potential, and it was found that the structure of LFNP changed with the increase of citric acid addition. LFNP showed the highest fluorescence intensity under UV excitation at wavelengths of 375–385 nm, with emission More > Graphic Abstract

    One-Step to Prepare Lignin Based Fluorescent Nanoparticles with Excellent Radical Scavenging Activity

  • Open Access

    ARTICLE

    Film Flow of Nano-Micropolar Fluid with Dissipation Effect

    Abuzar Abid Siddiqui1, Mustafa Turkyilmazoglu2,3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2487-2512, 2024, DOI:10.32604/cmes.2024.050525 - 08 July 2024

    Abstract The physical problem of the thin film flow of a micropolar fluid over a dynamic and inclined substrate under the influence of gravitational and thermal forces in the presence of nanoparticles is formulated. Five different types of nanoparticle samples are accounted for in this current study, namely gold Au, silver Ag, molybdenum disulfide MoS2, aluminum oxide Al2O3, and silicon dioxide SiO2. Blood, a micropolar fluid, serves as the common base fluid. An exact closed-form solution for this problem is derived for the first time in the literature. The results are particularly validated against those for the Newtonian fluid… More >

  • Open Access

    REVIEW

    Coffee Leaf Rust (Hemileia vastatrix) Disease in Coffee Plants and Perspectives by the Disease Control

    Alexis Salazar-Navarro1, Victor Ruiz-Valdiviezo2, Jose Joya-Dávila3, Daniel Gonzalez-Mendoza1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 923-949, 2024, DOI:10.32604/phyton.2024.049612 - 28 May 2024

    Abstract Coffee Leaf Rust (CLR) is caused by Hemileia vastatrix in Coffea spp. It is one of the most dangerous phytopathogens for coffee plantations in terms of coffee productivity and coffee cup quality. In this review, we resume the problem of CLR in Mexico and the pathogenesis of H. vastatrix. The review abord plant-pathogen interactions which lead a compatible or incompatible interactions and result in CLR disease or resistance, respectively. The review abord Coffea spp. defense response pathways involved in H. vastatrix pathogenicity. Additionally, current measures to control H. vastatrix proliferation and germination were aborded focused on phytosanitary actions, and biological More >

  • Open Access

    ARTICLE

    Photosynthetic Gas Exchange and Nitrogen Assimilation in Green Bean Plants Supplied with Two Sources of Silicon

    Julio C. Anchondo-Páez, Esteban Sánchez*, Carlos A. Ramírez-Estrada, Alondra Salcido-Martínez, Erick H. Ochoa-Chaparro

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 963-980, 2024, DOI:10.32604/phyton.2024.048742 - 28 May 2024

    Abstract Beans contain a wide range of vitamins, proteins, calcium, and zinc which make them an important food source for many countries. To meet the demand for bean production worldwide, large amounts of fertilizers and pesticides are used. However, the cost of production and environmental impact increases. To produce food sustainably, the use of beneficial nutrients such as silicon as a biostimulant has been proposed. However, information about the effect of different sources of silicon on the metabolism of bean plants is scarce. Bean plants cv. Strike were grown in pots for 60 days and the… More >

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